Ben Roethlisberger had the best passer rating by a quarterback in a game in 2016, with a 152.5 rating against the Chiefs on October 2, 2016.

which quarterback has the highest passer rating in a game in 2016
Interpreted as:
Which quarterback has the highest passer rating in a regular-season game in 2016?
10/2/2016Roethlisberger12/11/2016Rodgers11/13/2016Mariota12/26/2016Prescott10/27/2016Mariota12/5/2016Luck11/24/2016Roethlisberger11/20/2016Cousins11/3/2016Ryan12/18/2016Ryan10/2/2016Ryan11/6/2016Prescott10/2/2016Siemian10/16/2016Brady1/1/2017Ryan10/16/2016Stafford11/27/2016Brees9/18/2016Rivers11/7/2016Wilson10/30/2016Brady12/24/2016Rodgers9/18/2016Garoppolo10/30/2016Foles152.5150.8149.8148.3148.1147.6146.0145.8144.7144.5142.0141.8141.7140.0139.9139.8139.6138.9137.0137.0136.6135.4135.2
NAMEDATETMOPPRATECMPATTPCTYDSAVGTDTD%INTINT%SCKSCKY
Ben RoethlisbergerBen Roethlisberger10/2/2016PITPITvs. KC
vs.
152.5222781.530011.1518.500.0213
Aaron RodgersAaron Rodgers12/11/2016GBGBvs. SEA
vs.
150.8182378.324610.7313.000.019
Marcus MariotaMarcus Mariota11/13/2016TENTENvs. GB
vs.
149.8192673.129511.3415.400.0113
Dak PrescottDak Prescott12/26/2016DALDALvs. DET
vs.
148.3152075.021210.6315.000.0111
Marcus MariotaMarcus Mariota10/27/2016TENTENvs. JAX
vs.
148.1182281.827012.329.100.000
Andrew LuckAndrew Luck12/5/2016INDIND@ NYJ
@
147.6222878.62789.9414.300.017
Ben RoethlisbergerBen Roethlisberger11/24/2016PITPIT@ IND
@
146.0142070.022111.1315.000.000
Kirk CousinsKirk Cousins11/20/2016WASWASvs. GB
vs.
145.8213070.037512.5310.000.0211
Matt RyanMatt Ryan11/3/2016ATLATL@ TB
@
144.7253473.534410.1411.800.0219
Matt RyanMatt Ryan12/18/2016ATLATLvs. SF
vs.
144.5172373.928612.428.700.010
Matt RyanMatt Ryan10/2/2016ATLATLvs. CAR
vs.
142.0283775.750313.6410.812.7322
Dak PrescottDak Prescott11/6/2016DALDAL@ CLE
@
141.8212777.82479.1311.100.000
Trevor SiemianTrevor Siemian10/2/2016DENDEN@ TB
@
141.75771.4689.7114.300.0320
Tom BradyTom Brady10/16/2016NENEvs. CIN
vs.
140.0293582.937610.738.600.0318
Matt RyanMatt Ryan1/1/2017ATLATLvs. NO
vs.
139.9273675.03319.2411.100.018
Matthew StaffordMatthew Stafford10/16/2016DETDETvs. LA
vs.
139.8233174.22708.7412.900.015
Drew BreesDrew Brees11/27/2016NONOvs. LA
vs.
139.6283677.83108.6411.100.0214
Philip RiversPhilip Rivers9/18/2016SDSDvs. JAX
vs.
138.9172470.82209.2416.700.0313
Russell WilsonRussell Wilson11/7/2016SEASEAvs. BUF
vs.
137.0202676.928210.827.700.0437
Tom BradyTom Brady10/30/2016NENE@ BUF
@
137.0223366.73159.5412.100.0422
Aaron RodgersAaron Rodgers12/24/2016GBGBvs. MIN
vs.
136.6283873.73479.1410.500.0439
Jimmy GaroppoloJimmy Garoppolo9/18/2016NENEvs. MIA
vs.
135.4182669.22328.9311.500.000
Nick FolesNick Foles10/30/2016KCKC@ IND
@
135.2162272.722310.129.100.0216
Matthew StaffordMatthew Stafford10/9/2016DETDETvs. PHI
vs.
135.0192576.01807.2312.000.0416
Tony RomoTony Romo1/1/2017DALDAL@ PHI
@
134.43475.0297.3125.000.000

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