| NAME | SEASON | TM | GP | PTS | RUSH YDS | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Derrick Henry | 2021 |  TEN | 6 | 62 | 783 | 162 | 4.8 | 130.5 | 10 | 138 | 16 | 18 | 8.6 | 23.0 | 0 |
 | Austin Ekeler | 2021 |  LAC | 6 | 44 | 356 | 73 | 4.9 | 59.3 | 4 | 242 | 27 | 32 | 9.0 | 40.3 | 3 |
 | Ezekiel Elliott | 2021 |  DAL | 6 | 36 | 521 | 102 | 5.1 | 86.8 | 5 | 105 | 16 | 20 | 6.6 | 17.5 | 1 |
 | Aaron Jones | 2021 |  GB | 6 | 36 | 385 | 83 | 4.6 | 64.2 | 2 | 166 | 21 | 23 | 7.9 | 27.7 | 4 |
 | Kareem Hunt | 2021 |  CLE | 6 | 32 | 361 | 69 | 5.2 | 60.2 | 5 | 161 | 20 | 24 | 8.1 | 26.8 | 0 |
 | Cordarrelle Patterson | 2021 |  ATL | 5 | 30 | 173 | 41 | 4.2 | 34.6 | 1 | 295 | 25 | 31 | 11.8 | 59.0 | 4 |
 | Adam Thielen | 2021 |  MIN | 6 | 30 | 2 | 1 | 2.0 | 0.3 | 0 | 393 | 37 | 50 | 10.6 | 65.5 | 5 |
 | Tyreek Hill | 2021 |  KC | 6 | 30 | 45 | 4 | 11.3 | 7.5 | 0 | 592 | 46 | 63 | 12.9 | 98.7 | 5 |
 | James Conner | 2021 |  ARI | 6 | 30 | 272 | 79 | 3.4 | 45.3 | 5 | 34 | 5 | 5 | 6.8 | 5.7 | 0 |
 | Sam Darnold | 2021 |  CAR | 6 | 30 | 110 | 26 | 4.2 | 18.3 | 5 | 0 | 0 | 0 | 0.0 | 0 | |
 | Darrell Henderson | 2021 |  LAR | 5 | 30 | 372 | 81 | 4.6 | 74.4 | 4 | 119 | 12 | 16 | 9.9 | 23.8 | 1 |
 | Marquise Brown | 2021 |  BAL | 6 | 30 | 5 | 1 | 5.0 | 0.8 | 0 | 486 | 32 | 43 | 15.2 | 81.0 | 5 |
 | Jalen Hurts | 2021 |  PHI | 6 | 30 | 300 | 53 | 5.7 | 50.0 | 5 | 0 | 0 | 1 | 0.0 | 0 | |
 | Jonathan Taylor | 2021 |  IND | 6 | 30 | 472 | 87 | 5.4 | 78.7 | 4 | 210 | 15 | 18 | 14.0 | 35.0 | 1 |
 | James Robinson | 2021 |  JAX | 6 | 30 | 460 | 84 | 5.5 | 76.7 | 5 | 116 | 17 | 22 | 6.8 | 19.3 | 0 |
 | Antonio Brown | 2021 |  TB | 5 | 24 | 6 | 1 | 6.0 | 1.2 | 0 | 418 | 29 | 42 | 14.4 | 83.6 | 4 |
 | Latavius Murray | 2021 | BAL | 6 | 24 | 212 | 59 | 3.6 | 35.3 | 4 | 25 | 4 | 5 | 6.3 | 4.2 | 0 |
 | Emmanuel Sanders | 2021 |  BUF | 6 | 24 | 7 | 1 | 7.0 | 1.2 | 0 | 413 | 24 | 39 | 17.2 | 68.8 | 4 |
 | Alvin Kamara | 2021 |  NO | 5 | 24 | 368 | 94 | 3.9 | 73.6 | 1 | 113 | 15 | 22 | 7.5 | 22.6 | 3 |
 | Joe Mixon | 2021 |  CIN | 6 | 24 | 480 | 111 | 4.3 | 80.0 | 3 | 90 | 13 | 16 | 6.9 | 15.0 | 1 |
 | Darrel Williams | 2021 | KC | 6 | 24 | 161 | 47 | 3.4 | 26.8 | 4 | 72 | 10 | 14 | 7.2 | 12.0 | 0 |
 | Nick Chubb | 2021 | CLE | 5 | 24 | 523 | 90 | 5.8 | 104.6 | 4 | 35 | 5 | 5 | 7.0 | 7.0 | 0 |
 | Josh Jacobs | 2021 |  LV | 4 | 24 | 175 | 54 | 3.2 | 43.8 | 4 | 71 | 11 | 13 | 6.5 | 17.8 | 0 |
 | Deebo Samuel | 2021 |  SF | 5 | 24 | 22 | 6 | 3.7 | 4.4 | 1 | 548 | 31 | 52 | 17.7 | 109.6 | 3 |
 | CeeDee Lamb | 2021 | DAL | 6 | 24 | 18 | 4 | 4.5 | 3.0 | 0 | 497 | 33 | 49 | 15.1 | 82.8 | 4 |