The San Francisco 49ers have a record of 34-29 against the spread in the regular season since November 1, 2022.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 11/13/2022 | 0-1 | -361 | vs | +284 | W 22-16 | -8 | -2 (N) | 45.5 | -7.5 (U) | 2 | 22 | 387 | 238 | 52.9 | 100.0 | ||
| 2 | | 49ers | 11/21/2022 | 1-0 | -442 | @ | +341 | W 38-10 | -9.5 | +18.5 (Y) | 43 | +5 (O) | 5 | 21 | 387 | 314 | 54.5 | |||
| 3 | | 49ers | 11/27/2022 | 1-0 | -426 | vs | +325 | W 13-0 | -8.5 | +4.5 (Y) | 43.5 | -30.5 (U) | 1 | 21 | 317 | 260 | 38.5 | 50.0 | ||
| 4 | | 49ers | 12/4/2022 | 1-0 | -233 | vs | +191 | W 33-17 | -5 | +11 (Y) | 46 | +4 (O) | 3 | 24 | 351 | 308 | 42.1 | 50.0 | ||
| 5 | | 49ers | 12/11/2022 | 1-0 | -182 | vs | +152 | W 35-7 | -3.5 | +24.5 (Y) | 38.5 | +3.5 (O) | 5 | 24 | 404 | 322 | 44.4 | 50.0 | ||
| 6 | | 49ers | 12/15/2022 | 1-0 | -181 | @ | +152 | W 21-13 | -3 | +5 (Y) | 42.5 | -8.5 (U) | 3 | 15 | 381 | 277 | 46.2 | |||
| 7 | | 49ers | 12/24/2022 | 1-0 | -299 | vs | +240 | W 37-20 | -6.5 | +10.5 (Y) | 37 | +20 (O) | 4 | 14 | 371 | 349 | 36.4 | 50.0 | ||
| 8 | | 49ers | 1/1/2023 | 0-1 | -472 | @ | +359 | W 37-34 | -10 | -7 (N) | 41 | +30 (O) | 4 | 27 | 454 | 500 | 50.0 | |||
| 9 | | 49ers | 1/8/2023 | 1-0 | -1057 | vs | +693 | W 38-13 | -14.5 | +10.5 (Y) | 39.5 | +11.5 (O) | 5 | 21 | 311 | 255 | 46.2 | 0.0 | ||
| 10 | | 49ers | 9/10/2023 | 1-0 | -121 | @ | +102 | W 30-7 | -1.5 | +21.5 (Y) | 41.5 | -4.5 (U) | 3 | 22 | 391 | 239 | 46.2 | 100.0 | ||
| 11 | | 49ers | 9/17/2023 | 0-1 | -343 | @ | +273 | W 30-23 | -7.5 | -0.5 (N) | 45 | +8 (O) | 3 | 21 | 365 | 386 | 22.2 | |||
| 12 | | 49ers | 9/21/2023 | 1-0 | -573 | vs | +426 | W 30-12 | -10.5 | +7.5 (Y) | 43.5 | -1.5 (U) | 3 | 26 | 441 | 150 | 56.3 | |||
| 13 | | 49ers | 10/1/2023 | 1-0 | -1106 | vs | +692 | W 35-16 | -14.5 | +4.5 (Y) | 44 | +7 (O) | 5 | 30 | 395 | 362 | 60.0 | 100.0 | ||
| 14 | | 49ers | 10/8/2023 | 1-0 | -182 | vs | +154 | W 42-10 | -3.5 | +28.5 (Y) | 45.5 | +6.5 (O) | 6 | 25 | 421 | 197 | 54.5 | 0.0 | ||
| 15 | | 49ers | 10/15/2023 | 0-1 | -507 | @ | +379 | L 17-19 | -9.5 | -11.5 (N) | 36 | 0 (P) | 2 | 15 | 215 | 334 | 25.0 | |||
| 16 | | 49ers | 10/23/2023 | 0-1 | -315 | @ | +251 | L 17-22 | -7 | -12 (N) | 44 | -5 (U) | 2 | 19 | 325 | 452 | 55.6 | 100.0 | ||
| 17 | | 49ers | 10/29/2023 | 0-1 | -211 | vs | +173 | L 17-31 | -4 | -18 (N) | 44 | +4 (O) | 2 | 24 | 460 | 400 | 55.6 | |||
| 18 | | 49ers | 11/12/2023 | 1-0 | -172 | @ | +144 | W 34-3 | -3 | +28 (Y) | 44.5 | -7.5 (U) | 4 | 20 | 437 | 221 | 33.3 | 50.0 | ||
| 19 | | 49ers | 11/19/2023 | 0-1 | -831 | vs | +567 | W 27-14 | -13.5 | -0.5 (N) | 41.5 | -0.5 (U) | 3 | 22 | 420 | 287 | 40.0 | 0.0 | ||
| 20 | | 49ers | 11/23/2023 | 1-0 | -334 | @ | +260 | W 31-13 | -7 | +11 (Y) | 43 | +1 (O) | 4 | 23 | 377 | 220 | 45.5 | |||
| 21 | | 49ers | 12/3/2023 | 1-0 | -158 | @ | +134 | W 42-19 | -3 | +20 (Y) | 46.5 | +14.5 (O) | 6 | 24 | 456 | 333 | 72.7 | 100.0 | ||
| 22 | | 49ers | 12/10/2023 | 0-1 | -1099 | vs | +683 | W 28-16 | -14.5 | -2.5 (N) | 44.5 | -0.5 (U) | 4 | 19 | 527 | 324 | 54.5 | |||
| 23 | | 49ers | 12/17/2023 | 1-0 | -771 | @ | +529 | W 45-29 | -12.5 | +3.5 (Y) | 48 | +26 (O) | 6 | 24 | 406 | 436 | 57.1 | |||
| 24 | | 49ers | 12/25/2023 | 0-1 | -296 | vs | +238 | L 19-33 | -6.5 | -20.5 (N) | 47 | +5 (O) | 2 | 21 | 429 | 343 | 42.9 | 33.3 | ||
| 25 | | 49ers | 12/31/2023 | 1-0 | -967 | @ | +633 | W 27-10 | -14 | +3 (Y) | 48.5 | -11.5 (U) | 3 | 28 | 408 | 225 | 44.4 | 0.0 | ||
| Average | 0.9 | 3.1 | 21.8 | 376.3 | 319.2 | 47.1 | 0.0 | |||||||||||||
| Total | 34-29 | 197 | 1,372 | 23,705 | 20,109 | 47.1 | 54.1 | |||||||||||||
SF
LAC
ARI
NO
MIA
TB
SEA
WAS
LV
PIT
LAR
NYG
DAL
CLE
MIN
CIN
JAX
PHI
BALStatMuse has team, game-level data for spread records going back to the 1979 season.
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More 49ers Stats
Team Leaders 
PASS
789
Purdy
RUSH
166
McCaffrey
REC
174
Kittle
Team Rankings
PPG
32.7
2nd
OPP PPG
16.7
3rd
RUSH YDS/G
136.3
6th
PASS YDS/G
263.0
9th
DEN
ATL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
| NFC North | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
| NFC South | W | L | T | PCT |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
| NFC West | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 |
Lions
Bears
Packers
Panthers| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 0 | 0 | 1.000 | |
1 | 2 | 0 | .333 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
| AFC North | W | L | T | PCT |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
2 | 1 | 0 | .667 | |
| AFC South | W | L | T | PCT |
2 | 1 | 0 | .667 | |
1 | 2 | 0 | .333 | |
0 | 3 | 0 | .000 | |
0 | 3 | 0 | .000 | |
| AFC West | W | L | T | PCT |
3 | 0 | 0 | 1.000 | |
3 | 0 | 0 | 1.000 | |
2 | 1 | 0 | .667 | |
0 | 3 | 0 | .000 |
Bills
Jets
Patriots
Colts
Titans
Texans
Chiefs