The Buffalo Bills have a 33-24 record against the spread against the AFC West since September 11, 2001.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 10/28/2001 | 1-0 | @ | L 24-27 | +7 | +4 (Y) | 39 | +12 (O) | 3 | 22 | 396 | 338 | 35.7 | 100.0 | ||||
| 2 | | Bills | 11/18/2001 | 1-0 | vs | L 20-23 | +3.5 | +0.5 (Y) | 39 | +4 (O) | 2 | 25 | 372 | 246 | 30.0 | 100.0 | ||||
| 3 | | Bills | 9/22/2002 | 1-0 | @ | L 23-28 | +7.5 | +2.5 (Y) | 47 | +4 (O) | 3 | 17 | 291 | 342 | 42.9 | |||||
| 4 | | Bills | 10/6/2002 | 0-1 | vs | L 31-49 | +3 | -15 (N) | 53 | +27 (O) | 4 | 29 | 479 | 495 | 46.7 | 100.0 | ||||
| 5 | | Bills | 11/17/2002 | 1-0 | @ | L 16-17 | +3 | +2 (Y) | 51 | -18 (U) | 1 | 21 | 344 | 320 | 53.8 | |||||
| 6 | | Bills | 12/15/2002 | 1-0 | vs | W 20-13 | -3 | +4 (Y) | 42.5 | -9.5 (U) | 2 | 17 | 256 | 308 | 16.7 | |||||
| 7 | | Bills | 10/26/2003 | 0-1 | @ | L 5-38 | +6.5 | -26.5 (N) | 43.5 | -0.5 (U) | 0 | 15 | 266 | 375 | 27.3 | 0.0 | ||||
| 8 | | Bills | 9/19/2004 | 1-0 | @ | L 10-13 | +3.5 | +0.5 (Y) | 38 | -15 (U) | 1 | 14 | 243 | 273 | 30.8 | 66.7 | ||||
| 9 | | Bills | 10/23/2005 | 0-1 | @ | L 17-38 | +3 | -18 (N) | 41 | +14 (O) | 2 | 15 | 210 | 416 | 30.0 | 0.0 | ||||
| 10 | | Bills | 11/13/2005 | 1-0 | vs | W 14-3 | -2.5 | +8.5 (Y) | 41 | -24 (U) | 2 | 9 | 209 | 316 | 23.1 | 0.0 | ||||
| 11 | | Bills | 11/20/2005 | 0-1 | @ | L 10-48 | +11.5 | -26.5 (N) | 42.5 | +15.5 (O) | 1 | 12 | 202 | 478 | 23.1 | 50.0 | ||||
| 12 | | Bills | 12/17/2005 | 0-1 | vs | L 17-28 | +9 | -2 (N) | 34.5 | +10.5 (O) | 2 | 17 | 272 | 437 | 33.3 | 100.0 | ||||
| 13 | | Bills | 12/3/2006 | 1-0 | +220 | vs | -280 | L 21-24 | +6 | +3 (Y) | 41 | +4 (O) | 3 | 16 | 230 | 335 | 47.1 | |||
| 14 | | Bills | 9/9/2007 | 1-0 | +150 | vs | -170 | L 14-15 | +3 | +2 (Y) | 37 | -8 (U) | 2 | 13 | 184 | 470 | 27.3 | 100.0 | ||
| 15 | | Bills | 9/21/2008 | 0-1 | -525 | vs | +425 | W 24-23 | -9.5 | -8.5 (N) | 36.5 | +10.5 (O) | 3 | 25 | 378 | 247 | 41.7 | 100.0 | ||
| 16 | | Bills | 10/19/2008 | 1-0 | -115 | vs | -110 | W 23-14 | +2 | +11 (Y) | 46.5 | -9.5 (U) | 2 | 22 | 370 | 263 | 46.2 | |||
| 17 | | Bills | 11/23/2008 | 1-0 | -160 | @ | +140 | W 54-31 | -3 | +20 (Y) | 43 | +42 (O) | 6 | 27 | 444 | 462 | 28.6 | 50.0 | ||
| 18 | | Bills | 12/21/2008 | 1-0 | +235 | @ | -275 | W 30-23 | +6 | +13 (Y) | 45 | +8 (O) | 3 | 20 | 275 | 532 | 40.0 | |||
| 19 | | Bills | 12/13/2009 | 1-0 | -150 | @ | +140 | W 16-10 | -2.5 | +3.5 (Y) | 37.5 | -11.5 (U) | 1 | 13 | 273 | 354 | 25.0 | |||
| 20 | | Bills | 10/31/2010 | 1-0 | +265 | @ | -325 | L 10-13 | +7 | +4 (Y) | 45.5 | -22.5 (U) | 1 | 23 | 328 | 414 | 47.8 | 50.0 | ||
| 21 | | Bills | 9/11/2011 | 1-0 | +180 | @ | -210 | W 41-7 | +4 | +38 (Y) | 40 | +8 (O) | 5 | 23 | 364 | 213 | 50.0 | |||
| 22 | | Bills | 9/18/2011 | 0-1 | -200 | vs | +175 | W 38-35 | -4 | -1 (N) | 41 | +32 (O) | 5 | 34 | 481 | 454 | 36.4 | 100.0 | ||
| 23 | | Bills | 12/11/2011 | 0-1 | +280 | @ | -340 | L 10-37 | +7 | -20 (N) | 48.5 | -1.5 (U) | 1 | 17 | 281 | 366 | 36.4 | 0.0 | ||
| 24 | | Bills | 12/24/2011 | 1-0 | +130 | vs | -150 | W 40-14 | +3 | +29 (Y) | 42.5 | +11.5 (O) | 4 | 14 | 351 | 285 | 16.7 | |||
| 25 | | Bills | 9/16/2012 | 1-0 | -165 | vs | +145 | W 35-17 | -3 | +15 (Y) | 45 | +7 (O) | 5 | 15 | 379 | 422 | 41.7 | |||
| Average | 1.0 | 2.8 | 20.6 | 348.3 | 349.9 | 41.8 | 0.0 | |||||||||||||
| Total | 33-24 | 159 | 1,176 | 19,854 | 19,942 | 41.8 | 58.9 | |||||||||||||
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 1 | .700 | |
2 | 3 | 0 | .400 | |
2 | 3 | 0 | .400 | |
1 | 3 | 1 | .300 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
1 | 4 | 0 | .200 | |
| NFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 |
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Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 1 | 0 | .800 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
0 | 5 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
0 | 5 | 0 | .000 |
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