The Buffalo Bills had a 0-6 record in the regular season and playoffs against the NFC between November 22, 1918 and November 22, 1971.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/27/1970 | 0-1 | vs | L 0-19 | .000 | 0 | 12 | 177 | 364 | ||||
| 2 | | Bills | 11/22/1970 | 0-1 | @ | L 13-31 | .000 | 2 | 14 | 253 | 241 | ||||
| 3 | | Bills | 12/6/1970 | 0-1 | @ | L 6-20 | .000 | 0 | 13 | 180 | 270 | ||||
| 4 | | Bills | 9/19/1971 | 0-1 | vs | L 37-49 | .000 | 5 | 18 | 401 | 371 | ||||
| 5 | | Bills | 10/3/1971 | 0-1 | @ | L 0-19 | .000 | 0 | 7 | 64 | 326 | ||||
| 6 | | Bills | 10/31/1971 | 0-1 | vs | L 23-28 | .000 | 3 | 19 | 309 | 305 | ||||
| Average | .000 | 1.7 | 13.8 | 230.7 | 312.8 | ||||||||||
| Total | 0-6 | .000 | 10 | 83 | 1,384 | 1,877 |
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Team Leaders 
PASS
1,793
Allen
RUSH
707
Cook
REC
401
Kincaid
Team Rankings
PPG
33.3
1st
OPP PPG
25.9
24th
RUSH YDS/G
148.4
3rd
PASS YDS/G
256.1
9th
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 5 | 0 | .375 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 1 | 0 | .857 | |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
5 | 3 | 0 | .625 | |
| NFC South | W | L | T | PCT |
3 | 4 | 0 | .429 | |
3 | 5 | 0 | .375 | |
3 | 5 | 0 | .375 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
4 | 4 | 0 | .500 | |
3 | 5 | 0 | .375 |
Eagles
Commanders
Lions
Bears
Packers
Panthers
Buccaneers
Falcons
Saints
49ers
Seahawks
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
6 | 1 | 0 | .857 | |
5 | 3 | 0 | .625 | |
2 | 6 | 0 | .250 | |
1 | 6 | 0 | .143 | |
| AFC North | W | L | T | PCT |
6 | 2 | 0 | .750 | |
5 | 2 | 0 | .714 | |
5 | 3 | 0 | .625 | |
4 | 4 | 0 | .500 | |
| AFC South | W | L | T | PCT |
5 | 2 | 0 | .714 | |
2 | 5 | 0 | .286 | |
2 | 6 | 0 | .250 | |
1 | 7 | 0 | .125 | |
| AFC West | W | L | T | PCT |
6 | 2 | 0 | .750 | |
5 | 2 | 0 | .714 | |
4 | 4 | 0 | .500 | |
0 | 7 | 0 | .000 |
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