The Carolina Panthers are 25-41-1 against the AFC in the regular-season and playoffs on the road all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Panthers | 9/10/1995 | 0-1 |  CAR | @ |  BUF | L 9-31 | .000 | 0 | 6 | 113 | 348 | 11.8 | |
| 2 | | Panthers | 10/29/1995 | 1-0 | CAR | @ |  NE | W 20-17 | 1.000 | 2 | 23 | 434 | 326 | 52.2 | 100.0 |
| 3 | | Panthers | 9/29/1996 | 0-1 | CAR | @ |  JAX | L 14-24 | .000 | 2 | 21 | 272 | 378 | 38.5 | |
| 4 | | Panthers | 11/24/1996 | 1-0 | CAR | @ |  HOU | W 31-6 | 1.000 | 4 | 12 | 254 | 271 | 40.0 | |
| 5 | | Panthers | 9/14/1997 | 1-0 | CAR | @ |  SD | W 26-7 | 1.000 | 2 | 21 | 279 | 251 | 41.2 | 0.0 |
| 6 | | Panthers | 11/9/1997 | 0-1 | CAR | @ |  DEN | L 0-34 | .000 | 0 | 7 | 147 | 393 | 23.1 | |
| 7 | | Panthers | 11/29/1998 | 0-1 | CAR | @ |  NYJ | L 21-48 | .000 | 3 | 15 | 216 | 456 | 30.0 | 100.0 |
| 8 | | Panthers | 12/27/1998 | 1-0 | CAR | @ |  IND | W 27-19 | 1.000 | 3 | 17 | 332 | 279 | 37.5 | 50.0 |
| 9 | | Panthers | 11/21/1999 | 1-0 | CAR | @ |  CLE | W 31-17 | 1.000 | 4 | 22 | 330 | 306 | 50.0 | 100.0 |
| 10 | | Panthers | 12/26/1999 | 0-1 | CAR | @ |  PIT | L 20-30 | .000 | 3 | 17 | 375 | 293 | 30.0 | 33.3 |
| 11 | | Panthers | 12/10/2000 | 0-1 | CAR | @ |  KC | L 14-15 | .000 | 2 | 21 | 257 | 453 | 25.0 | |
| 12 | | Panthers | 12/24/2000 | 0-1 | CAR | @ |  OAK | L 9-52 | .000 | 0 | 19 | 297 | 409 | 50.0 | |
| 13 | | Panthers | 11/4/2001 | 0-1 | CAR | @ |  MIA | L 6-23 | .000 | 0 | 12 | 281 | 337 | 15.4 | 0.0 |
| 14 | | Panthers | 12/9/2001 | 0-1 | CAR | @ | BUF | L 24-25 | .000 | 3 | 17 | 231 | 369 | 22.2 | 0.0 |
| 15 | | Panthers | 12/1/2002 | 1-0 | CAR | @ | CLE | W 13-6 | 1.000 | 1 | 11 | 234 | 258 | 33.3 | 100.0 |
| 16 | | Panthers | 12/15/2002 | 0-1 | CAR | @ | PIT | L 14-30 | .000 | 2 | 11 | 131 | 332 | 35.7 | 0.0 |
| 17 | | Panthers | 10/12/2003 | 1-0 | CAR | @ | IND | W 23-20 | 1.000 | 2 | 17 | 341 | 369 | 33.3 | |
| 18 | | Panthers | 11/2/2003 | 0-1 | CAR | @ |  HOU | L 10-14 | .000 | 1 | 21 | 367 | 267 | 44.4 | 100.0 |
| 19 | | Panthers | 2/1/2004 | 0-1 | CAR | @ | NE | L 29-32 | .000 | 4 | 17 | 387 | 481 | 33.3 | |
| 20 | | Panthers | 9/19/2004 | 1-0 | CAR | @ | KC | W 28-17 | 1.000 | 4 | 23 | 358 | 281 | 42.9 | |
| 21 | | Panthers | 10/10/2004 | 0-1 | CAR | @ | DEN | L 17-20 | .000 | 2 | 12 | 227 | 434 | 41.7 | |
| 22 | | Panthers | 9/25/2005 | 0-1 | CAR | @ | MIA | L 24-27 | .000 | 3 | 23 | 299 | 315 | 46.2 | |
| 23 | | Panthers | 11/27/2005 | 1-0 | CAR | @ | BUF | W 13-9 | 1.000 | 1 | 19 | 295 | 216 | 64.3 | |
| 24 | | Panthers | 10/15/2006 | 1-0 | CAR | @ |  BAL | W 23-21 | 1.000 | 2 | 20 | 414 | 292 | 46.7 | |
| 25 | | Panthers | 10/22/2006 | 0-1 | CAR | @ |  CIN | L 14-17 | .000 | 2 | 17 | 277 | 342 | 18.2 | |
| Average | .381 | 2.1 | 17.9 | 293.9 | 338.4 | 37.6 | 1.3 | ||||||||
| Total | 25-41-1 | .381 | 138 | 1,200 | 19,688 | 22,673 | 37.6 | 50.6 | |||||||
More Panthers Stats
Team Rankings
PPG
19.3
27th
OPP PPG
24.0
20th
RUSH YDS/G
136.9
5th
PASS YDS/G
197.6
30th
2025 Division Standings
| TEAM | W | L | T | PCT |
|---|---|---|---|---|
 Buccaneers | 6 | 2 | 0 | .750 |
| Panthers | 4 | 4 | 0 | .500 |
 Falcons | 3 | 4 | 0 | .429 |
 Saints | 1 | 7 | 0 | .125 |
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