The San Francisco 49ers have a record of 40-26 against the AFC East in the regular-season and playoffs all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10/31/1971 | 1-0 |  SF | vs |  NE | W 27-10 | 1.000 | 3 | 13 | 247 | 246 | ||
| 2 | | 49ers | 11/28/1971 | 1-0 | SF | @ |  NYJ | W 24-21 | 1.000 | 3 | 20 | 351 | 393 | ||
| 3 | | 49ers | 9/24/1972 | 0-1 | SF | @ |  BUF | L 20-27 | .000 | 2 | 10 | 202 | 233 | ||
| 4 | | 49ers | 11/12/1972 | 1-0 | SF | vs |  BAL | W 24-21 | 1.000 | 3 | 19 | 310 | 297 | ||
| 5 | | 49ers | 9/16/1973 | 0-1 | SF | @ |  MIA | L 13-21 | .000 | 1 | 16 | 252 | 279 | ||
| 6 | | 49ers | 10/26/1975 | 0-1 | SF | @ | NE | L 16-24 | .000 | 2 | 14 | 243 | 306 | ||
| 7 | | 49ers | 10/3/1976 | 1-0 | SF | vs | NYJ | W 17-6 | 1.000 | 2 | 16 | 247 | 261 | ||
| 8 | | 49ers | 9/25/1977 | 0-1 | SF | vs | MIA | L 15-19 | .000 | 2 | 13 | 280 | 361 | ||
| 9 | | 49ers | 9/21/1980 | 1-0 | SF | @ | NYJ | W 37-27 | 1.000 | 5 | 24 | 376 | 460 | ||
| 10 | | 49ers | 11/16/1980 | 0-1 | SF | @ | MIA | L 13-17 | .000 | 2 | 20 | 289 | 378 | ||
| 11 | | 49ers | 11/30/1980 | 1-0 | SF | vs | NE | W 21-17 | 1.000 | 3 | 15 | 229 | 343 | ||
| 12 | | 49ers | 12/21/1980 | 0-1 | SF | vs | BUF | L 13-18 | .000 | 2 | 19 | 298 | 267 | ||
| 13 | | 49ers | 10/2/1983 | 1-0 | SF | @ | NE | W 33-13 | 1.000 | 3 | 29 | 426 | 295 | ||
| 14 | | 49ers | 10/30/1983 | 0-1 | SF | vs | NYJ | L 13-27 | .000 | 1 | 17 | 312 | 364 | ||
| 15 | | 49ers | 11/6/1983 | 0-1 | SF | vs | MIA | L 17-20 | .000 | 2 | 20 | 394 | 316 | ||
| 16 | | 49ers | 12/11/1983 | 1-0 | SF | @ | BUF | W 23-10 | 1.000 | 2 | 19 | 310 | 303 | ||
| 17 | | 49ers | 1/20/1985 | 1-0 | SF | vs | MIA | W 38-16 | 1.000 | 5 | 31 | 537 | 314 | ||
| 18 | | 49ers | 9/28/1986 | 1-0 | SF | @ | MIA | W 31-16 | 1.000 | 4 | 16 | 314 | 437 | ||
| 19 | | 49ers | 10/5/1986 | 1-0 | SF | vs |  IND | W 35-14 | 1.000 | 5 | 16 | 358 | 323 | ||
| 20 | | 49ers | 12/7/1986 | 1-0 | SF | vs | NYJ | W 24-10 | 1.000 | 3 | 27 | 432 | 199 | ||
| 21 | | 49ers | 12/14/1986 | 1-0 | SF | @ | NE | W 29-24 | 1.000 | 3 | 23 | 400 | 267 | ||
| 22 | | 49ers | 9/10/1989 | 1-0 | SF | @ | IND | W 30-24 | 1.000 | 3 | 24 | 404 | 344 | ||
| 23 | | 49ers | 10/22/1989 | 1-0 | SF | vs | NE | W 37-20 | 1.000 | 5 | 28 | 494 | 325 | ||
| 24 | | 49ers | 10/29/1989 | 1-0 | SF | @ | NYJ | W 23-10 | 1.000 | 2 | 20 | 399 | 251 | ||
| 25 | | 49ers | 12/17/1989 | 1-0 | SF | vs | BUF | W 21-10 | 1.000 | 3 | 18 | 283 | 301 | ||
| Average | .606 | 2.9 | 20.4 | 353.7 | 321.2 | ||||||||||
| Total | 40-26 | .606 | 192 | 1,348 | 23,345 | 21,196 | |||||||||
More 49ers Stats
Team Rankings
PPG
22.9
13th
OPP PPG
25.6
29th
RUSH YDS/G
127.2
12th
PASS YDS/G
260.2
4th
Cardinals 
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JAX 
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NFL 2024 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 14 | 3 | 0 | .824 |
 Commanders | 12 | 5 | 0 | .706 |
| NFC North | W | L | T | PCT |
 Lions | 15 | 2 | 0 | .882 |
 Vikings | 14 | 3 | 0 | .824 |
| NFC South | W | L | T | PCT |
 Buccaneers | 10 | 7 | 0 | .588 |
 Falcons | 8 | 9 | 0 | .471 |
| NFC West | W | L | T | PCT |
 Rams | 10 | 7 | 0 | .588 |
 Seahawks | 10 | 7 | 0 | .588 |
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