The New England Patriots have a 5-10 record in the regular-season and playoffs versus the 49ers all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Patriots | 10/31/1971 | 0-1 |  NE | @ |  SF | L 10-27 | .000 | 1 | 11 | 246 | 247 | ||
| 2 | | Patriots | 10/26/1975 | 1-0 | NE | vs | SF | W 24-16 | 1.000 | 3 | 20 | 306 | 243 | ||
| 3 | | Patriots | 11/30/1980 | 0-1 | NE | @ | SF | L 17-21 | .000 | 2 | 16 | 343 | 229 | ||
| 4 | | Patriots | 10/2/1983 | 0-1 | NE | vs | SF | L 13-33 | .000 | 2 | 14 | 295 | 426 | ||
| 5 | | Patriots | 12/14/1986 | 0-1 | NE | vs | SF | L 24-29 | .000 | 3 | 16 | 267 | 400 | ||
| 6 | | Patriots | 10/22/1989 | 0-1 | NE | @ | SF | L 20-37 | .000 | 2 | 19 | 325 | 494 | ||
| 7 | | Patriots | 10/11/1992 | 0-1 | NE | vs | SF | L 12-24 | .000 | 1 | 17 | 227 | 411 | 35.7 | |
| 8 | | Patriots | 9/17/1995 | 0-1 | NE | @ | SF | L 3-28 | .000 | 0 | 18 | 302 | 363 | 50.0 | 25.0 |
| 9 | | Patriots | 12/20/1998 | 1-0 | NE | vs | SF | W 24-21 | 1.000 | 3 | 20 | 332 | 410 | 35.7 | 100.0 |
| 10 | | Patriots | 1/2/2005 | 1-0 | NE | vs | SF | W 21-7 | 1.000 | 3 | 23 | 405 | 318 | 14.3 | 50.0 |
| 11 | | Patriots | 10/5/2008 | 1-0 | NE | @ | SF | W 30-21 | 1.000 | 3 | 25 | 377 | 199 | 47.1 | 100.0 |
| 12 | | Patriots | 12/16/2012 | 0-1 | NE | vs | SF | L 34-41 | .000 | 4 | 32 | 520 | 388 | 13.3 | 83.3 |
| 13 | | Patriots | 11/20/2016 | 1-0 | NE | @ | SF | W 30-17 | 1.000 | 4 | 28 | 444 | 299 | 50.0 | 100.0 |
| 14 | | Patriots | 10/25/2020 | 0-1 | NE | vs | SF | L 6-33 | .000 | 0 | 17 | 241 | 467 | 16.7 | |
| 15 | | Patriots | 9/29/2024 | 0-1 | NE | @ | SF | L 13-30 | .000 | 1 | 12 | 216 | 431 | 31.3 | 33.3 |
| Average | .333 | 2.1 | 19.2 | 323.1 | 355.0 | ||||||||||
| Total | 5-10 | .333 | 32 | 288 | 4,846 | 5,325 |
More Patriots Stats
Team Rankings
PPG
25.0
12th
OPP PPG
20.2
9th
RUSH YDS/G
95.2
27th
PASS YDS/G
252.2
7th
Bills 
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CLE 
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NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 1 | 0 | .800 |
 Commanders | 3 | 2 | 0 | .600 |
| NFC North | W | L | T | PCT |
 Lions | 4 | 1 | 0 | .800 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 4 | 1 | 0 | .800 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
| 49ers | 4 | 1 | 0 | .800 |
 Seahawks | 3 | 2 | 0 | .600 |
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ARI 
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BAL 
