The New England Patriots have a 20-7 record against the Bills in the regular season and playoffs on the road since September 11, 2001.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Patriots | 12/16/2001 | 1-0 | @ | W 12-9 | 1.000 | 0 | 17 | 335 | 310 | 41.2 | |||
| 2 | | Patriots | 11/3/2002 | 1-0 | @ | W 38-7 | 1.000 | 5 | 23 | 422 | 331 | 66.7 | 50.0 | ||
| 3 | | Patriots | 9/7/2003 | 0-1 | @ | L 0-31 | .000 | 0 | 16 | 239 | 322 | 40.0 | 0.0 | ||
| 4 | | Patriots | 10/3/2004 | 1-0 | @ | W 31-17 | 1.000 | 4 | 21 | 397 | 337 | 45.5 | |||
| 5 | | Patriots | 12/11/2005 | 1-0 | @ | W 35-7 | 1.000 | 5 | 32 | 494 | 183 | 68.8 | 0.0 | ||
| 6 | | Patriots | 10/22/2006 | 1-0 | @ | W 28-6 | 1.000 | 4 | 18 | 265 | 255 | 53.3 | |||
| 7 | | Patriots | 11/18/2007 | 1-0 | @ | W 56-10 | 1.000 | 8 | 30 | 510 | 229 | 72.7 | 100.0 | ||
| 8 | | Patriots | 12/28/2008 | 1-0 | @ | W 13-0 | 1.000 | 1 | 16 | 241 | 276 | 20.0 | 100.0 | ||
| 9 | | Patriots | 12/20/2009 | 1-0 | @ | W 17-10 | 1.000 | 2 | 19 | 224 | 241 | 41.7 | |||
| 10 | | Patriots | 12/26/2010 | 1-0 | @ | W 34-3 | 1.000 | 4 | 20 | 348 | 369 | 47.1 | 0.0 | ||
| 11 | | Patriots | 9/25/2011 | 0-1 | @ | L 31-34 | .000 | 4 | 30 | 495 | 448 | 33.3 | 100.0 | ||
| 12 | | Patriots | 9/30/2012 | 1-0 | @ | W 52-28 | 1.000 | 7 | 33 | 580 | 438 | 36.4 | |||
| 13 | | Patriots | 9/8/2013 | 1-0 | @ | W 23-21 | 1.000 | 2 | 26 | 431 | 286 | 55.0 | 0.0 | ||
| 14 | | Patriots | 10/12/2014 | 1-0 | @ | W 37-22 | 1.000 | 4 | 22 | 396 | 336 | 46.7 | |||
| 15 | | Patriots | 9/20/2015 | 1-0 | @ | W 40-32 | 1.000 | 4 | 27 | 507 | 349 | 30.0 | 0.0 | ||
| 16 | | Patriots | 10/30/2016 | 1-0 | @ | W 41-25 | 1.000 | 5 | 23 | 357 | 376 | 69.2 | |||
| 17 | | Patriots | 12/3/2017 | 1-0 | @ | W 23-3 | 1.000 | 2 | 23 | 435 | 268 | 41.7 | |||
| 18 | | Patriots | 10/29/2018 | 1-0 | @ | W 25-6 | 1.000 | 2 | 22 | 387 | 333 | 35.7 | |||
| 19 | | Patriots | 9/29/2019 | 1-0 | @ | W 16-10 | 1.000 | 2 | 11 | 224 | 375 | 27.8 | |||
| 20 | | Patriots | 11/1/2020 | 0-1 | @ | L 21-24 | .000 | 2 | 20 | 349 | 339 | 50.0 | |||
| 21 | | Patriots | 12/6/2021 | 1-0 | @ | W 14-10 | 1.000 | 1 | 11 | 241 | 230 | 16.7 | 50.0 | ||
| 22 | | Patriots | 1/15/2022 | 0-1 | @ | L 17-47 | .000 | 2 | 20 | 305 | 482 | 50.0 | 100.0 | ||
| 23 | | Patriots | 1/8/2023 | 0-1 | @ | L 23-35 | .000 | 3 | 20 | 341 | 327 | 30.8 | 100.0 | ||
| 24 | | Patriots | 12/31/2023 | 0-1 | @ | L 21-27 | .000 | 3 | 16 | 294 | 281 | 40.0 | |||
| 25 | | Patriots | 12/22/2024 | 0-1 | @ | L 21-24 | .000 | 3 | 28 | 379 | 324 | 58.3 | 100.0 | ||
| Average | .741 | 3.1 | 21.9 | 368.1 | 324.0 | 44.9 | 0.1 | ||||||||
| Total | 20-7 | .741 | 85 | 591 | 9,939 | 8,748 | 44.9 | 70.4 | |||||||
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More Patriots Stats
Team Leaders 
PASS
1,228
Maye
RUSH
227
Stevenson
REC
219
Doubs
Team Rankings
PPG
22.0
19th
OPP PPG
18.8
4th
RUSH YDS/G
127.2
10th
PASS YDS/G
254.8
11th
Jets
Dolphins
CHI
GB
DET
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 1 | .700 | |
2 | 3 | 0 | .400 | |
2 | 3 | 0 | .400 | |
1 | 3 | 1 | .300 | |
| NFC North | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
1 | 4 | 0 | .200 | |
| NFC West | W | L | T | PCT |
5 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 |
Giants
Eagles
Cowboys
Commanders
Vikings
Panthers
Falcons
Buccaneers
Saints
49ers
Seahawks
Rams
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
2 | 3 | 0 | .400 | |
0 | 5 | 0 | .000 | |
| AFC North | W | L | T | PCT |
4 | 1 | 0 | .800 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
| AFC South | W | L | T | PCT |
4 | 1 | 0 | .800 | |
2 | 3 | 0 | .400 | |
1 | 4 | 0 | .200 | |
0 | 5 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 2 | 0 | .600 | |
3 | 2 | 0 | .600 | |
0 | 5 | 0 | .000 |
Ravens
Browns
Steelers
Bengals
Jaguars
Colts
Texans
Titans
Chiefs
Broncos
Raiders
Chargers