Frank Gore has the most career rush attempts + targets per game played by a running back, with 3,737.89.
| NAME | ATT+TRG/GP | ATT | TRG | GP | RUSH YDS | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | F. Gore | 3,737.89 | 3,735 | 696 | 241 | 16,000 | 4.3 | 66.4 | 81 | 3,985 | 484 | 8.2 | 16.5 | 18 |
| 2 |  | A. Peterson | 3,232.3 | 3,230 | 423 | 184 | 14,918 | 4.6 | 81.1 | 120 | 2,474 | 305 | 8.1 | 13.4 | 6 |
| 3 |  | L. Tomlinson | 3,179.11 | 3,174 | 868 | 170 | 13,684 | 4.3 | 80.5 | 145 | 4,772 | 624 | 7.6 | 28.1 | 17 |
| 4 |  | E. James | 3,031.95 | 3,028 | 584 | 148 | 12,246 | 4.0 | 82.7 | 80 | 3,364 | 433 | 7.8 | 22.7 | 11 |
| 5 |  | S. Jackson | 2,767.92 | 2,764 | 627 | 160 | 11,438 | 4.1 | 71.5 | 69 | 3,683 | 461 | 8.0 | 23.0 | 9 |
| 6 | | T. Jones | 2,680.28 | 2,678 | 410 | 180 | 10,591 | 4.0 | 58.8 | 68 | 2,023 | 308 | 6.6 | 11.2 | 3 |
| 7 |  | D. Henry | 2,663.6 | 2,662 | 245 | 153 | 13,018 | 4.9 | 85.1 | 122 | 1,801 | 189 | 9.5 | 11.8 | 5 |
| 8 | | J. Lewis | 2,544.27 | 2,542 | 298 | 131 | 10,607 | 4.2 | 81.0 | 58 | 1,879 | 221 | 8.5 | 14.3 | 4 |
| 9 |  | L. McCoy | 2,460.91 | 2,457 | 665 | 170 | 11,102 | 4.5 | 65.3 | 73 | 3,898 | 518 | 7.5 | 22.9 | 16 |
| 10 |  | M. Lynch | 2,455.62 | 2,453 | 391 | 149 | 10,413 | 4.2 | 69.9 | 85 | 2,214 | 287 | 7.7 | 14.9 | 9 |
| 11 | | R. Williams | 2,434.17 | 2,431 | 466 | 147 | 10,009 | 4.1 | 68.1 | 66 | 2,606 | 342 | 7.6 | 17.7 | 8 |
| 12 |  | M. Forte | 2,360.96 | 2,356 | 724 | 146 | 9,796 | 4.2 | 67.1 | 54 | 4,672 | 554 | 8.4 | 32.0 | 21 |
| 13 | | F. Taylor | 2,272.52 | 2,270 | 348 | 138 | 10,472 | 4.6 | 75.9 | 52 | 1,963 | 246 | 8.0 | 14.2 | 5 |
| 14 | | C. Portis | 2,232.99 | 2,230 | 338 | 113 | 9,923 | 4.4 | 87.8 | 75 | 2,018 | 247 | 8.2 | 17.9 | 5 |
| 15 | | W. Dunn | 2,203.99 | 2,200 | 594 | 149 | 8,963 | 4.1 | 60.2 | 43 | 3,533 | 427 | 8.3 | 23.7 | 12 |
| 16 |  | C. Martin | 2,194.79 | 2,191 | 409 | 108 | 9,015 | 4.1 | 83.5 | 50 | 2,074 | 324 | 6.4 | 19.2 | 4 |
| 17 | | S. Alexander | 2,189.57 | 2,187 | 316 | 123 | 9,453 | 4.3 | 76.9 | 100 | 1,520 | 215 | 7.1 | 12.4 | 12 |
| 18 |  | C. Johnson | 2,166.26 | 2,163 | 424 | 130 | 9,651 | 4.5 | 74.2 | 55 | 2,255 | 307 | 7.3 | 17.3 | 9 |
| 19 |  | E. Elliott | 2,142.58 | 2,139 | 483 | 135 | 9,130 | 4.3 | 67.6 | 74 | 2,718 | 368 | 7.4 | 20.1 | 14 |
| 20 | | C. Dillon | 2,125.34 | 2,123 | 278 | 119 | 8,982 | 4.2 | 75.5 | 68 | 1,476 | 189 | 7.8 | 12.4 | 6 |
| 21 | | W. McGahee | 2,097.01 | 2,095 | 285 | 142 | 8,474 | 4.0 | 59.7 | 65 | 1,339 | 210 | 6.4 | 9.4 | 5 |
| 22 | | T. Barber | 2,034.61 | 2,029 | 707 | 126 | 9,772 | 4.8 | 77.6 | 52 | 4,536 | 510 | 8.9 | 36.0 | 8 |
| 23 | | A. Green | 2,024.75 | 2,021 | 495 | 132 | 8,996 | 4.5 | 68.2 | 59 | 2,881 | 375 | 7.7 | 21.8 | 14 |
| 24 | | M. Jones-Drew | 1,850.68 | 1,847 | 464 | 126 | 8,167 | 4.4 | 64.8 | 68 | 2,944 | 346 | 8.5 | 23.4 | 11 |
| 25 |  | J. Jacobs | 1,843.25 | 1,840 | 341 | 105 | 7,803 | 4.2 | 74.3 | 74 | 2,072 | 269 | 7.7 | 19.7 | 2 |
StatMuse has season-level data for targets going back to the 1999 season.
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More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |