The New Orleans Saints have a 27-51-2 record in the regular-season and playoffs against the 49ers all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Saints | 10/22/1967 | 0-1 |  NO | @ |  SF | L 13-27 | .000 | 1 | 12 | 200 | 318 | ||
| 2 | | Saints | 11/23/1969 | 1-0 | NO | vs | SF | W 43-38 | 1.000 | 5 | 26 | 402 | 433 | ||
| 3 | | Saints | 10/18/1970 | 0-0-1 | NO | @ | SF | T 20-20 | .500 | 2 | 14 | 283 | 337 | ||
| 4 | | Saints | 12/13/1970 | 0-1 | NO | vs | SF | L 27-38 | .000 | 4 | 17 | 353 | 330 | ||
| 5 | | Saints | 9/26/1971 | 0-1 | NO | vs | SF | L 20-38 | .000 | 3 | 16 | 263 | 319 | ||
| 6 | | Saints | 11/14/1971 | 1-0 | NO | @ | SF | W 26-20 | 1.000 | 3 | 17 | 338 | 333 | ||
| 7 | | Saints | 10/1/1972 | 0-1 | NO | vs | SF | L 2-37 | .000 | 0 | 8 | 84 | 318 | ||
| 8 | | Saints | 10/22/1972 | 0-0-1 | NO | @ | SF | T 20-20 | .500 | 2 | 19 | 367 | 340 | ||
| 9 | | Saints | 10/21/1973 | 0-1 | NO | @ | SF | L 0-40 | .000 | 0 | 2 | 82 | 424 | ||
| 10 | | Saints | 12/9/1973 | 1-0 | NO | vs | SF | W 16-10 | 1.000 | 1 | 14 | 274 | 268 | ||
| 11 | | Saints | 9/15/1974 | 0-1 | NO | vs | SF | L 13-17 | .000 | 1 | 22 | 278 | 214 | ||
| 12 | | Saints | 12/15/1974 | 0-1 | NO | @ | SF | L 21-35 | .000 | 3 | 23 | 318 | 338 | ||
| 13 | | Saints | 10/19/1975 | 0-1 | NO | @ | SF | L 21-35 | .000 | 3 | 18 | 241 | 267 | ||
| 14 | | Saints | 11/23/1975 | 0-1 | NO | vs | SF | L 6-16 | .000 | 0 | 18 | 280 | 228 | ||
| 15 | | Saints | 10/17/1976 | 0-1 | NO | @ | SF | L 3-33 | .000 | 0 | 9 | 95 | 309 | ||
| 16 | | Saints | 12/12/1976 | 0-1 | NO | vs | SF | L 7-27 | .000 | 1 | 11 | 299 | 360 | ||
| 17 | | Saints | 11/13/1977 | 0-1 | NO | vs | SF | L 7-10 | .000 | 1 | 12 | 194 | 287 | ||
| 18 | | Saints | 11/27/1977 | 0-1 | NO | @ | SF | L 17-20 | .000 | 2 | 13 | 183 | 343 | ||
| 19 | | Saints | 10/15/1978 | 1-0 | NO | @ | SF | W 14-7 | 1.000 | 2 | 12 | 206 | 175 | ||
| 20 | | Saints | 12/3/1978 | 1-0 | NO | vs | SF | W 24-13 | 1.000 | 3 | 24 | 383 | 287 | ||
| 21 | | Saints | 9/23/1979 | 1-0 | NO | @ | SF | W 30-21 | 1.000 | 4 | 28 | 512 | 341 | ||
| 22 | | Saints | 11/11/1979 | 1-0 | NO | vs | SF | W 31-20 | 1.000 | 4 | 27 | 368 | 393 | ||
| 23 | | Saints | 9/7/1980 | 0-1 | NO | vs | SF | L 23-26 | .000 | 3 | 19 | 394 | 350 | ||
| 24 | | Saints | 12/7/1980 | 0-1 | NO | @ | SF | L 35-38 | .000 | 5 | 27 | 519 | 430 | ||
| 25 | | Saints | 9/27/1981 | 0-1 | NO | @ | SF | L 14-21 | .000 | 2 | 18 | 413 | 314 | ||
| Average | .350 | 2.1 | 17.6 | 304.3 | 344.6 | ||||||||||
| Total | 27-51-2 | .350 | 171 | 1,406 | 24,342 | 27,567 | |||||||||
More Saints Stats
Team Rankings
PPG
15.7
29th
OPP PPG
30.0
25th
RUSH YDS/G
102.3
18th
PASS YDS/G
213.0
19th
2025 Division Standings
| TEAM | W | L | T | PCT |
|---|---|---|---|---|
 Buccaneers | 3 | 0 | 0 | 1.000 |
 Falcons | 1 | 2 | 0 | .333 |
 Panthers | 1 | 2 | 0 | .333 |
| Saints | 0 | 3 | 0 | .000 |
BUF 
NYG 
NE 
CHI 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 3 | 0 | 0 | 1.000 |
 Commanders | 2 | 1 | 0 | .667 |
| NFC North | W | L | T | PCT |
 Packers | 2 | 1 | 0 | .667 |
 Vikings | 2 | 1 | 0 | .667 |
| NFC South | W | L | T | PCT |
| Buccaneers | 3 | 0 | 0 | 1.000 |
| Panthers | 1 | 2 | 0 | .333 |
| NFC West | W | L | T | PCT |
| 49ers | 3 | 0 | 0 | 1.000 |
 Rams | 2 | 1 | 0 | .667 |
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