Since 2005-06, the St. Louis Blues have their most wins in a season in 2013-14, with 52 wins.

	TEAM	W	SEASON	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Blues	52	2013-14	82	23	7	111	.677	9	3	239	188	51	19.8	85.7	29.29	10.0	26.38	.913
2	Blues	51	2014-15	82	24	7	109	.665	9	4	239	197	42	22.3	83.7	30.91	9.4	27.23	.912
3	Blues	49	2021-22	82	22	11	109	.665	2	3	309	239	70	27.0	84.1	30.39	12.4	31.60	.908
4	Blues	49	2015-16	82	24	9	107	.652	5	4	219	197	22	21.5	85.1	30.17	8.9	29.74	.919
5	Blues	49	2011-12	82	22	11	109	.665	4	10	206	155	51	16.7	85.8	30.63	8.2	26.71	.929
6	Blues	46	2016-17	82	29	7	99	.604	2	2	233	216	17	21.3	84.8	28.41	10.0	28.38	.907
7	Blues	45	2018-19	82	28	9	99	.604	3	3	244	220	24	21.1	81.5	31.76	9.4	28.60	.906
8	Blues	44	2024-25	82	30	8	96	.585	4	2	250	231	19	22.1	74.2	26.66	11.4	27.27	.897
9	Blues	44	2017-18	82	32	6	94	.573	3	0	223	222	1	15.4	79.7	32.65	8.3	29.73	.909
10	Blues	43	2023-24	82	33	6	92	.561	5	2	234	248	-14	18.0	78.6	28.90	9.9	32.13	.906
11	Blues	42	2019-20	71	19	10	94	.662	2	3	223	190	33	24.3	79.3	30.69	10.2	29.58	.910
12	Blues	41	2008-09	82	31	10	92	.561	6	6	227	227	0	20.5	83.8	27.70	10.0	28.55	.903
13	Blues	40	2009-10	82	32	10	90	.549	7	5	218	218	0	16.9	86.8	29.82	8.9	30.16	.912
14	Blues	38	2010-11	82	33	11	87	.530	4	6	236	228	8	18.6	81.7	30.18	9.5	27.73	.900
15	Blues	37	2022-23	82	38	7	81	.494	3	3	260	298	-38	19.3	72.4	28.55	11.1	32.34	.888
16	Blues	34	2006-07	82	35	13	81	.494	6	6	208	248	-40	12.1	80.0	26.85	9.4	28.89	.895
17	Blues	33	2007-08	82	36	13	79	.482	3	5	202	232	-30	14.1	84.4	26.11	9.4	27.43	.897
18	Blues	29	2012-13	48	17	2	60	.625	5	1	124	114	10	19.5	84.7	27.83	9.3	24.19	.902
19	Blues	27	2020-21	56	20	9	63	.563	2	3	167	167	0	23.2	77.8	28.96	10.3	29.82	.900
20	Blues	21	2005-06	82	46	15	57	.348	4	8	193	284	-91	14.6	82.2	28.48	8.3	30.61	.887
21	Blues	11	2025-26	31	13	7	29	.468	0	2	79	107	-28	19.8	77.9	25.32	10.1	27.87	.876