Erik Karlsson has 4 goals, 14 assists and a plus-minus of -2 in 15 games in his last 15 games against the Sabres at home.
| NAME | DATE | TM | OPP | G | A | P | +/- | PIM | PPG | PPA | SHG | SHA | GWG | OTG | S | S% | FOW | FO | FOW% | HIT | BKS | TKA | GVA | TOI | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | E. Karlsson | 3/6/2015 |  OTT | vs |  BUF | 1 | 0 | 1 | +1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 16.7 | 0 | 0 | 2 | 4 | 0 | 1 | 28:06 | |
| 2 | | E. Karlsson | 1/26/2016 | OTT | vs | BUF | 1 | 0 | 1 | +1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 9 | 11.1 | 0 | 0 | 0 | 1 | 0 | 1 | 31:46 | |
| 3 | | E. Karlsson | 2/16/2016 | OTT | vs | BUF | 0 | 0 | 0 | -1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 8 | 0.0 | 0 | 0 | 0 | 2 | 1 | 4 | 32:02 | |
| 4 | | E. Karlsson | 11/5/2016 | OTT | vs | BUF | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 0.0 | 0 | 0 | 1 | 5 | 1 | 3 | 29:00 | |
| 5 | | E. Karlsson | 11/29/2016 | OTT | vs | BUF | 0 | 2 | 2 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 7 | 0.0 | 0 | 0 | 1 | 3 | 1 | 1 | 29:40 | |
| 6 | | E. Karlsson | 2/14/2017 | OTT | vs | BUF | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0.0 | 0 | 0 | 0 | 2 | 0 | 2 | 29:23 | |
| 7 | | E. Karlsson | 2/15/2018 | OTT | vs | BUF | 0 | 2 | 2 | +2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6 | 0.0 | 0 | 0 | 1 | 2 | 1 | 0 | 29:36 | |
| 8 | | E. Karlsson | 3/8/2018 | OTT | vs | BUF | 0 | 1 | 1 | +1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 0.0 | 0 | 0 | 0 | 2 | 1 | 2 | 29:11 | |
| 9 |  | E. Karlsson | 10/18/2018 |  SJS | vs | BUF | 0 | 1 | 1 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 20:59 | |
| 10 | | E. Karlsson | 10/19/2019 | SJS | vs | BUF | 0 | 2 | 2 | -3 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 1 | 0.0 | 0 | 0 | 1 | 2 | 0 | 2 | 28:36 | |
| 11 | | E. Karlsson | 2/18/2023 | SJS | vs |  BUF | 0 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 1 | 27:17 | ||
| 12 |  | E. Karlsson | 11/11/2023 |  PIT | vs | BUF | 2 | 0 | 2 | +1 | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 4 | 50.0 | 0 | 0 | 0 | 0 | 0 | 3 | 22:50 | |
| 13 | | E. Karlsson | 1/6/2024 | PIT | vs | BUF | 0 | 1 | 1 | -3 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 0.0 | 0 | 0 | 1 | 2 | 1 | 1 | 23:11 | |
| 14 | | E. Karlsson | 10/16/2024 | PIT | vs | BUF | 0 | 1 | 1 | -1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 0.0 | 0 | 0 | 1 | 4 | 1 | 3 | 26:37 | |
| 15 | | E. Karlsson | 11/26/2025 | PIT | vs | BUF | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 23:48 | ||
| Total | 4 | 14 | 18 | -2 | 12 | 1 | 7 | 0 | 0 | 0 | 0 | 55 | 7.3 | 0 | 0 | 9 | 31 | 9 | 24 | 412:02 |
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G/GP
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10th
GA/GP
3.22
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PP%
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11th
PK%
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