Kris Letang has the most career games by a Penguins defenseman, with 1,161 games.

Interpreted as:

most regular-season games as a penguin at defenceman

	NAME	GP	G	A	P	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Kris Letang K. Letang	1,161	175	597	772	+85	805	56	229	6	10	34	11	2,946	5.9	1	5	20.0	2,001	1,755	633	1,102	24:12
2	Brooks Orpik B. Orpik	703	13	119	132	+32	734	1	6	0	9	0	0	481	2.7	1	1	100.0	2,187	1,242	119	273	19:42
3	Ron Stackhouse R. Stackhouse	621	66	277	343	+53	547	20	90	3	4	7		1,341	4.9
4	Dave Burrows D. Burrows	573	24	108	132	-55	301	4	13	1	4	5		823	2.9
5	Brian Dumoulin B. Dumoulin	546	19	120	139	+93	146	0	5	1	7	1	0	645	2.9	1	1	100.0	762	816	239	291	20:39
6	Rob Scuderi R. Scuderi	460	4	53	57	+18	139	0	0	0	3	0	0	231	1.7	0	1	0.0	250	734	121	211	19:03
7	Marcus Pettersson M. Pettersson	442	16	125	141	+68	271	1	6	0	2	2	1	525	3.0	1	1	100.0	675	646	140	232	19:22
8	Rod Buskas R. Buskas	431	16	48	64	-56	959	4	6	0	0	1	0	328	4.9
9	Darius Kasparaitis D. Kasparaitis	405	15	68	83	+37	661	2	4	2	4	1	0	381	3.9	0	1	0.0	928	379	46	148	19:16
10	Randy Carlyle R. Carlyle	397	66	257	323	-100	582	28	137	4	4	6	1	1,049	6.3
11	Jim Johnson J. Johnson	390	14	95	109	-16	658	2	19	0	2	1	0	414	3.4
12	Olli Maatta O. Maatta	362	25	82	107	+61	98	4	17	1	1	7	0	545	4.6	0	0		440	565	65	202	18:54
13	Russ Anderson R. Anderson	353	15	77	92	+18	684	1	3	0	0	3		268	5.6
14	Randy Hillier R. Hillier	343	13	79	92	-7	594	1	4	1	6	2	2	271	4.8
15	Larry Murphy L. Murphy	336	78	223	301	+102	213	26	104	4	4	12	1	881	8.9
16	Ian Moran I. Moran	334	14	33	47	-45	225	0	2	0	1	2	0	404	3.5	77	220	35.0	185	210	33	61	16:41
17	Paul Coffey P. Coffey	331	108	332	440	-50	573	40	185	2	5	11	0	1,306	8.3
18	Chad Ruhwedel C. Ruhwedel	326	13	34	47	-7	90	0	3	0	0	1	0	346	3.8	0	0		563	297	80	87	15:02
19	Sergei Gonchar S. Gonchar	322	54	205	259	-3	313	37	138	1	5	11	3	765	7.1	0	0		268	482	107	197	25:26
20	Josef Melichar J. Melichar	310	7	33	40	-26	263	0	3	1	3	0	0	249	2.8	0	0		336	405	74	126	17:50
21	Bryan Watson B. Watson	303	8	57	65	-5	871	1	2	0	1	1		323	2.5
22	Doug Bodger D. Bodger	299	35	132	167	-12	292	22	64	0	4	4	1	641	5.5
23	Paul Martin P. Martin	297	17	92	109	+45	80	5	28	0	2	4	0	350	4.9	0	0		176	509	113	130	23:31
24	Ulf Samuelsson U. Samuelsson	277	11	83	94	+76	804	2	19	0	6	2	1	339	3.2
25	Duane Rupp D. Rupp	265	21	83	104	-35	170	4	34	1	1	3		549	3.8