Since 2020-21, the Colorado Avalanche have the most wins by a team, with 261 wins.

Interpreted as:

most regular-season wins in NHL since 2021

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Avalanche	261	406	111	34	556	.685	16	13	1,442	1,118	324	23.6	80.5	33.06	10.7	28.89	.905
2	Hurricanes	255	406	112	39	549	.676	12	16	1,334	1,049	285	22.0	85.2	33.29	9.9	26.44	.902
3	Panthers	248	406	128	30	526	.648	16	10	1,393	1,153	240	22.9	79.6	34.53	9.9	29.06	.902
4	Maple Leafs	246	406	118	42	534	.658	11	7	1,415	1,192	223	24.3	79.6	31.51	11.1	29.61	.901
5	Bruins	242	408	124	42	526	.645	15	11	1,277	1,095	182	20.9	82.7	31.29	10.0	29.13	.908
6	Oilers	241	409	135	33	515	.630	7	9	1,421	1,225	196	27.4	79.0	32.56	10.7	29.63	.899
7	Golden Knights	239	406	123	44	522	.643	15	18	1,324	1,112	212	21.1	79.1	31.86	10.2	28.83	.905
8	Lightning	238	406	133	35	511	.629	11	13	1,394	1,168	226	24.9	82.0	29.97	11.5	29.44	.902
9	Jets	235	405	143	27	497	.614	6	9	1,266	1,076	190	22.0	79.1	30.04	10.4	30.09	.912
10	Stars	232	407	122	53	517	.635	19	17	1,317	1,124	193	24.0	81.0	30.26	10.7	29.20	.905
11	Rangers	231	408	139	38	500	.613	15	11	1,292	1,119	173	22.9	82.0	29.75	10.6	29.76	.908
12	Wild	230	407	133	44	504	.619	21	17	1,263	1,187	76	21.2	77.0	29.88	10.4	30.42	.904
13	Capitals	218	407	140	49	485	.596	16	19	1,289	1,206	83	21.1	80.7	29.23	10.8	29.16	.898
14	Kings	215	407	138	54	484	.595	15	20	1,215	1,128	87	20.1	80.2	31.19	9.6	27.92	.901
15	Blues	207	407	153	47	461	.566	16	15	1,281	1,266	15	21.8	77.4	28.50	11.0	30.52	.898
16	Penguins	205	405	146	54	464	.573	10	21	1,282	1,230	52	21.4	80.3	31.93	9.9	30.83	.902
17	Flames	201	408	154	53	455	.558	12	16	1,234	1,187	47	19.6	80.7	32.45	9.3	28.65	.898
18	Predators	201	406	171	34	436	.537	21	4	1,165	1,243	-78	20.6	79.6	30.04	9.6	30.98	.901
19	Canucks	198	407	161	48	444	.545	17	12	1,245	1,272	-27	22.2	77.0	28.81	10.6	30.09	.896
20	Islanders	198	407	153	56	452	.555	11	24	1,160	1,152	8	17.6	78.9	29.64	9.6	30.69	.908
21	Devils	192	406	177	37	421	.518	9	18	1,250	1,281	-31	21.0	80.2	30.70	10.0	29.15	.892
22	Senators	188	406	183	35	411	.506	15	6	1,199	1,307	-108	20.6	78.1	30.69	9.6	30.63	.895
23	Red Wings	179	407	180	48	406	.499	16	10	1,166	1,359	-193	20.6	76.5	28.43	10.1	31.07	.893
24	Sabres	173	406	191	42	388	.478	17	12	1,235	1,385	-150	20.1	77.3	29.88	10.2	31.43	.891
25	Flyers	163	405	186	56	382	.472	20	15	1,109	1,367	-258	14.7	77.6	29.85	9.2	29.57	.886