Since 1999-00, the Boston Bruins have the most wins by a team, with 1,065 wins.

Interpreted as:

NHL most regular-season wins since 2000

	TEAM	W	GP	L	T	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Bruins	1,065	1,998	648	59	226	2,415	.604	79	91	5,824	5,239	585	18.8	83.0	31.32	9.3	29.36	.911
2	Stars	1,058	1,996	679	59	200	2,375	.595	90	72	5,715	5,300	415	18.9	82.3	29.28	9.8	28.45	.907
3	Capitals	1,050	1,995	687	51	207	2,358	.591	81	88	5,965	5,619	346	20.2	81.5	29.41	10.2	30.03	.906
4	Avalanche	1,046	1,996	723	55	172	2,319	.581	89	54	5,942	5,543	399	19.5	81.5	30.12	9.9	29.84	.907
5	Blues	1,037	1,998	705	53	203	2,330	.583	88	81	5,675	5,360	315	18.7	82.8	29.16	9.7	27.86	.904
6	Red Wings	1,031	1,997	695	50	221	2,333	.584	85	83	5,827	5,591	236	20.1	81.9	30.81	9.5	28.95	.903
7	Penguins	1,028	1,995	727	39	201	2,296	.575	90	74	6,035	5,802	233	19.7	81.9	30.47	9.9	30.40	.904
8	Rangers	1,012	1,997	762	38	185	2,247	.563	93	77	5,701	5,459	242	18.3	82.1	30.16	9.5	30.06	.909
9	Lightning	1,007	1,995	756	50	182	2,246	.563	78	70	5,971	5,816	155	19.4	81.6	29.37	10.2	29.67	.902
10	Maple Leafs	1,006	1,997	738	45	208	2,265	.567	69	84	6,051	5,876	175	19.4	80.5	30.12	10.1	30.33	.903
11	Canucks	995	1,996	742	56	203	2,249	.563	86	87	5,709	5,549	160	18.9	81.9	29.26	9.8	29.56	.906
12	Devils	995	1,995	750	51	199	2,240	.561	87	97	5,392	5,301	91	18.4	83.1	29.60	9.1	27.94	.905
13	Predators	994	1,996	754	53	195	2,236	.560	90	74	5,477	5,451	26	17.3	82.2	29.33	9.4	29.94	.909
14	Sharks	979	1,997	751	51	216	2,225	.557	83	87	5,615	5,584	31	19.2	82.4	30.14	9.3	29.12	.904
15	Hurricanes	977	1,994	753	60	204	2,218	.556	58	74	5,602	5,562	40	17.5	82.8	31.21	9.0	28.51	.902
16	Senators	974	1,998	778	47	199	2,194	.549	71	84	5,860	5,743	117	18.7	81.8	30.65	9.6	30.12	.905
17	Kings	964	1,997	765	58	210	2,196	.550	83	89	5,431	5,358	73	18.0	81.5	30.00	9.1	27.97	.904
18	Flyers	962	1,995	741	61	231	2,216	.555	70	103	5,697	5,698	-1	18.2	81.7	30.43	9.4	29.07	.902
19	Flames	956	1,998	785	57	200	2,169	.543	62	80	5,530	5,590	-60	17.5	81.5	29.72	9.3	28.79	.903
20	Wild	950	1,914	716	55	193	2,148	.561	90	86	5,164	5,088	76	17.9	82.3	28.16	9.6	29.65	.910
21	Ducks	936	1,997	789	50	222	2,144	.537	84	90	5,289	5,611	-322	17.9	81.4	28.87	9.2	30.52	.908
22	Jets	928	1,997	847	45	177	2,078	.520	79	66	5,689	6,021	-332	17.8	79.9	29.17	9.8	31.28	.904
23	Canadiens	927	1,997	805	44	221	2,119	.531	83	83	5,439	5,694	-255	18.1	81.6	29.06	9.4	30.78	.907
24	Oilers	915	1,999	824	63	197	2,090	.523	82	78	5,663	5,873	-210	18.9	81.2	29.16	9.7	29.90	.902
25	Panthers	914	1,995	791	57	233	2,118	.531	86	105	5,543	5,734	-191	17.8	81.4	30.97	9.0	31.44	.909