Since 2020-21, the Colorado Avalanche have the most wins by a team, with 251 wins.

Interpreted as:

NHL most regular-season wins since 2021

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Avalanche	251	395	111	33	535	.677	16	13	1,395	1,098	297	23.9	80.4	33.10	10.7	28.96	.904
2	Hurricanes	248	394	109	37	533	.676	12	15	1,296	1,015	281	22.0	85.5	33.26	9.9	26.53	.903
3	Maple Leafs	242	395	113	40	524	.663	11	7	1,379	1,152	227	24.4	79.6	31.67	11.0	29.50	.901
4	Panthers	241	395	124	30	512	.648	15	10	1,351	1,116	235	23.0	79.6	34.70	9.9	29.08	.903
5	Oilers	236	396	129	31	503	.635	7	8	1,382	1,170	212	27.5	79.1	32.72	10.7	29.67	.900
6	Bruins	235	397	120	42	512	.645	14	11	1,246	1,065	181	20.6	82.6	31.36	10.0	29.11	.908
7	Golden Knights	235	394	119	40	510	.647	15	18	1,293	1,075	218	21.1	79.0	31.88	10.3	28.94	.906
8	Jets	231	395	137	27	489	.619	5	9	1,240	1,045	195	22.1	79.3	30.09	10.4	30.17	.912
9	Lightning	230	395	130	35	495	.627	11	13	1,356	1,139	217	25.0	81.9	30.09	11.4	29.52	.902
10	Rangers	225	396	133	38	488	.616	14	11	1,260	1,085	175	22.8	82.2	29.93	10.6	29.77	.908
11	Stars	224	395	120	51	499	.632	18	15	1,268	1,093	175	23.6	81.0	30.39	10.6	29.27	.905
12	Wild	221	396	132	43	485	.612	20	17	1,228	1,170	58	21.2	76.7	30.01	10.3	30.46	.903
13	Capitals	212	394	135	47	471	.598	16	17	1,240	1,167	73	21.4	81.0	29.19	10.8	29.26	.899
14	Kings	209	396	135	52	470	.593	15	19	1,189	1,105	84	20.4	79.9	31.24	9.6	28.04	.900
15	Penguins	203	396	142	51	457	.577	10	20	1,262	1,204	58	21.2	80.0	32.01	10.0	30.96	.902
16	Blues	203	395	149	43	449	.568	16	14	1,252	1,230	22	21.9	77.3	28.62	11.1	30.52	.898
17	Predators	199	396	165	32	430	.543	21	4	1,142	1,203	-61	20.6	79.7	30.08	9.6	31.13	.902
18	Canucks	195	396	155	46	436	.551	17	12	1,207	1,222	-15	22.0	77.2	28.81	10.6	30.08	.897
19	Flames	195	396	149	52	442	.558	11	15	1,203	1,158	45	19.8	80.6	32.49	9.3	28.72	.898
20	Islanders	189	394	150	55	433	.549	10	23	1,124	1,126	-2	17.8	78.3	29.71	9.6	30.82	.907
21	Devils	186	395	173	36	408	.516	7	18	1,224	1,249	-25	21.2	80.2	30.72	10.1	29.15	.892
22	Senators	183	396	181	32	398	.503	15	6	1,173	1,283	-110	20.8	78.0	30.90	9.6	30.80	.895
23	Red Wings	174	395	174	47	395	.500	15	10	1,137	1,319	-182	20.8	76.6	28.30	10.2	31.23	.893
24	Sabres	168	395	186	41	377	.477	16	12	1,198	1,345	-147	20.3	77.1	30.03	10.1	31.45	.892
25	Flyers	158	394	182	54	370	.470	18	15	1,081	1,332	-251	14.7	77.6	29.94	9.2	29.73	.886