Between the 2009-10 and 2018-19 seasons, the Pittsburgh Penguins had the most wins by a team, with 466 wins.

Interpreted as:

NHL team most regular-season wins 2010s

	TEAM	W	GP	L	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Penguins	466	786	243	77	1,009	.642	53	31	2,431	2,090	341	20.8	83.4	32.51	9.5	29.90	.911
2	Capitals	462	786	233	91	1,015	.646	45	40	2,397	2,056	341	22.2	81.7	30.04	10.2	30.36	.914
3	Blues	443	786	264	79	965	.614	51	38	2,181	1,955	226	19.2	84.1	30.27	9.2	28.04	.911
4	Bruins	442	786	250	94	978	.622	43	48	2,286	1,917	369	19.9	83.6	32.30	9.0	29.61	.918
5	Sharks	441	786	258	87	969	.616	54	43	2,290	2,044	246	20.8	81.7	32.48	9.0	28.90	.910
6	Blackhawks	437	786	255	94	968	.616	52	40	2,354	2,113	241	18.7	80.2	32.41	9.2	29.73	.910
7	Lightning	436	786	274	76	948	.603	44	39	2,387	2,204	183	20.2	81.5	29.96	10.1	30.20	.907
8	Ducks	426	786	264	96	948	.603	42	48	2,156	2,081	75	19.1	82.2	29.42	9.3	30.46	.913
9	Predators	422	786	265	99	943	.600	45	49	2,170	2,033	137	17.9	81.1	30.22	9.1	29.62	.913
10	Rangers	417	786	291	78	912	.580	43	40	2,188	2,037	151	18.1	82.3	30.16	9.2	30.48	.915
11	Kings	408	786	289	89	905	.576	47	49	2,033	1,910	123	18.2	82.8	30.41	8.5	27.79	.913
12	Canadiens	397	786	296	93	887	.564	44	41	2,091	2,072	19	18.0	82.6	30.36	8.8	30.46	.913
13	Wild	396	786	301	89	881	.560	45	45	2,063	2,077	-14	18.4	81.8	28.77	9.1	29.58	.911
14	Stars	393	786	303	90	876	.557	37	39	2,199	2,219	-20	18.2	80.3	30.19	9.3	30.37	.907
15	Flyers	392	786	290	104	888	.565	33	59	2,238	2,209	29	19.8	81.1	31.13	9.1	29.86	.906
16	Canucks	391	786	305	90	872	.555	47	48	2,117	2,127	-10	18.7	82.4	29.96	9.0	30.65	.912
17	Flames	384	786	318	84	852	.542	34	46	2,164	2,200	-36	18.0	81.1	29.33	9.4	29.23	.904
18	Jets	384	786	311	91	859	.546	42	39	2,238	2,280	-42	18.2	80.2	30.38	9.4	31.03	.907
19	Red Wings	381	786	291	114	876	.557	49	51	2,132	2,175	-43	18.8	81.1	30.68	8.8	29.90	.907
20	Blue Jackets	380	786	325	81	841	.535	46	42	2,142	2,231	-89	17.3	80.7	30.10	9.1	30.82	.908
21	Islanders	372	786	315	99	843	.536	54	48	2,181	2,321	-140	17.8	79.6	30.44	9.1	31.05	.905
22	Avalanche	363	786	342	81	807	.513	48	23	2,115	2,318	-203	18.2	80.3	29.45	9.1	32.02	.908
23	Devils	361	786	324	101	823	.524	41	55	1,910	2,078	-168	18.2	83.3	27.98	8.7	28.51	.907
24	Senators	361	786	330	95	817	.520	44	50	2,123	2,316	-193	17.4	81.2	30.46	8.9	32.20	.908
25	Maple Leafs	360	786	329	97	817	.520	41	47	2,221	2,357	-136	18.5	79.7	30.30	9.3	32.34	.907