Between the 1979-80 and 1988-89 seasons, the Philadelphia Flyers and the Edmonton Oilers were tied for the most wins, with 446 wins.

NHL teams with most regular-season wins in the 1980s

	TEAM	W	GP	L	T	PTS	PTS%	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Flyers	446	800	254	100	992	.620	3,233	2,650	583	22.0	79.9	33.10	12.2	29.23	.887
2	Oilers	446	800	250	104	996	.623	3,803	3,059	744	23.8	79.6	30.98	15.3	31.46	.878
3	Canadiens	435	800	252	113	983	.614	3,185	2,515	670	22.4	80.7	30.92	12.9	27.06	.884
4	Bruins	418	800	281	101	937	.586	3,116	2,638	478	21.7	80.7	30.26	12.9	26.37	.875
5	Islanders	414	800	288	98	926	.579	3,204	2,721	483	24.6	79.1	30.06	13.3	30.95	.890
6	Flames	398	800	288	114	910	.569	3,363	2,980	383	25.2	79.2	31.44	13.4	31.14	.880
7	Sabres	389	800	293	118	896	.560	3,025	2,706	319	21.3	80.2	29.65	12.8	27.89	.879
8	Capitals	379	800	311	110	868	.543	2,988	2,755	233	20.9	79.5	30.41	12.3	28.60	.880
9	Rangers	353	800	348	99	805	.503	3,048	3,032	16	21.7	78.8	30.78	12.4	30.55	.876
10	Blues	341	800	344	115	797	.498	2,946	2,991	-45	21.6	78.8	29.94	12.3	30.58	.878
11	Nordiques	338	800	358	104	780	.488	3,081	3,078	3	22.4	78.2	29.32	13.1	30.14	.872
12	Blackhawks	335	800	350	115	785	.491	3,023	3,128	-105	22.7	77.2	31.34	12.1	32.99	.881
13	North Stars	326	800	335	139	791	.494	3,005	3,005	0	22.8	78.6	31.68	11.9	31.98	.883
14	Kings	307	800	381	112	726	.454	3,193	3,463	-270	22.5	74.6	30.86	12.9	31.42	.862
15	Whalers	301	800	395	104	706	.441	2,843	3,205	-362	20.8	78.5	29.53	12.0	30.94	.871
16	Jets	294	800	400	106	694	.434	2,954	3,393	-439	21.3	77.0	30.91	11.9	31.46	.865
17	Penguins	289	800	416	95	673	.421	2,926	3,414	-488	22.0	75.6	30.22	12.1	32.51	.869
18	Canucks	282	800	394	124	688	.430	2,815	3,126	-311	21.0	77.3	30.19	11.7	30.05	.870
19	Red Wings	271	800	415	114	656	.410	2,825	3,294	-469	19.9	76.5	29.38	12.0	29.92	.862
20	Maple Leafs	263	800	443	94	620	.388	2,902	3,541	-639	20.2	75.8	30.13	12.0	33.70	.869
21	Devils	237	800	466	97	571	.357	2,627	3,411	-784	19.0	75.6	28.69	11.4	30.85	.862