Nicolas Deslauriers has played 12 seasons for 5 teams, including the Sabres and Flyers. He has 53 goals and 51 assists in 677 games.
| NAME | SEASON | TM | GP | G | A | P | +/- | PIM | PPG | PPA | SHG | SHA | GWG | OTG | S | S% | FOW | FO | FOW% | HIT | BKS | TKA | GVA | TOI/GP | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | N. Deslauriers | 2013-14 |  BUF | 17 | 1 | 0 | 1 | -10 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 30 | 3.3 | 0 | 1 | 0.0 | 51 | 3 | 2 | 1 | 13:09 |
| 2 | | N. Deslauriers | 2014-15 | BUF | 82 | 5 | 10 | 15 | -24 | 71 | 0 | 0 | 0 | 1 | 1 | 0 | 76 | 6.6 | 0 | 1 | 0.0 | 261 | 36 | 9 | 8 | 11:52 |
| 3 | | N. Deslauriers | 2015-16 | BUF | 70 | 6 | 6 | 12 | -14 | 59 | 0 | 0 | 0 | 0 | 1 | 0 | 72 | 8.3 | 0 | 1 | 0.0 | 206 | 30 | 14 | 8 | 10:20 |
| 4 | | N. Deslauriers | 2016-17 | BUF | 42 | 0 | 2 | 2 | -6 | 38 | 0 | 0 | 0 | 0 | 0 | 0 | 26 | 0.0 | 0 | 3 | 0.0 | 109 | 5 | 2 | 3 | 7:25 |
| 5 | | N. Deslauriers | 2017-18 |  MTL | 58 | 10 | 4 | 14 | +7 | 55 | 0 | 0 | 0 | 1 | 1 | 0 | 77 | 13.0 | 4 | 6 | 66.7 | 238 | 30 | 14 | 3 | 11:36 |
| 6 | | N. Deslauriers | 2018-19 | MTL | 48 | 2 | 3 | 5 | -12 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 48 | 4.2 | 1 | 1 | 100.0 | 135 | 22 | 11 | 9 | 10:02 |
| 7 | | N. Deslauriers | 2019-20 |  ANA | 59 | 7 | 6 | 13 | -1 | 92 | 0 | 0 | 0 | 0 | 1 | 0 | 64 | 10.9 | 0 | 0 | 137 | 32 | 10 | 10 | 9:47 | |
| 8 | | N. Deslauriers | 2020-21 | ANA | 49 | 5 | 5 | 10 | -7 | 53 | 0 | 0 | 0 | 0 | 2 | 0 | 65 | 7.7 | 1 | 4 | 25.0 | 136 | 20 | 4 | 5 | 11:19 |
| 9 | | N. Deslauriers | 2021-22 | TOT | 81 | 8 | 5 | 13 | -11 | 113 | 0 | 0 | 1 | 0 | 1 | 0 | 90 | 8.9 | 1 | 4 | 25.0 | 263 | 49 | 7 | 14 | 11:22 |
| 10 | | N. Deslauriers | 2022-23 |  PHI | 80 | 6 | 6 | 12 | -11 | 136 | 0 | 0 | 1 | 0 | 0 | 0 | 70 | 8.6 | 3 | 11 | 27.3 | 306 | 26 | 13 | 8 | 10:06 |
| 11 | | N. Deslauriers | 2023-24 | PHI | 60 | 1 | 3 | 4 | -7 | 89 | 0 | 0 | 0 | 0 | 0 | 0 | 49 | 2.0 | 5 | 13 | 38.5 | 188 | 21 | 14 | 5 | 8:09 |
| 12 | | N. Deslauriers | 2024-25 | PHI | 31 | 2 | 1 | 3 | -9 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 25 | 8.0 | 1 | 3 | 33.3 | 85 | 9 | 1 | 9 | 7:38 |
| Total | 677 | 53 | 51 | 104 | -105 | 761 | 0 | 0 | 3 | 2 | 7 | 0 | 692 | 7.7 | 16 | 48 | 33.3 | 2,115 | 283 | 101 | 83 | 10:18 |
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 Penguins | 1 | 0 | 0 | 2 | 3 |
 Hurricanes | 0 | 0 | 0 | 0 | 0 |
 Blue Jackets | 0 | 0 | 0 | 0 | 0 |
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