The Ottawa Senators have 161 games played against the Sabres all-time.

ottawa senators las 5 or more regular-season games vs buffalo

	TEAM	DATE	GP	TM		OPP	RESULT	G	GA	PPG	PPO	OPP PPG	OPP PPO	S	SA
1	Senators	10/30/1992	1	OTT	@	BUF	L 3-12	3	12	2	7	4	7	20	46
2	Senators	10/31/1992	1	OTT	vs	BUF	T 2-2	2	2	1	9	1	8	37	30
3	Senators	11/27/1992	1	OTT	@	BUF	L 1-4	1	4	1	6	1	7	32	28
4	Senators	11/29/1992	1	OTT	vs	BUF	L 2-5	2	5	0	7	2	8	22	24
5	Senators	1/2/1993	1	OTT	vs	BUF	L 2-7	2	7	1	9	2	8	32	39
6	Senators	2/8/1993	1	OTT	vs	BUF	W 4-2	4	2	2	6	0	3	35	35
7	Senators	3/28/1993	1	OTT	@	BUF	L 1-3	1	3	1	7	1	8	28	34
8	Senators	11/22/1993	1	OTT	vs	BUF	L 2-5	2	5	1	10	2	3	35	25
9	Senators	11/26/1993	1	OTT	@	BUF	L 2-5	2	5	2	4	2	4	22	39
10	Senators	12/8/1993	1	OTT	vs	BUF	L 1-3	1	3	0	4	0	3	21	28
11	Senators	3/2/1994	1	OTT	vs	BUF	L 2-7	2	7	1	5	2	6	27	34
12	Senators	3/20/1994	1	OTT	@	BUF	L 2-6	2	6	0	5	5	14	15	35
13	Senators	1/28/1995	1	OTT	vs	BUF	T 2-2	2	2	0	5	2	6	26	32
14	Senators	3/18/1995	1	OTT	vs	BUF	W 4-3	4	3	1	7	1	7	31	27
15	Senators	3/30/1995	1	OTT	@	BUF	L 0-7	0	7	0	2	3	5	35	32
16	Senators	4/16/1995	1	OTT	@	BUF	L 1-2	1	2	0	4	1	4	25	34
17	Senators	10/7/1995	1	OTT	vs	BUF	L 1-3	1	3	0	5	1	3	39	19
18	Senators	11/19/1995	1	OTT	@	BUF	L 0-6	0	6	0	7	3	5	31	41
19	Senators	12/23/1995	1	OTT	vs	BUF	L 2-4	2	4	0	6	1	7	17	36
20	Senators	12/27/1995	1	OTT	@	BUF	W 4-3	4	3	1	4	0	1	34	29
21	Senators	2/28/1996	1	OTT	vs	BUF	L 2-3	2	3	1	6	2	6	37	31
22	Senators	4/10/1996	1	OTT	@	BUF	L 2-5	2	5	1	8	1	3	34	35
23	Senators	11/29/1996	1	OTT	@	BUF	L 0-3	0	3	0	3	1	5	31	25
24	Senators	12/21/1996	1	OTT	vs	BUF	L 2-3	2	3	1	3	0	2	29	25
25	Senators	2/9/1997	1	OTT	@	BUF	L 1-2	1	2	1	6	0	1	33	20
	Total		161					424	450	109	688	117	662	5,181	4,796