Since 2021-22, Tage Thompson has recorded the most points for the Sabres, with 299 points.

	NAME	P	GP	G	A	+/-	PIM	PPG	PPA	SHG	SHA	GWG	OTG	S	S%	FOW	FO	FOW%	HIT	BKS	TKA	GVA	TOI/GP
1	Tage Thompson T. Thompson	299	314	162	137	-21	164	47	39	5	0	20	2	1,086	14.9	1,446	3,411	42.4	288	118	149	167	18:22
2	Rasmus Dahlin R. Dahlin	262	323	66	196	-10	290	21	78	0	2	8	3	842	7.8	0	0		532	488	158	287	24:52
3	Alex Tuch A. Tuch	254	292	110	144	+40	160	15	35	10	3	20	2	773	14.2	163	399	40.9	233	303	238	177	19:08
4	Jeff Skinner J. Skinner	191	233	92	99	-1	105	21	23	0	0	10	2	715	12.9	285	648	44.0	76	47	129	131	16:51
5	Dylan Cozens D. Cozens	184	300	73	111	-39	200	11	30	5	2	4	2	710	10.3	1,925	4,056	47.5	346	116	110	142	16:41
6	JJ Peterka	150	238	67	83	-6	88	11	19	0	0	9	0	527	12.7	10	36	27.8	76	46	85	133	16:05
7	Casey Mittelstadt C. Mittelstadt	125	184	35	90	-10	54	7	24	1	0	4	2	316	11.1	966	2,092	46.2	63	51	96	93	16:40
8	Owen Power O. Power	115	252	20	95	+3	72	1	19	0	4	2	1	404	5.0	0	0		106	328	80	173	22:37
9	Victor Olofsson V. Olofsson	104	198	55	49	-40	14	15	12	0	1	12	2	391	14.1	1	9	11.1	48	40	58	48	14:01
10	Jack Quinn J. Quinn	103	189	42	61	-30	41	8	17	0	1	8	0	329	12.8	15	49	30.6	117	59	51	99	14:35
11	Peyton Krebs P. Krebs	96	294	30	66	-28	210	2	12	2	0	4	0	290	10.3	951	2,071	45.9	382	85	59	123	13:37
12	Kyle Okposo K. Okposo	95	210	44	51	-21	109	11	11	4	0	4	0	430	10.2	385	806	47.8	198	78	71	67	15:06
13	Zach Benson Z. Benson	66	154	21	45	-2	102	3	6	0	1	1	0	234	9.0	11	41	26.8	74	70	55	68	14:54
14	Ryan McLeod R. McLeod	60	90	23	37	+13	16	0	3	4	3	2	0	108	21.3	701	1,388	50.5	19	41	28	80	16:57
15	Jason Zucker J. Zucker	59	84	25	34	-4	61	13	12	0	0	5	0	169	14.8	52	135	38.5	83	23	22	82	15:49
16	Henri Jokiharju H. Jokiharju	58	236	12	46	0	86	0	4	0	1	3	1	290	4.1	0	0		263	255	58	139	19:46
17	Bowen Byram B. Byram	52	111	11	41	+10	65	0	5	0	1	2	0	128	8.6	0	0		119	163	23	102	22:32
18	Zemgus Girgensons Z. Girgensons	50	199	28	22	-13	62	3	2	0	0	4	0	279	10.0	331	691	47.9	319	110	55	23	13:08
19	Mattias Samuelsson M. Samuelsson	47	209	9	38	+14	88	0	1	0	1	3	0	225	4.0	0	0		431	354	48	132	20:30
20	Jordan Greenway J. Greenway	40	119	17	23	+3	111	1	2	0	1	1	0	177	9.6	26	101	25.7	272	107	39	47	16:09
21	Vincent Hinostroza V. Hinostroza	36	88	15	21	-12	30	1	0	0	1	3	0	130	11.5	13	32	40.6	26	20	30	33	13:30
22	Rasmus Asplund R. Asplund	35	107	10	25	-5	10	2	2	2	0	1	1	163	6.1	48	116	41.4	40	22	25	23	13:32
23	Jacob Bryson J. Bryson	35	221	3	32	-36	40	1	6	0	1	0	0	106	2.8	0	0		122	237	49	75	15:41
24	Connor Clifton C. Clifton	34	152	5	29	+6	113	0	0	0	3	1	0	140	3.6	0	0		410	233	53	91	16:19
25	Jiri Kulich J. Kulich	29	74	18	11	-9	22	0	0	0	0	3	1	154	11.7	320	720	44.4	49	48	16	42	15:06