Since 1999-00, the Boston Bruins have the most wins by a team, with 1,072 wins.

Interpreted as:

team with most regular-season wins since 2000

	TEAM	W	GP	L	T	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Bruins	1,072	2,010	653	59	226	2,429	.604	80	91	5,862	5,272	590	18.9	83.0	31.30	9.3	29.38	.911
2	Stars	1,067	2,010	682	59	202	2,395	.596	91	73	5,761	5,334	427	19.0	82.3	29.24	9.8	28.44	.907
3	Capitals	1,060	2,009	689	51	209	2,380	.592	81	90	6,020	5,652	368	20.2	81.5	29.40	10.2	30.03	.906
4	Avalanche	1,057	2,010	724	55	174	2,343	.583	89	56	5,996	5,569	427	19.5	81.5	30.16	9.9	29.83	.907
5	Blues	1,043	2,012	710	53	206	2,345	.583	88	81	5,706	5,403	303	18.7	82.8	29.13	9.7	27.87	.904
6	Red Wings	1,039	2,012	700	50	223	2,351	.584	85	85	5,875	5,639	236	20.1	81.8	30.81	9.5	28.95	.903
7	Penguins	1,033	2,007	730	39	205	2,310	.575	90	76	6,072	5,841	231	19.8	81.9	30.47	9.9	30.38	.904
8	Rangers	1,018	2,011	768	38	187	2,261	.562	93	77	5,739	5,500	239	18.3	82.1	30.12	9.5	30.06	.909
9	Lightning	1,016	2,010	761	50	183	2,265	.563	78	71	6,023	5,849	174	19.4	81.6	29.38	10.2	29.64	.902
10	Maple Leafs	1,012	2,009	741	45	211	2,280	.567	69	85	6,086	5,905	181	19.4	80.6	30.10	10.1	30.34	.903
11	Devils	1,000	2,009	759	51	199	2,250	.560	87	97	5,427	5,350	77	18.4	83.0	29.60	9.1	27.96	.905
12	Predators	1,000	2,008	760	53	195	2,248	.560	91	74	5,514	5,494	20	17.3	82.2	29.33	9.4	29.95	.909
13	Canucks	998	2,008	750	56	204	2,256	.562	86	87	5,740	5,593	147	18.9	81.9	29.24	9.8	29.54	.906
14	Sharks	987	2,011	757	51	216	2,241	.557	84	87	5,654	5,631	23	19.2	82.4	30.10	9.3	29.14	.904
15	Hurricanes	985	2,007	757	60	205	2,235	.557	60	75	5,638	5,596	42	17.5	82.8	31.21	9.0	28.47	.902
16	Senators	979	2,010	785	47	199	2,204	.548	72	84	5,893	5,780	113	18.7	81.8	30.64	9.6	30.10	.904
17	Flyers	969	2,007	744	61	233	2,232	.556	71	104	5,735	5,731	4	18.2	81.6	30.39	9.4	29.06	.902
18	Kings	968	2,009	768	58	215	2,209	.550	83	91	5,459	5,383	76	17.9	81.5	29.99	9.1	27.97	.904
19	Flames	964	2,011	789	57	201	2,186	.544	63	80	5,570	5,625	-55	17.5	81.6	29.72	9.3	28.78	.903
20	Wild	960	1,927	718	55	194	2,169	.563	92	87	5,202	5,113	89	17.9	82.3	28.15	9.6	29.66	.911
21	Ducks	944	2,011	795	50	222	2,160	.537	87	90	5,333	5,660	-327	17.9	81.4	28.89	9.2	30.50	.908
22	Canadiens	933	2,010	810	44	223	2,133	.531	85	84	5,478	5,743	-265	18.1	81.6	29.04	9.4	30.77	.907
23	Jets	932	2,010	855	45	178	2,087	.519	79	67	5,726	6,066	-340	17.8	79.9	29.16	9.8	31.25	.903
24	Oilers	921	2,011	828	63	199	2,104	.523	82	78	5,710	5,913	-203	18.9	81.2	29.16	9.7	29.89	.902
25	Panthers	921	2,008	796	57	234	2,133	.531	86	105	5,591	5,779	-188	17.8	81.4	30.97	9.0	31.42	.908