Since 2002-03, Marc-Andre Fleury has lost the most games by a goalie, with 339 losses.

Interpreted as:

most regular-season losses as a goalie since 2002-03

	NAME	L	GP	GS	W	T	OTL	SA	SV	SV%	GA	GAA	SHO	MIN
1	Marc-Andre Fleury M. Fleury	339	1,051	1,017	575	2	95	29,821	27,188	.912	2,633	2.60	76	60668
2	Roberto Luongo R. Luongo	321	915	897	454	21	91	27,208	25,010	.919	2,198	2.49	67	52928
3	Henrik Lundqvist H. Lundqvist	310	887	871	459	0	96	25,610	23,509	.918	2,101	2.43	64	51816
4	Jonathan Quick J. Quick	290	804	786	404	0	88	21,670	19,731	.911	1,939	2.49	63	46660
5	Ryan Miller R. Miller	289	796	772	391	1	87	23,694	21,665	.914	2,029	2.64	44	46145
6	Craig Anderson C. Anderson	275	709	669	319	2	71	21,762	19,846	.912	1,916	2.86	43	40228
7	Mike Smith M. Smith	263	670	645	299	0	78	19,589	17,869	.912	1,720	2.70	44	38260
8	Carey Price C. Price	261	712	700	361	0	79	21,059	19,304	.917	1,755	2.51	49	42005
9	Cam Ward C. Ward	256	701	683	334	0	88	20,102	18,259	.908	1,843	2.74	27	40319
10	Sergei Bobrovsky S. Bobrovsky	243	754	740	429	0	57	21,796	19,928	.914	1,868	2.58	49	43525
11	Kari Lehtonen K. Lehtonen	233	649	619	310	0	67	18,920	17,258	.912	1,662	2.71	38	36838
12	Semyon Varlamov S. Varlamov	232	621	593	289	0	71	18,625	17,053	.916	1,572	2.65	41	35629
13	Martin Brodeur M. Brodeur	229	674	668	367	20	49	17,380	15,871	.913	1,509	2.27	70	39856
14	Tomas Vokoun T. Vokoun	219	563	551	261	21	43	16,732	15,382	.919	1,350	2.51	45	32283
15	John Gibson J. Gibson	217	506	494	204	0	63	15,420	14,033	.910	1,387	2.89	24	28803
16	Pekka Rinne P. Rinne	213	683	667	369	0	75	19,225	17,627	.917	1,598	2.43	60	39413
17	Jacob Markstrom J. Markstrom	212	534	517	241	0	63	15,106	13,720	.908	1,386	2.70	24	30758
18	Devan Dubnyk D. Dubnyk	206	542	514	253	0	54	15,532	14,194	.914	1,338	2.61	33	30793
19	Miikka Kiprusoff M. Kiprusoff	206	598	590	310	4	64	16,555	15,103	.912	1,452	2.49	42	34978
20	Jimmy Howard J. Howard	196	543	523	246	0	70	15,313	13,970	.912	1,343	2.62	24	30755
21	Cameron Talbot C. Talbot	195	533	508	266	0	47	15,392	14,043	.912	1,349	2.66	33	30424
22	Dwayne Roloson D. Roloson	192	459	435	186	19	40	13,316	12,138	.912	1,178	2.68	22	26379
23	Jaroslav Halak J. Halak	189	581	555	295	0	69	16,394	15,004	.915	1,390	2.50	53	33302
24	Nikolai Khabibulin N. Khabibulin	188	443	433	182	18	39	12,357	11,180	.905	1,177	2.76	18	25561
25	James Reimer J. Reimer	187	525	479	225	0	65	15,364	13,976	.910	1,388	2.89	31	28834