Between the 2001-02 and 2020-21 seasons, the San Jose Sharks had the most wins by a team, with 803 wins.

Interpreted as:

NHL most regular-season wins 2001-02 to 2020-21

	TEAM	W	GP	L	T	OTL	PTS	PTS%	SOW	SOL	G	GA	DIFF	PP%	PK%	S/GP	S%	SA/GP	SV%
1	Sharks	803	1,486	501	29	153	1,788	.602	76	67	4,285	3,904	381	19.7	82.7	31.04	9.3	28.45	.908
2	Bruins	797	1,486	480	32	177	1,803	.607	68	82	4,281	3,792	489	18.9	83.3	31.58	9.1	29.58	.914
3	Capitals	787	1,485	512	29	157	1,760	.593	68	71	4,429	4,184	245	20.4	81.2	29.60	10.1	30.47	.908
4	Penguins	782	1,485	539	22	142	1,728	.582	83	54	4,430	4,243	187	19.7	82.1	30.36	9.8	30.40	.906
5	Red Wings	777	1,487	502	31	177	1,762	.592	71	76	4,268	4,003	265	19.6	82.3	31.19	9.2	28.71	.906
6	Lightning	766	1,486	547	35	138	1,705	.574	68	59	4,369	4,214	155	19.1	81.6	29.71	9.9	29.54	.904
7	Blues	764	1,487	532	30	161	1,719	.578	74	69	4,072	3,911	161	18.3	83.2	29.22	9.4	27.76	.905
8	Predators	762	1,485	533	37	153	1,714	.577	74	70	4,081	3,937	144	17.0	82.2	29.44	9.3	29.74	.911
9	Stars	760	1,485	530	41	154	1,715	.577	73	62	4,118	3,963	155	18.1	81.8	29.45	9.4	28.49	.906
10	Canucks	755	1,485	556	30	144	1,684	.567	72	76	4,161	4,008	153	18.6	83.0	29.48	9.5	29.85	.910
11	Ducks	750	1,487	538	27	172	1,699	.571	71	78	3,964	3,926	38	18.2	82.8	29.22	9.1	29.92	.912
12	Rangers	747	1,486	569	21	149	1,664	.560	79	68	4,128	3,975	153	17.5	82.4	30.30	9.2	30.07	.911
13	Flyers	738	1,485	532	38	177	1,691	.569	53	92	4,280	4,150	130	19.0	81.9	30.59	9.4	29.40	.905
14	Avalanche	734	1,486	581	34	137	1,639	.551	73	42	4,208	4,168	40	18.5	81.5	29.72	9.5	30.29	.907
15	Wild	734	1,485	560	42	149	1,659	.559	71	70	3,927	3,855	72	17.7	83.4	27.88	9.5	29.56	.912
16	Canadiens	731	1,487	564	27	165	1,654	.556	69	66	4,057	4,043	14	18.5	82.4	29.76	9.2	30.75	.912
17	Devils	730	1,485	563	31	161	1,652	.556	78	84	3,749	3,826	-77	17.3	83.0	28.96	8.7	28.04	.908
18	Blackhawks	727	1,486	556	37	166	1,657	.558	75	70	4,230	4,173	57	17.0	81.6	30.92	9.2	29.73	.906
19	Flames	726	1,486	587	32	141	1,625	.547	52	65	4,058	4,082	-24	17.2	81.9	29.11	9.4	28.88	.905
20	Senators	722	1,487	575	27	163	1,634	.549	58	79	4,305	4,216	89	18.2	82.0	30.57	9.5	30.47	.907
21	Maple Leafs	714	1,486	579	27	166	1,621	.545	59	77	4,351	4,413	-62	18.7	80.3	30.12	9.7	30.66	.903
22	Kings	694	1,486	601	33	158	1,579	.531	69	71	3,868	3,951	-83	17.5	81.8	29.75	8.7	28.20	.906
23	Islanders	691	1,484	601	30	162	1,574	.530	86	70	4,070	4,321	-251	17.1	81.1	29.92	9.2	30.61	.905
24	Jets	687	1,487	627	26	147	1,547	.520	73	59	4,220	4,504	-284	17.7	80.2	29.21	9.7	31.52	.904
25	Hurricanes	685	1,484	587	41	171	1,582	.533	50	61	4,025	4,217	-192	16.8	81.9	31.17	8.7	29.28	.903