The Buffalo Sabres had their lowest moneyline in a game in 2021-22 against the Flyers on April 16, 2022, at -157.

	TEAM	DATE	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	G	GA	PPG	PPO	OPP PPG	OPP PPO	S	SA
1	Sabres	4/16/2022	BUF	-157	vs	PHI	+133	W 4-3	-1.5	-0.5 (N)	6.5	+0.5 (O)	4	3	2	4	0	4	29	21
2	Sabres	4/29/2022	BUF	-137	vs	CHI	+116	W 3-2	-1.5	-0.5 (N)	6.5	-1.5 (U)	3	2	0	3	0	1	36	21
3	Sabres	2/17/2022	BUF	-134	vs	OTT	+112	L 1-3	-1.5	-3.5 (N)	6	-2 (U)	1	3	1	6	0	2	24	28
4	Sabres	10/16/2021	BUF	-129	vs	ARI	+107	W 2-1	-1.5	-0.5 (N)	5.5	-2.5 (U)	1	1	1	2	0	2	33	21
5	Sabres	2/13/2022	BUF	-117	@	MTL	-104	W 5-3	-1.5	+0.5 (Y)	6	+2 (O)	5	3	1	3	0	3	32	32
6	Sabres	4/17/2022	BUF	-115	@	PHI	-105	W 5-3	-1.5	+0.5 (Y)	6.5	+1.5 (O)	5	3	2	2	0	2	40	35
7	Sabres	11/6/2021	BUF	-110	vs	DET	-110	L 3-4	+1.5	+0.5 (Y)	5.5	+1.5 (O)	3	4	1	2	0	1	32	33
8	Sabres	2/23/2022	BUF	-103	@	MTL	-117	L 0-4	+1.5	-2.5 (N)	6	-2 (U)	0	4	0	2	0	1	32	29
9	Sabres	1/6/2022	BUF	-102	vs	SJS	-118	L 2-3	+1.5	+0.5 (Y)	6	-1 (U)	2	3	1	3	0	1	39	21
10	Sabres	11/26/2021	BUF	-101	vs	MTL	-120	W 4-1	+1.5	+4.5 (Y)	6	-1 (U)	4	1	0	1	0	2	39	26
11	Sabres	2/10/2022	BUF	+101	vs	CBJ	-121	L 3-4	+1.5	+0.5 (Y)	6	+1 (O)	3	4	0	1	1	2	27	34
12	Sabres	10/31/2021	BUF	+104	@	LAK	-124	L 2-3	+1.5	+0.5 (Y)	5.5	-0.5 (U)	2	3	0	2	1	6	24	34
13	Sabres	4/23/2022	BUF	+107	vs	NYI	-127	W 5-3	+1.5	+3.5 (Y)	6	+2 (O)	5	3	1	6	0	2	35	22
14	Sabres	12/29/2021	BUF	+110	vs	NJD	-131	L 3-4	+1.5	+0.5 (Y)	6	+1 (O)	3	4	0	1	1	2	22	42
15	Sabres	11/22/2021	BUF	+111	vs	CBJ	-133	L 4-7	+1.5	-1.5 (N)	5.5	+5.5 (O)	4	7	2	4	0	3	33	29
16	Sabres	12/7/2021	BUF	+112	vs	ANA	-134	L 0-2	+1.5	-0.5 (N)	6	-4 (U)	0	2	0	3	0	1	25	23
17	Sabres	10/28/2021	BUF	+112	@	ANA	-135	W 4-3	+1.5	+2.5 (Y)	5.5	+1.5 (O)	4	3	1	2	0	1	29	37
18	Sabres	1/29/2022	BUF	+118	@	ARI	-140	W 3-1	+1.5	+3.5 (Y)	5.5	-1.5 (U)	3	1	1	3	1	2	35	28
19	Sabres	11/29/2021	BUF	+118	vs	SEA	-140	L 4-7	+1.5	-1.5 (N)	5.5	+5.5 (O)	4	7	1	4	0	0	36	32
20	Sabres	4/21/2022	BUF	+119	@	NJD	-141	W 5-2	+1.5	+4.5 (Y)	6.5	+0.5 (O)	5	2	0	1	0	4	28	31
21	Sabres	1/22/2022	BUF	+119	vs	PHI	-142	W 6-3	+1.5	+4.5 (Y)	5.5	+3.5 (O)	6	3	3	4	1	5	24	33
22	Sabres	10/14/2021	BUF	+122	vs	MTL	-145	W 5-1	+1.5	+5.5 (Y)	5.5	+0.5 (O)	5	1	3	6	0	4	36	31
23	Sabres	11/2/2021	BUF	+127	@	SJS	-150	L 3-5	+1.5	-0.5 (N)	5.5	+2.5 (O)	3	5	0	2	0	1	28	27
24	Sabres	3/30/2022	BUF	+128	vs	WPG	-151	L 2-3	+1.5	+0.5 (Y)	6	-1 (U)	2	2	0	2	0	1	37	27
25	Sabres	1/17/2022	BUF	+128	vs	DET	-149	L 2-3	+1.5	+0.5 (Y)	5.5	-0.5 (U)	2	3	0	2	0	1	28	35