Ed Marinaro has the most career rushing yards per game, with 174.6 per game.

most rush yds per game by a player aLL-TIME

	NAME	RUSH YDS/G	GP	RUSH YDS	ATT	YPC	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Ed Marinaro E. Marinaro	174.6	27	4,715	918	5.1	50	232	23		10.1	8.6	2
2	Garrett Wolfe G. Wolfe	159.8	34	5,434	849	6.4	54	588	58		10.1	17.3	5
3	Herschel Walker H. Walker	159.4	33	5,259	994	5.3	49	243	26		9.3	7.4	3
4	O.J. Simpson	156.2	20	3,124	621	5.0	33	235	28		8.4	11.8	0
5	LeShon Johnson L. Johnson	150.6	22	3,314	592	5.6	18	110	19		5.8	5.0	0
6	Jonathan Taylor J. Taylor	150.6	41	6,174	926	6.7	50	407	42	67	9.7	9.9	5
7	Cecil Collins C. Collins	149.0	4	596	72	8.3	3	11	1		11.0	2.8	0
8	Ron Dayne R. Dayne	148.8	43	6,397	1,115	5.7	63	304	31		9.8	7.1	0
9	George Jones G. Jones	147.9	19	2,810	486	5.8	34	238	34		7.0	12.5	0
10	Corey Dillon C. Dillon	141.4	11	1,555	271	5.7	22	273	15		18.2	24.8	1
11	Troy Davis T. Davis	141.4	31	4,382	782	5.6	36	258	33		7.8	8.3	1
12	Tony Dorsett T. Dorsett	138.2	44	6,082	1,074	5.7	55	404	38		10.6	9.2	4
13	LaMichael James L. James	137.4	37	5,082	771	6.6	53	586	51		11.5	15.8	4
14	DeAngelo Williams D. Williams	137.0	44	6,026	969	6.2	55	723	70		10.3	16.4	5
15	Mike Rozier M. Rozier	136.6	35	4,780	668	7.2	49	216	20		10.8	6.2	2
16	Ricky Williams R. Williams	136.5	46	6,279	1,011	6.2	72	927	85		10.9	20.2	3
17	Howard Stevens H. Stevens	136.2	20	2,723	509	5.3	25	389	51		7.6	19.5	4
18	Marshall Faulk M. Faulk	131.1	35	4,589	766	6.0	57	973	82		11.9	27.8	5
19	Rudi Johnson R. Johnson	130.6	12	1,567	324	4.8	13	70	9		7.8	5.8	0
20	Adrian Peterson A. Peterson	130.5	31	4,045	747	5.4	41	198	24		8.3	6.4	1
21	Amos Zereoue A. Zereoue	130.2	30	3,907	726	5.4	38	310	48		6.5	10.3	1
22	Kevin Smith K. Smith	130.0	36	4,679	905	5.2	45	444	55		8.1	12.3	1
23	Ryan Benjamin R. Benjamin	130.0	24	3,119	473	6.6	26	1,064	100		10.6	44.3	3
24	Ray Rice R. Rice	129.6	38	4,926	910	5.4	49	334	37		9.0	8.8	1
25	Alex Smith A. Smith	129.3	27	3,492	723	4.8	21	249	37		6.7	9.2	0