Since 1999-00, Gennaro Gattuso has made the most appearances by a Milan player in Serie A, with 335 appearances.

	NAME	M	MIN	START	G	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Gennaro Gattuso G. Gattuso	335	24,924	295	9	0.03	2	11	0
2	Clarence Seedorf C. Seedorf	300	22,345	256	47	0.16	7	54	0
3	Massimo Ambrosini M. Ambrosini	300	20,124	227	28	0.09	4	32	0
4	Andrea Pirlo A. Pirlo	284	22,495	250	32	0.11	2	34	14
5	Christian Abbiati C. Abbiati	263	22,942	258	0	0.00	0	0	0
6	Paolo Maldini P. Maldini	244	21,040	238	8	0.03			0
7	Ignazio Abate I. Abate	243	19,215	214	3	0.01	13	16	0
8	Andriy Shevchenko A. Shevchenko	226	17,174	195	127	0.56			24
9	Alessandro Nesta A. Nesta	224	19,010	217	7	0.03	0	7	0
10	Kaká	223	17,901	201	77	0.35	3	80	19
11	Gianluigi Donnarumma G. Donnarumma	215	19,093	215	0	0.00	0	0	0	0	1	1	0	8,181	3	0
12	Davide Calabria D. Calabria	210	15,480	175	9	0.04	17	26	0	0	141	35	2	13,344	190	9
13	Rafael Leão R. Leão	207	13,859	154	60	0.29	43	103	2	0	433	168	13	7,233	966	53
14	Dida	206	18,442	205	0	0.00			0
15	Filippo Inzaghi F. Inzaghi	202	11,716	122	73	0.36	0	73	1
16	Alessio Romagnoli A. Romagnoli	197	16,917	191	8	0.04	2	10	0	0	82	25	3	12,418	113	17
17	Theo Hernández T. Hernández	195	16,729	188	31	0.16	23	54	3	0	292	90	9	13,994	458	29
18	Kakha Kaladze K. Kaladze	194	15,774	177	12	0.06			0
19	Sérgio dos Santos S. dos Santos	185	11,333	120	18	0.10			2
20	Franck Kessié F. Kessié	174	14,741	165	36	0.21	10	46	21	0	248	86	7	10,911	473	10
21	Giacomo Bonaventura G. Bonaventura	155	11,522	129	31	0.20	23	54	0	2	344	111	9	8,629	224	22
22	Daniele Bonera D. Bonera	152	11,860	135	0	0.00	0	0	0
23	Fikayo Tomori F. Tomori	140	11,531	131	6	0.04	3	9	0	0	50	21	0	9,487	73	2
24	Alessandro Costacurta A. Costacurta	138	10,386	114	1	0.01			1
25	Ismael Bennacer I. Bennacer	137	8,808	101	7	0.05	7	14	1	0	74	16	1	7,911	58	2