Ryan Giggs has the most career assists by a player against a club in the Premier League, with 12 assists 2 times.

Interpreted as:

most assists by a player vs one club in pl history

	NAME	A	OPP	M	MIN	START	G	G/M	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Ryan Giggs R. Giggs	12	Newcastle	31	2,292	27	5	0.16	17	0
2	Ryan Giggs R. Giggs	12	Man City	29	1,947	21	1	0.03	13	0
3	Cesc Fàbregas C. Fàbregas	11	Tottenham	18	1,404	15	2	0.11	13	0
4	Steven Gerrard S. Gerrard	10	Man City	23	1,949	22	4	0.17	14	0
5	Kevin De Bruyne K. De Bruyne	9	Watford	9	674	8	1	0.11	10	0	0	24	8	1	669	39	1
6	Kevin De Bruyne K. De Bruyne	9	Southampton	14	1,052	12	4	0.29	13	0	0	33	10	1	1,005	49	1
7	Kevin De Bruyne K. De Bruyne	9	Crystal Palace	18	1,391	15	5	0.28	14	0	1	42	10	4	1,351	57	1
8	Mohamed Salah M. Salah	9	Newcastle	18	1,368	15	10	0.56	19	2
9	Frank Lampard F. Lampard	9	Bolton	23	2,005	22	12	0.52	21	2
10	Dennis Bergkamp D. Bergkamp	9	Leicester	12	960	11	5	0.42	14	1
11	Ryan Giggs R. Giggs	9	Chelsea	31	2,299	25	2	0.06	11	0
12	Andrew Robertson A. Robertson	8	Crystal Palace	17	1,357	16	0	0.00	8	0	0	13	3	0	1,435	34	1
13	Christian Eriksen C. Eriksen	8	Stoke City	10	843	10	2	0.20	10	0
14	Wayne Rooney W. Rooney	8	Newcastle	24	1,960	23	15	0.63	23	1
15	Thierry Henry T. Henry	8	Sunderland	11	800	9	7	0.64	15	0
16	Dennis Bergkamp D. Bergkamp	8	Aston Villa	18	1,338	16	2	0.11	10	0
17	Dennis Bergkamp D. Bergkamp	8	Everton	14	1,147	13	6	0.43	14	1
18	Dennis Wise D. Wise	8	Tottenham	17	1,530	17	1	0.06	9	0
19	Ryan Giggs R. Giggs	8	Liverpool	38	2,894	32	4	0.11	12	0
20	Darren Anderton D. Anderton	8	Everton	19	1,447	17	2	0.11	10	0
21	Bruno Fernandes B. Fernandes	7	Leicester	9	729	8	4	0.44	11	1	0	21	7	0	618	34	2
22	Mohamed Salah M. Salah	7	Brighton	17	1,414	16	10	0.59	17	3	0	75	31	1	732	158	7
23	Trent Alexander-Arnold T. Alexander-Arnold	7	Arsenal	15	1,117	13	0	0.00	7	0	0	17	2	2	1,010	17	2
24	Son Heung-min S. Heung-min	7	Southampton	17	1,116	14	11	0.65	18	1	0	36	22	2	620	76	4
25	Kevin De Bruyne K. De Bruyne	7	Liverpool	15	1,225	14	4	0.27	11	1	0	29	8	1	879	48	5