Between the 1999-00 and 2008-09 seasons, Raúl scored the most goals in the Champions League, with 53 goals.

most goals by a player in the 2000s

	NAME	G	M	MIN	START	G/M	PK
1	Raúl	53	96	8,276	93	0.55	1
2	Ruud van Nistelrooy R. van Nistelrooy	51	67	5,642	65	0.76	9
3	Thierry Henry T. Henry	43	96	7,682	86	0.45	3
4	Andriy Shevchenko A. Shevchenko	33	74	5,962	69	0.45	3
5	Filippo Inzaghi F. Inzaghi	30	51	3,537	41	0.59	1
6	Roy Makaay R. Makaay	29	61	4,595	52	0.48	3
7	Fernando Morientes F. Morientes	29	75	5,034	60	0.39	0
8	Didier Drogba D. Drogba	28	55	4,324	49	0.51	0
9	David Trezeguet D. Trezeguet	24	45	3,170	36	0.53	0
10	Rivaldo	24	61	4,790	54	0.39	6
11	Kaká	23	56	4,668	54	0.41	4
12	Hernán Crespo H. Crespo	23	59	3,821	44	0.39	0
13	Alessandro Del Piero A. Del Piero	22	56	4,070	47	0.39	2
14	Luís Figo L. Figo	22	92	7,380	88	0.24	10
15	Patrick Kluivert P. Kluivert	20	49	3,921	43	0.41	0
16	Steven Gerrard S. Gerrard	19	62	5,068	58	0.31	5
17	Giovane Élber G. Élber	19	54	3,846	44	0.35	0
18	Frank Lampard F. Lampard	18	65	5,595	63	0.28	2
19	Juninho Pernambucano J. Pernambucano	18	59	4,698	55	0.31	3
20	John Carew J. Carew	18	54	3,889	45	0.33	0
21	Lionel Messi L. Messi	17	33	2,452	28	0.52	1
22	Samuel Eto'o S. Eto'o	17	46	3,510	41	0.37	1
23	Claudio Pizarro C. Pizarro	16	57	3,835	45	0.28	0
24	Mário Jardel M. Jardel	16	27	2,392	27	0.59	0
25	Ryan Giggs R. Giggs	16	93	6,708	78	0.17	0