50 players are tied for the most wins in the Premier League against Big Six opponents this season, with 2 wins. The first three are Donyell Malen, Emiliano Buendía and Emiliano Martínez.
| NAME | W | SEASON | CLUB | RTG | M | MIN | START | G | G/M | A | G+A | PK | FK | SH | SOT | WOOD | TCH | TCH-BOX | OFF | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Malen | 2 | 2025-26 |  Aston Villa | 6.08 | 3 | 96 | 1 | 0 | 0.00 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 18 | 5 | 0 |
| 2 | | E. Buendía | 2 | 2025-26 | Aston Villa | 8.25 | 2 | 58 | 1 | 1 | 0.50 | 1 | 2 | 0 | 0 | 2 | 1 | 0 | 40 | 0 | 0 |
| 3 |  | E. Martínez | 2 | 2025-26 | Aston Villa | 6.51 | 3 | 270 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 156 | 0 | 0 |
| 4 | | E. Konsa | 2 | 2025-26 | Aston Villa | 7.27 | 3 | 270 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 212 | 2 | 0 |
| 5 | | I. Maatsen | 2 | 2025-26 | Aston Villa | 6.87 | 3 | 27 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 33 | 4 | 0 |
| 6 | | J. McGinn | 2 | 2025-26 | Aston Villa | 6.26 | 3 | 223 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 94 | 1 | 0 |
| 7 | | L. Digne | 2 | 2025-26 | Aston Villa | 6.93 | 3 | 243 | 3 | 0 | 0.00 | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 133 | 5 | 0 |
| 8 | | M. Cash | 2 | 2025-26 | Aston Villa | 7.18 | 3 | 270 | 3 | 1 | 0.33 | 0 | 1 | 0 | 0 | 5 | 2 | 1 | 191 | 0 | 0 |
| 9 |  | M. Rogers | 2 | 2025-26 | Aston Villa | 6.56 | 3 | 270 | 3 | 1 | 0.33 | 0 | 1 | 0 | 0 | 4 | 2 | 1 | 123 | 11 | 1 |
| 10 |  | O. Watkins | 2 | 2025-26 | Aston Villa | 6.68 | 3 | 189 | 2 | 0 | 0.00 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 74 | 13 | 1 |
| 11 | | R. Barkley | 2 | 2025-26 | Aston Villa | 6.46 | 3 | 55 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 34 | 2 | 0 |
| 12 | | B. Kamara | 2 | 2025-26 | Aston Villa | 7.23 | 3 | 270 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 189 | 0 | 0 |
| 13 | | P. Torres | 2 | 2025-26 | Aston Villa | 7.20 | 3 | 254 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 160 | 0 | 0 |
| 14 |  | A. Onana | 2 | 2025-26 | Aston Villa | 7.16 | 3 | 262 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 171 | 0 | 0 |
| 15 | | E. Guessand | 2 | 2025-26 | Aston Villa | 6.30 | 3 | 136 | 2 | 0 | 0.00 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 38 | 4 | 0 |
| 16 | | R. Lavia | 2 | 2025-26 |  Chelsea | 6.83 | 2 | 49 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 33 | 2 | 0 |
| 17 |  | A. Garnacho | 2 | 2025-26 | Chelsea | 7.33 | 2 | 141 | 2 | 0 | 0.00 | 0 | 0 | 0 | 0 | 2 | 1 | 1 | 73 | 13 | 0 |
| 18 |  | J. Gittens | 2 | 2025-26 | Chelsea | 6.48 | 2 | 39 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 2 | 1 | 0 | 29 | 4 | 0 |
| 19 | | F. Onyeka | 2 | 2025-26 |  Brentford | 6.83 | 3 | 26 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 19 | 0 | 0 |
| 20 | | V. Janelt | 2 | 2025-26 | Brentford | 6.28 | 3 | 86 | 0 | 0 | 0.00 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 69 | 4 | 0 |
| 21 | | M. Damsgaard | 2 | 2025-26 | Brentford | 5.84 | 3 | 228 | 3 | 0 | 0.00 | 1 | 1 | 0 | 0 | 2 | 2 | 0 | 146 | 3 | 0 |
| 22 |  | J. Pedro | 2 | 2025-26 | Chelsea | 7.28 | 3 | 255 | 3 | 1 | 0.33 | 0 | 1 | 0 | 0 | 6 | 5 | 0 | 117 | 14 | 1 |
| 23 |  | M. Cucurella | 2 | 2025-26 | Chelsea | 7.15 | 3 | 244 | 3 | 0 | 0.00 | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 185 | 6 | 0 |
| 24 |  | M. Caicedo | 2 | 2025-26 | Chelsea | 7.75 | 3 | 270 | 3 | 1 | 0.33 | 1 | 2 | 0 | 0 | 3 | 2 | 0 | 198 | 3 | 0 |
| 25 |  | P. Neto | 2 | 2025-26 | Chelsea | 6.14 | 3 | 167 | 3 | 0 | 0.00 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 80 | 4 | 0 |
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