Between the 2015-16 and 2021-22 seasons, Harry Kane had the most goals in the Premier League, with 159 goals.

Interpreted as:

most goals by a player in the 2015-16 to 2021-22

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Harry Kane H. Kane	159	234	20,324	229	0.68	41	200	26	0	907	401	31	9,160	1,023	148
2	Jamie Vardy J. Vardy	128	236	19,622	221	0.54	31	159	26	0	544	261	18	5,605	931	215
3	Mohamed Salah M. Salah	118	180	14,915	168	0.66	46	164	18	0	678	304	14	8,489	1,581	89
4	Sergio Agüero S. Agüero	106	155	11,244	132	0.68	24	130	17	0	565	231	22	5,706	798	99
5	Sadio Mané S. Mané	101	233	18,535	213	0.43	35	136	0	0	569	238	16	11,575	1,207	141
6	Son Heung-min S. Heung-min	93	232	16,167	185	0.40	46	139	1	1	502	232	18	9,251	935	127
7	Raheem Sterling R. Sterling	91	225	17,134	193	0.40	41	132	3	1	508	213	17	11,312	1,569	83
8	Romelu Lukaku R. Lukaku	79	166	13,027	143	0.48	18	97	3	1	412	193	15	5,635	573	107
9	Riyad Mahrez R. Mahrez	73	224	15,578	176	0.33	47	120	12	3	482	206	13	11,324	771	54
10	Roberto Firmino R. Firmino	71	231	17,292	198	0.31	46	117	2	0	533	227	13	11,426	1,074	67
11	Pierre-Emerick Aubameyang P. Aubameyang	68	128	10,304	115	0.53	16	84	9	1	310	141	12	4,153	547	81
12	Callum Wilson C. Wilson	61	170	13,049	148	0.36	17	78	11	0	304	125	7	4,313	700	135
13	Marcus Rashford M. Rashford	59	204	13,529	147	0.29	32	91	6	1	385	171	10	7,102	829	89
14	Gabriel Jesus G. Jesus	58	159	9,308	99	0.36	29	87	3	0	343	161	10	5,030	797	82
15	Kevin De Bruyne K. De Bruyne	57	207	15,952	182	0.28	83	140	4	3	516	185	26	15,202	605	22
16	Wilfried Zaha W. Zaha	57	233	19,762	223	0.24	24	81	7	0	408	149	10	11,722	1,143	112
17	Anthony Martial A. Martial	56	175	11,734	133	0.32	25	81	2	0	314	145	5	6,808	692	66
18	Michail Antonio M. Antonio	56	195	14,691	167	0.29	28	84	1	0	444	168	19	7,983	688	89
19	Alexandre Lacazette A. Lacazette	54	158	10,311	117	0.34	25	79	7	1	293	135	5	4,836	733	76
20	Joshua King J. King	53	204	14,491	167	0.26	17	70	13	0	323	126	8	7,012	651	50
21	Chris Wood C. Wood	51	161	12,131	142	0.32	7	58	4	0	284	136	10	4,339	544	165
22	Danny Ings D. Ings	51	135	9,175	109	0.38	15	66	7	0	273	118	11	3,740	540	54
23	Dele Alli D. Alli	51	192	13,789	156	0.27	34	85	3	0	337	134	8	9,485	551	36
24	Olivier Giroud O. Giroud	49	158	7,182	71	0.31	14	63	1	0	288	117	10	3,512	404	64
25	Richarlison	48	173	13,984	161	0.28	16	64	4	0	421	137	11	7,127	824	100