Between the 2009-10 and 2022-23 seasons, Ciro Immobile scored the most goals in Serie A, with 194 goals.

	NAME	G	M	MIN	START	G/M	A	G+A	PK	FK	SH	SOT	WOOD	TCH	TCH-BOX	OFF
1	Ciro Immobile C. Immobile	194	321	25,264	288	0.60	48	242	48
2	Fabio Quagliarella F. Quagliarella	141	410	27,731	318	0.34	34	175	31
3	Antonio Di Natale A. Di Natale	136	228	17,651	202	0.60	27	163	25
4	Gonzalo Higuaín G. Higuaín	125	224	17,108	193	0.56	29	154	12
5	Mauro Icardi M. Icardi	121	219	17,197	193	0.55	27	148	19
6	Dries Mertens D. Mertens	113	295	17,052	182	0.38	56	169	11
7	Domenico Berardi D. Berardi	113	297	23,665	277	0.38	73	186	42
8	Paulo Dybala P. Dybala	110	297	20,447	236	0.37	54	164	23
9	Duván Zapata D. Zapata	108	282	18,412	210	0.38	39	147	7
10	Edin Džeko E. Džeko	107	268	19,486	211	0.40	43	150	3	0	897	356	31	9,012	1,403	114
11	Andrea Belotti A. Belotti	106	301	21,403	234	0.35	31	137	26	0	745	284	30	9,364	1,055	200
12	Luis Muriel L. Muriel	101	310	16,980	183	0.33	42	143	17
13	Josip Iličić J. Iličić	96	339	21,792	251	0.28	59	155	13
14	Lorenzo Insigne L. Insigne	96	337	23,962	278	0.28	75	171	27
15	Rodrigo Palacio R. Palacio	93	357	25,804	288	0.26	51	144	4
16	Mattia Destro M. Destro	91	304	17,783	204	0.30	14	105	2
17	Edinson Cavani E. Cavani	91	138	11,406	128	0.66	12	103	17
18	Marek Hamšík M. Hamšík	82	339	26,085	310	0.24	64	146	5
19	Cristiano Ronaldo C. Ronaldo	81	98	8,441	94	0.83	15	96	23	1	554	218	17	5,059	647	92
20	Alessandro Matri A. Matri	80	280	15,339	167	0.29	14	94	6
21	Lautaro Martínez L. Martínez	79	173	11,251	127	0.46	20	99	9	0	541	211	14	4,859	904	61
22	Antonio Candreva A. Candreva	79	465	33,934	392	0.17	73	152	21
23	Zlatan Ibrahimovic Z. Ibrahimovic	76	125	9,354	107	0.61	29	105	19
24	Giampaolo Pazzini G. Pazzini	76	244	14,593	145	0.31	8	84	21
25	Alberto Gilardino A. Gilardino	75	233	17,848	199	0.32	13	88	7