The 2021 pitchers for the Twins included Jordan Balazovic, Jhoan Duran, Drew Strotman, José Berríos and Michael Pineda.

	NO.	NAME	POS	HEIGHT	WEIGHT	DOB	AGE	BIRTHPLACE
1		Andrew Albers A. Albers	P	6'1"	200	10/6/1985	35	North Battleford, Canada
2	66	Jorge Alcala J. Alcala	P	6'3"	205	7/28/1995	25	Bajos de Haina, Dominican Republic
3	41	Shaun Anderson S. Anderson	P	6'4"	225	10/29/1994	26	Coral Springs, FL
4	81	Jordan Balazovic J. Balazovic	P	6'5"	215	9/17/1998	22	Mississauga, Canada
5	85	Charlie Barnes C. Barnes	P	6'2"	190	10/1/1995	25	Sumter, SC
6	45	Kyle Barraclough K. Barraclough	P	6'3"	225	5/23/1990	31	Santa Clara, CA
7	17	José Berríos J. Berríos	P	6'0"	205	5/27/1994	27	Bayamon, Puerto Rico
8	41	Beau Burrows B. Burrows	P	6'2"	215	9/18/1996	24	Fort Worth, TX
9	48	Alex Colome A. Colome	P	6'1"	220	12/31/1988	32	Santo Domingo, Dominican Republic
10	53	Danny Coulombe D. Coulombe	P	5'10"	190	10/26/1989	31	St. Louis, MO
11	68	Randy Dobnak R. Dobnak	P	6'1"	230	1/17/1995	26	South Park, PA
12	21	Tyler Duffey T. Duffey	P	6'3"	220	12/27/1990	30	Houston, TX
13	59	Jhoan Duran J. Duran	P	6'5"	230	1/8/1998	23	Esperanza, Dominican Republic
14	51	Luke Farrell L. Farrell	P	6'6"	210	6/7/1991	30	Westlake, OH
15	33	John Gant J. Gant	P	6'3"	200	8/6/1992	28	Savannah, GA
16	57	Edgar Garcia E. Garcia	P	6'1"	180	10/4/1996	24	Palenque, Dominican Republic
17	32	Ralph Garza R. Garza	P	6'2"	195	4/6/1994	27	Edinburg, TX
18		Ian Gibaut I. Gibaut	P	6'3"	250	11/19/1993	27	Houston, TX
19	33	J.A. Happ	P	6'5"	205	10/19/1982	38	Peru, IL
20	83	Griffin Jax G. Jax	P	6'2"	195	11/22/1994	26	Phoenix, AZ
21	54	Derek Law D. Law	P	6'3"	215	9/14/1990	30	Pittsburgh, PA
22	18	Kenta Maeda K. Maeda	P	6'1"	184	4/11/1988	33	Osaka, Japan
23	49	Juan Minaya J. Minaya	P	6'4"	210	9/18/1990	30	Maimon, Dominican Republic
24	71	Jovani Moran J. Moran	P	6'1"	167	4/24/1997	24	Mayaguez, Puerto Rico
25	82	Bailey Ober B. Ober	P	6'9"	260	7/12/1995	25	Huntersville, NC