| NAME | SO | SEASON | TM | G | W | L | W% | GS | ERA | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | ERA- | FIP | FIP- | H/9 | PRAA | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | A. Wainwright | 213 | 2010 |  STL | 33 | 20 | 11 | .645 | 33 | 2.42 | 5 | 2 | 0 | 230.1 | 186 | 62 | 68 | 15 | 56 | 4 | 0 | 2 | 910 | 2 | 8.32 | 2.19 | 3.80 | 0.59 | 23.4 | 6.2 | 1.05 | .275 | 2.66 | 62 | 2.85 | 73 | 7.27 | 27.5 |
| 2 | | A. Wainwright | 184 | 2012 | STL | 32 | 14 | 13 | .519 | 32 | 3.94 | 3 | 2 | 0 | 198.2 | 196 | 87 | 96 | 15 | 52 | 6 | 0 | 3 | 831 | 5 | 8.34 | 2.36 | 3.54 | 0.68 | 22.1 | 6.3 | 1.25 | .315 | 4.35 | 102 | 3.09 | 80 | 8.88 | 17.1 |
| 3 | | A. Wainwright | 219 | 2013 | STL | 34 | 19 | 9 | .679 | 34 | 2.94 | 5 | 2 | 0 | 241.2 | 223 | 79 | 83 | 15 | 35 | 6 | 0 | 2 | 956 | 5 | 8.16 | 1.30 | 6.26 | 0.56 | 22.9 | 3.7 | 1.07 | .305 | 3.09 | 80 | 2.55 | 68 | 8.30 | 31.8 |
| 4 | | A. Wainwright | 179 | 2014 | STL | 32 | 20 | 9 | .690 | 32 | 2.38 | 5 | 3 | 0 | 227.0 | 184 | 60 | 64 | 10 | 50 | 7 | 0 | 5 | 898 | 4 | 7.10 | 1.98 | 3.58 | 0.40 | 19.9 | 5.6 | 1.03 | .267 | 2.54 | 66 | 2.88 | 79 | 7.30 | 19.6 |
| 5 | | A. Wainwright | 20 | 2015 | STL | 7 | 2 | 1 | .667 | 4 | 1.61 | 0 | 0 | 0 | 28.0 | 25 | 5 | 7 | 0 | 4 | 0 | 2 | 0 | 111 | 0 | 6.43 | 1.29 | 5.00 | 0.00 | 18.0 | 3.6 | 1.04 | .287 | 2.25 | 42 | 2.13 | 55 | 8.04 | 5.4 |
| 6 | | A. Wainwright | 161 | 2016 | STL | 33 | 13 | 9 | .591 | 33 | 4.62 | 1 | 1 | 0 | 198.2 | 220 | 102 | 108 | 22 | 59 | 5 | 0 | 4 | 847 | 1 | 7.29 | 2.67 | 2.73 | 1.00 | 19.0 | 7.0 | 1.40 | .330 | 4.89 | 113 | 3.92 | 96 | 9.97 | 3.5 |
| 7 | | A. Wainwright | 96 | 2017 | STL | 24 | 12 | 5 | .706 | 23 | 5.11 | 0 | 0 | 0 | 123.1 | 140 | 70 | 73 | 14 | 45 | 5 | 0 | 4 | 546 | 2 | 7.01 | 3.28 | 2.13 | 1.02 | 17.6 | 8.2 | 1.50 | .326 | 5.33 | 123 | 4.29 | 101 | 10.22 | -0.9 |
| 8 | | A. Wainwright | 40 | 2018 | STL | 8 | 2 | 4 | .333 | 8 | 4.46 | 0 | 0 | 0 | 40.1 | 41 | 20 | 21 | 5 | 18 | 2 | 0 | 1 | 181 | 1 | 8.93 | 4.02 | 2.22 | 1.12 | 22.1 | 9.9 | 1.46 | .310 | 4.69 | 116 | 4.27 | 107 | 9.15 | -1.4 |
| 9 | | A. Wainwright | 153 | 2019 | STL | 31 | 14 | 10 | .583 | 31 | 4.19 | 0 | 0 | 0 | 171.2 | 181 | 80 | 83 | 22 | 64 | 8 | 0 | 7 | 745 | 2 | 8.02 | 3.36 | 2.39 | 1.15 | 20.5 | 8.6 | 1.43 | .319 | 4.35 | 101 | 4.34 | 101 | 9.49 | -1.3 |
| Total | 1,265 | 234 | 116 | 71 | .620 | 230 | 3.48 | 19 | 10 | 0 | 1459.2 | 1,396 | 565 | 603 | 118 | 383 | 43 | 2 | 28 | 6,025 | 22 | 7.80 | 2.36 | 3.30 | 0.73 | 21.0 | 6.4 | 1.22 | .303 | 3.72 | 89 | 3.31 | 84 | 8.61 | 101.4 |
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