Between the 1999 and 2011 seasons, Alex Rodriguez launched the most home runs, with 523 home runs.

	NAME	HR	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Alex Rodriguez A. Rodriguez	523	1,889	7,129	1,441	2,127	360	18	1,541	1,012	138	1,530	208	48	8,363	4,092	901	1	83	86	181	.298	.392	.574	.966	1579	554.6	.408	149	517
2	Albert Pujols A. Pujols	445	1,705	6,312	1,291	2,073	455	15	1,329	975	77	704	84	35	7,433	3,893	915	1	68	251	232	.328	.420	.617	1.037	1538	641.3	.430	167	626.2
3	Jim Thome J. Thome	441	1,715	5,676	1,058	1,541	290	12	1,203	1,206	43	1,776	3	9	6,974	3,178	743	0	49	133	101	.271	.400	.560	.960	1298	438.7	.405	145	398.9
4	Manny Ramirez M. Ramirez	401	1,600	5,735	1,102	1,816	378	14	1,314	970	88	1,281	13	14	6,851	3,425	793	0	58	187	166	.317	.420	.597	1.017	1390	544.9	.424	158	507.3
5	Vladimir Guerrero V. Guerrero	399	1,889	7,180	1,174	2,285	418	37	1,346	676	89	848	167	81	8,001	3,974	854	0	56	235	250	.318	.381	.553	.935	1398	418.6	.391	137	376.2
6	Paul Konerko P. Konerko	389	1,917	6,961	1,019	1,976	360	8	1,232	793	86	1,141	9	3	7,916	3,519	757	1	75	74	236	.284	.361	.506	.866	1241	274.8	.371	123	223.5
7	Carlos Delgado C. Delgado	368	1,520	5,524	976	1,572	365	12	1,179	882	141	1,262	10	4	6,619	3,065	745	0	72	158	119	.285	.392	.555	.947	1192	369.7	.397	140	340.8
8	David Ortiz D. Ortiz	368	1,641	5,888	1,002	1,667	433	16	1,214	914	27	1,244	10	7	6,889	3,236	817	2	58	113	144	.283	.379	.550	.928	1202	365.8	.392	137	316.6
9	Andruw Jones A. Jones	366	1,759	6,279	1,017	1,614	318	26	1,082	760	84	1,412	102	44	7,184	3,082	710	0	61	58	168	.257	.342	.491	.833	1043	156.3	.356	113	120.9
10	Adam Dunn A. Dunn	365	1,570	5,390	901	1,312	282	10	922	1,065	75	1,809	59	22	6,561	2,709	657	2	29	107	85	.243	.374	.503	.876	1056	264	.375	126	216.1
11	Lance Berkman L. Berkman	358	1,774	6,154	1,107	1,822	405	28	1,193	1,149	64	1,229	84	48	7,422	3,357	791	1	54	154	137	.296	.409	.545	.954	1378	474.7	.405	146	432.9
12	Jason Giambi J. Giambi	355	1,614	5,139	927	1,429	275	6	1,102	1,099	154	1,163	16	6	6,456	2,781	636	0	64	80	105	.278	.415	.541	.957	1226	429.2	.409	150	411.8
13	Barry Bonds B. Bonds	351	1,088	3,226	863	1,018	198	14	780	1,201	56	489	69	11	4,506	2,297	563	0	23	399	55	.316	.505	.712	1.217	1144	580.9	.483	198	570.1
14	Carlos Lee C. Lee	349	1,952	7,433	1,072	2,128	442	18	1,286	597	46	935	122	47	8,171	3,653	809	3	92	56	193	.286	.339	.491	.831	1175	177.5	.355	114	140.4
15	Chipper Jones C. Jones	346	1,765	6,274	1,135	1,925	401	22	1,147	1,122	16	989	91	30	7,481	3,408	769	0	69	161	178	.307	.409	.543	.953	1384	465.7	.403	145	436.2
16	Alfonso Soriano A. Soriano	340	1,606	6,382	978	1,750	401	28	927	410	72	1,423	264	73	6,916	3,227	769	9	43	59	91	.274	.323	.506	.829	977	139.9	.351	111	98.6
17	Sammy Sosa S. Sosa	336	1,107	4,149	748	1,175	197	12	867	579	26	1,108	17	16	4,800	2,404	545	0	46	98	98	.283	.371	.579	.950	859	259.1	.395	138	239.5
18	Troy Glaus T. Glaus	319	1,489	5,245	870	1,339	284	10	927	839	46	1,326	55	29	6,173	2,600	613	0	43	40	135	.255	.360	.496	.856	958	195.8	.368	122	172.4
19	Todd Helton T. Helton	317	1,867	6,702	1,238	2,170	515	33	1,200	1,195	50	979	33	24	8,029	3,702	865	2	80	178	160	.324	.425	.552	.978	1560	575	.414	138	391
20	Mark Teixeira M. Teixeira	314	1,374	5,213	872	1,467	328	17	1,017	692	89	1,040	19	5	6,034	2,771	659	0	40	78	119	.281	.373	.532	.904	1017	291.2	.385	133	244.9
21	Derrek Lee D. Lee	313	1,779	6,454	1,010	1,839	400	29	1,000	818	60	1,478	99	46	7,387	3,236	742	2	53	71	186	.285	.368	.501	.869	1175	276.5	.373	125	234.8
22	Aramis Ramirez A. Ramirez	309	1,611	6,042	850	1,729	364	18	1,098	483	85	886	16	14	6,683	3,056	691	2	71	50	167	.286	.344	.506	.850	1003	191.6	.362	116	138
23	Gary Sheffield G. Sheffield	307	1,420	5,121	960	1,509	246	11	970	819	67	685	108	38	6,062	2,698	564	0	55	56	139	.295	.395	.527	.922	1080	328.7	.395	141	322.5
24	Adrian Beltre A. Beltre	303	1,882	7,166	976	1,991	421	28	1,091	529	60	1,182	111	39	7,829	3,377	752	12	62	65	187	.278	.330	.471	.801	1050	92.3	.343	110	93.7
25	Carlos Beltran C. Beltran	302	1,754	6,709	1,172	1,901	385	70	1,139	828	36	1,201	290	41	7,667	3,332	757	16	78	77	129	.283	.361	.497	.858	1179	239.2	.367	121	197