The Houston Astros scored their most runs in a game in 2025 versus the Dodgers on July 4, with 18 runs.

Interpreted as:

astros most runs in a regular-season game this year

	TEAM	R	DATE	TM		OPP	RESULT	AB	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Astros	18	7/4/2025	HOU	@	LAD	W 18-1	44	20	6	0	5	17	8	1	8	0	1	54	41	11	0	1	1	1	.455	.537	.932	1.469
2	Astros	14	4/11/2025	HOU	vs	LAA	W 14-3	38	17	1	0	3	13	8	0	3	3	0	48	27	4	0	2	0	0	.447	.521	.711	1.231
3	Astros	13	6/17/2025	HOU	@	ATH	W 13-3	40	15	3	0	5	12	7	3	4	0	2	50	33	8	0	0	0	1	.375	.500	.825	1.325
4	Astros	11	9/25/2025	HOU	@	ATH	W 11-5	39	12	4	0	1	11	7	1	10	1	0	47	19	5	0	0	0	0	.308	.426	.487	.913
5	Astros	11	9/12/2025	HOU	@	ATL	W 11-3	39	13	0	0	2	11	3	1	9	0	0	43	19	2	0	0	0	0	.333	.395	.487	.883
6	Astros	11	9/6/2025	HOU	@	TEX	W 11-0	44	15	3	1	2	11	4	1	12	0	0	49	26	6	0	0	0	0	.341	.408	.591	.999
7	Astros	11	7/20/2025	HOU	@	SEA	W 11-3	40	13	4	0	2	10	2	1	8	0	0	44	23	6	0	1	0	0	.325	.364	.575	.939
8	Astros	11	6/18/2025	HOU	@	ATH	W 11-4	45	20	2	0	3	11	3	0	8	0	0	48	31	5	0	0	0	2	.444	.479	.689	1.168
9	Astros	11	5/27/2025	HOU	vs	ATH	W 11-1	37	13	4	0	4	11	2	0	7	0	0	39	29	8	0	0	0	0	.351	.385	.784	1.168
10	Astros	10	8/22/2025	HOU	@	BAL	W 10-7	37	10	4	0	2	9	4	0	9	0	0	42	20	6	1	0	0	1	.270	.341	.541	.882
11	Astros	10	6/13/2025	HOU	vs	MIN	W 10-3	36	14	4	1	1	10	3	0	9	0	1	40	23	6	0	1	0	1	.389	.425	.639	1.064
12	Astros	10	6/11/2025	HOU	vs	CWS	W 10-2	37	15	7	0	1	9	3	0	9	1	0	40	25	8	0	0	0	1	.405	.450	.676	1.126
13	Astros	9	8/23/2025	HOU	@	BAL	W 9-8	38	11	2	0	4	8	2	0	5	0	0	40	25	6	0	0	0	0	.289	.325	.658	.983
14	Astros	9	7/30/2025	HOU	vs	WSH	W 9-1	32	10	0	0	3	9	2	1	7	0	1	36	19	3	0	1	0	0	.313	.361	.594	.955
15	Astros	9	5/22/2025	HOU	vs	SEA	W 9-2	35	13	0	1	2	9	2	3	6	0	0	41	21	3	0	1	0	1	.371	.439	.600	1.039
16	Astros	9	5/10/2025	HOU	vs	CIN	L 9-13	40	14	3	1	1	9	7	0	10	1	0	47	22	5	0	0	0	1	.350	.447	.550	.997
17	Astros	9	5/7/2025	HOU	@	MIL	W 9-1	35	8	3	0	1	8	7	0	5	0	0	43	14	4	1	0	0	1	.229	.357	.400	.757
18	Astros	9	4/6/2025	HOU	@	MIN	W 9-7	40	13	2	0	1	7	4	1	9	3	1	47	18	3	1	1	0	1	.325	.391	.450	.841
19	Astros	8	9/3/2025	HOU	vs	NYY	W 8-7	33	11	3	0	1	6	4	0	8	0	0	38	17	4	0	1	0	1	.333	.395	.515	.910
20	Astros	8	9/1/2025	HOU	vs	LAA	W 8-3	35	12	4	0	2	8	5	0	9	5	0	40	22	6	0	0	1	1	.343	.425	.629	1.054
21	Astros	8	8/4/2025	HOU	@	MIA	W 8-2	38	11	5	0	0	8	1	1	7	1	0	40	16	5	0	0	0	0	.289	.325	.421	.746
22	Astros	8	6/22/2025	HOU	@	LAA	W 8-7	39	13	2	0	3	7	4	0	7	2	1	44	24	5	0	1	0	0	.333	.386	.615	1.002
23	Astros	8	6/5/2025	HOU	@	PIT	W 8-2	36	10	2	0	2	8	2	0	7	3	0	39	18	4	0	1	0	0	.278	.308	.500	.808
24	Astros	8	5/3/2025	HOU	@	CWS	W 8-3	39	13	3	1	2	8	2	0	9	1	0	41	24	6	0	0	0	2	.333	.366	.615	.981
25	Astros	8	4/28/2025	HOU	vs	DET	W 8-5	33	10	2	0	2	8	2	0	5	0	0	35	18	4	0	0	0	2	.303	.343	.545	.888