The Houston Astros have a 28-25 record on September 21 all-time.

	TEAM	DATE	REC	TM		OPP	RESULT	W%	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Colt .45's	9/21/1962	0-1	HOU	vs	SFG	L 5-11	.000	38	5	12	2	1	0	5	2	0	4	0	0	41	16	3	0	1	0	1	.316	.341	.421	.763
2	Colt .45's	9/21/1963	0-1	HOU	vs	PHI	L 3-4	.000	32	3	7	1	0	1	3	1	0	1	0	0	34	11	2	0	1	0	1	.219	.235	.344	.579
3	Colt .45's	9/21/1964	1-0	HOU	vs	SFG	W 3-1	1.000	26	3	6	1	0	1	3	2	0	7	0	1	30	10	2	1	1	0	0	.231	.276	.385	.660
4	Astros	9/21/1965	0-1	HOU	@	STL	L 0-3	.000	30	0	5	1	0	0	0	5	0	9	1	1	35	6	1	0	0	0	1	.167	.286	.200	.486
5	Astros	9/21/1968	0-1	HOU	vs	CIN	L 0-5	.000	30	0	4	3	0	0	0	3	0	10	0	0	33	7	3	0	0	0	1	.133	.212	.233	.445
6	Astros	9/21/1969	0-1	HOU	vs	CIN	L 1-4	.000	28	1	4	0	0	0	1	9	0	4	2	0	38	4	0	1	0	0	2	.143	.351	.143	.494
7	Astros	9/21/1970	0-1	HOU	@	CIN	L 0-2	.000	30	0	4	1	0	0	0	2	0	12	1	1	32	5	1	0	0	0	0	.133	.188	.167	.354
8	Astros	9/21/1971	1-0	HOU	vs	SFG	W 3-1	1.000	27	3	6	2	0	1	3	3	0	4	0	1	31	11	3	1	0	0	1	.222	.300	.407	.707
9	Astros	9/21/1974	1-0	HOU	vs	ATL	W 6-5	1.000	37	6	11	1	1	1	6	5	0	4	3	0	42	17	3	0	0	1	1	.297	.381	.459	.840
10	Astros	9/21/1975	1-0	HOU	vs	LAD	W 4-1	1.000	30	4	10	0	0	0	4	1	0	1	2	0	32	10	0	0	1	0	2	.333	.344	.333	.677
11	Astros	9/21/1976	0-1	HOU	vs	ATL	L 2-6	.000	36	2	9	0	0	0	2	2	0	5	0	0	38	9	0	0	0	0	1	.250	.289	.250	.539
12	Astros	9/21/1977	0-1	HOU	vs	ATL	L 3-5	.000	35	3	8	1	1	0	2	2	0	10	5	0	37	11	2	0	0	0	0	.229	.270	.314	.585
13	Astros	9/21/1978	1-0	HOU	vs	ATL	W 2-0	1.000	35	2	11	1	0	0	2	0	0	4	0	0	35	12	1	0	0	0	0	.314	.314	.343	.657
14	Astros	9/21/1979	1-0	HOU	vs	CIN	W 3-2	1.000	47	3	13	1	0	0	3	3	0	5	1	3	52	14	1	2	0	2	1	.277	.320	.298	.618
15	Astros	9/21/1980	1-0	HOU	@	SFG	W 5-1	1.000	36	5	10	3	0	1	5	4	0	6	0	1	41	16	4	1	0	0	0	.278	.350	.444	.794
16	Astros	9/21/1982	1-0	HOU	vs	ATL	W 5-3	1.000	33	5	9	1	0	0	3	3	0	4	0	1	36	10	1	0	0	0	0	.273	.333	.303	.636
17	Astros	9/21/1983	0-1	HOU	@	LAD	L 1-2	.000	31	1	6	0	0	0	1	3	0	7	2	0	35	6	0	1	0	1	1	.194	.265	.194	.458
18	Astros	9/21/1984	0-1	HOU	vs	CIN	L 2-5	.000	32	2	6	2	2	0	2	3	0	6	1	0	35	12	4	0	0	0	0	.188	.257	.375	.632
19	Astros	9/21/1985	1-0	HOU	vs	CIN	W 9-5	1.000	37	9	13	3	1	1	8	4	0	8	2	0	41	21	5	0	0	1	0	.351	.415	.568	.982
20	Astros	9/21/1986	0-1	HOU	vs	SDP	L 0-5	.000	28	0	1	0	1	0	0	0	0	5	0	0	28	3	1	0	0	0	0	.036	.036	.107	.143
21	Astros	9/21/1988	1-0	HOU	vs	ATL	W 1-0	1.000	28	1	7	2	0	0	1	1	0	5	0	2	30	9	2	1	0	0	0	.250	.276	.321	.597
22	Astros	9/21/1989	0-1	HOU	@	ATL	L 0-3	.000	28	0	3	0	0	0	0	2	0	7	0	1	30	3	0	0	0	0	1	.107	.167	.107	.274
23	Astros	9/21/1990	1-0	HOU	@	ATL	W 4-3	1.000	36	4	7	3	0	2	4	6	0	10	0	1	42	16	5	0	0	0	0	.194	.310	.444	.754
24	Astros	9/21/1991	0-1	HOU	vs	CIN	L 1-4	.000	30	1	3	2	0	0	1	3	0	9	0	0	33	5	2	0	0	0	0	.100	.182	.167	.348
25	Astros	9/21/1993	1-0	HOU	vs	SFG	W 6-0	1.000	30	6	10	3	0	0	5	4	1	2	0	0	38	13	3	1	2	2	1	.333	.405	.433	.839
	Total		28-25					.528	1,767	217	452	85	10	49	205	166	11	342	41	18	1,972	704	144	15	13	12	39	.256	.321	.398	.720