| TEAM | BB | SEASON | G | W% | W | L | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | HBP | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Astros | 548 | 2010 | 162 | .469 | 76 | 86 | 162 | 4.09 | 1,210 | 4 | 2 | 45 | 1439.1 | 1,446 | 654 | 729 | 140 | 40 | 39 | 6,221 | 57 | 7.57 | 3.43 | 2.21 | 0.88 | 19.5 | 8.8 | 1.39 | .305 | 4.56 | 9.04 | |
| 2 | Astros | 560 | 2011 | 162 | .346 | 56 | 106 | 162 | 4.51 | 1,191 | 2 | 0 | 25 | 1435.0 | 1,477 | 719 | 796 | 188 | 53 | 59 | 6,268 | 39 | 7.47 | 3.51 | 2.13 | 1.18 | 19.0 | 8.9 | 1.42 | .301 | 4.99 | 9.26 | |
| 3 | Astros | 540 | 2012 | 162 | .340 | 55 | 107 | 162 | 4.56 | 1,170 | 3 | 2 | 31 | 1423.1 | 1,493 | 721 | 794 | 173 | 48 | 40 | 6,238 | 75 | 7.40 | 3.41 | 2.17 | 1.09 | 18.8 | 8.7 | 1.43 | .306 | 5.02 | 9.44 | |
| 4 | Astros | 616 | 2013 | 162 | .315 | 51 | 111 | 162 | 4.79 | 1,084 | 2 | 1 | 32 | 1440.0 | 1,530 | 766 | 848 | 191 | 56 | 32 | 6,370 | 61 | 6.78 | 3.85 | 1.76 | 1.19 | 17.0 | 9.7 | 1.49 | .303 | 5.30 | 9.56 | |
| 5 | Astros | 484 | 2014 | 162 | .432 | 70 | 92 | 162 | 4.11 | 1,137 | 7 | 2 | 31 | 1438.2 | 1,437 | 657 | 723 | 139 | 52 | 32 | 6,154 | 57 | 7.11 | 3.03 | 2.35 | 0.87 | 18.5 | 7.9 | 1.34 | .299 | 4.52 | 8.99 | |
| 6 | Astros | 423 | 2015 | 162 | .531 | 86 | 76 | 162 | 3.57 | 1,280 | 5 | 3 | 39 | 1441.0 | 1,308 | 572 | 618 | 148 | 43 | 17 | 5,965 | 61 | 7.99 | 2.64 | 3.03 | 0.92 | 21.5 | 7.1 | 1.20 | .285 | 3.86 | 8.17 | |
| 7 | Astros | 453 | 2016 | 162 | .519 | 84 | 78 | 162 | 4.06 | 1,396 | 2 | 1 | 44 | 1468.0 | 1,441 | 663 | 701 | 181 | 39 | 19 | 6,180 | 98 | 8.56 | 2.78 | 3.08 | 1.11 | 22.6 | 7.3 | 1.29 | .306 | 4.30 | 8.83 | |
| 8 | Astros | 522 | 2017 | 162 | .623 | 101 | 61 | 162 | 4.12 | 1,593 | 1 | 0 | 45 | 1446.0 | 1,314 | 662 | 700 | 192 | 70 | 17 | 6,111 | 86 | 9.91 | 3.25 | 3.05 | 1.20 | 26.1 | 8.5 | 1.27 | .300 | 4.36 | 8.18 | |
| 9 | Astros | 435 | 2018 | 162 | .636 | 103 | 59 | 162 | 3.11 | 1,687 | 2 | 2 | 46 | 1455.0 | 1,164 | 503 | 534 | 152 | 66 | 4 | 5,913 | 67 | 10.44 | 2.69 | 3.88 | 0.94 | 28.5 | 7.4 | 1.10 | .283 | 3.30 | 7.20 | |
| 10 | Astros | 448 | 2019 | 162 | .660 | 107 | 55 | 162 | 3.66 | 1,671 | 2 | 1 | 47 | 1462.1 | 1,205 | 595 | 640 | 230 | 41 | 0 | 5,995 | 41 | 10.28 | 2.76 | 3.73 | 1.42 | 27.9 | 7.5 | 1.13 | .270 | 3.94 | 7.42 | |
| 11 | Astros | 217 | 2020 | 60 | .483 | 29 | 31 | 60 | 4.31 | 526 | 0 | 0 | 16 | 524.0 | 472 | 251 | 275 | 70 | 29 | 7 | 2,239 | 25 | 9.03 | 3.73 | 2.42 | 1.20 | 23.5 | 9.7 | 1.31 | .288 | 4.72 | 8.11 | |
| 12 | Astros | 549 | 2021 | 162 | .586 | 95 | 67 | 162 | 3.78 | 1,456 | 2 | 0 | 34 | 1445.0 | 1,231 | 607 | 658 | 187 | 70 | 12 | 6,060 | 72 | 9.07 | 3.42 | 2.65 | 1.16 | 24.0 | 9.1 | 1.23 | .275 | 4.10 | 7.67 | |
| 13 | Astros | 458 | 2022 | 162 | .654 | 106 | 56 | 162 | 2.90 | 1,524 | 3 | 1 | 53 | 1445.1 | 1,121 | 465 | 518 | 134 | 60 | 6 | 5,856 | 56 | 9.49 | 2.85 | 3.33 | 0.83 | 26.0 | 7.8 | 1.09 | .268 | 3.23 | 6.98 | |
| 14 | Astros | 537 | 2023 | 162 | .556 | 90 | 72 | 162 | 3.94 | 1,460 | 2 | 2 | 41 | 1445.1 | 1,312 | 632 | 698 | 201 | 75 | 6 | 6,110 | 37 | 9.09 | 3.34 | 2.72 | 1.25 | 23.9 | 8.8 | 1.28 | .290 | 4.35 | 8.17 | |
| 15 | Astros | 544 | 2024 | 161 | .547 | 88 | 73 | 161 | 3.74 | 1,479 | 2 | 1 | 43 | 1432.0 | 1,238 | 595 | 649 | 183 | 61 | 2 | 6,018 | 49 | 9.30 | 3.42 | 2.72 | 1.15 | 24.6 | 9.0 | 1.24 | .281 | 4.08 | 7.78 | |
| 16 | Astros | 508 | 2025 | 162 | .537 | 87 | 75 | 162 | 3.86 | 1,504 | 3 | 0 | 45 | 1442.0 | 1,257 | 619 | 665 | 199 | 58 | 7 | 6,041 | 38 | 9.39 | 3.17 | 2.96 | 1.24 | 24.9 | 8.4 | 1.22 | .280 | 4.15 | 7.85 | |
| Total | 7,842 | 2,489 | .516 | 1,284 | 1,205 | 2,489 | 3.93 | 21,368 | 42 | 18 | 617 | 22182.1 | 20,446 | 9,681 | 10,546 | 2,708 | 861 | 299 | 93,739 | 919 | 8.67 | 3.18 | 2.72 | 1.10 | 22.8 | 8.4 | 1.28 | .291 | 4.28 | 8.30 |