Nolan Ryan has struck out the most career hitters, with 5,714 strikeouts.

	NAME	SO	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS	wRC	WRAA	wOBA	wRC+	BRAA
1	Nolan Ryan N. Ryan	5,714	424	852	40	94	10	2	2	36	38	0	3	3	957	114	14	65	2	0	11	.110	.148	.134	.282	-28	-132.4	.135	-21	-130.1
2	Randy Johnson R. Johnson	4,875	273	625	20	78	14	0	1	40	19	2	0	0	691	95	15	44	1	0	10	.125	.153	.152	.305	-25	-111.3	.140	-31	-117.3
3	Roger Clemens R. Clemens	4,672	95	179	5	31	6	0	0	12	13	2	0	0	213	37	6	18	1	0	3	.173	.236	.207	.443	4	-22.6	.207	14	-23.7
4	Steve Carlton S. Carlton	4,136	699	1,719	123	346	49	6	13	140	41	10	2	2	1,877	446	68	94	13	0	33	.201	.223	.259	.482	69	-134.3	.220	31	-146.8
5	Bert Blyleven B. Blyleven	3,701	216	451	19	59	7	0	0	25	5	2	0	0	514	66	7	56	0	0	4	.131	.144	.146	.290	-15	-70.1	.134	-28	-73.2
6	Tom Seaver T. Seaver	3,640	580	1,315	99	202	28	5	12	86	108	4	4	0	1,552	276	45	121	4	0	22	.154	.219	.210	.429	40	-126.1	.205	24	-132.9
7	Don Sutton D. Sutton	3,574	611	1,354	64	195	15	1	0	64	60	6	1	0	1,559	212	16	136	3	0	29	.144	.183	.157	.340	-10	-177.8	.162	-1	-178.7
8	Justin Verlander J. Verlander	3,553	24	50	2	5	0	0	0	1	0	0	0	0	60	5	0	10	0	0	2	.100	.100	.100	.200	-5	-11.9	.088	-66	-12.1
9	Gaylord Perry G. Perry	3,534	510	1,076	48	141	17	0	6	47	22	6	0	0	1,220	176	23	113	3	0	20	.131	.153	.164	.316	-20	-147.7	.146	-13	-154.9
10	Walter Johnson W. Johnson	3,509	934	2,324	241	547	94	41	24	255	110	13	13		2,517	795	159	70				.235	.274	.342	.616	214	-62.8	.293	74	-75.1
11	Max Scherzer M. Scherzer	3,489	238	464	31	78	6	0	1	30	13	2	3	0	529	87	7	49	1	0	5	.168	.194	.188	.381	-2	-64.4	.172	-3	-68.3
12	Greg Maddux G. Maddux	3,371	737	1,591	103	272	35	2	5	84	34	5	11	3	1,812	326	42	180	2	0	15	.171	.191	.205	.395	-1	-219.7	.179	-1	-228
13	Phil Niekro P. Niekro	3,342	732	1,537	80	260	42	1	7	109	17	12	0	1	1,707	325	50	129	12	0	35	.169	.183	.211	.395	11	-173.3	.180	0	-193.6
14	Fergie Jenkins F. Jenkins	3,192	410	896	54	148	27	6	13	85	41	0	0	1	1,010	226	46	66	7	0	9	.165	.200	.252	.452	28	-77.4	.207	19	-93.2
15	Pedro Martinez P. Martinez	3,154	277	434	22	43	6	2	0	18	15	3	0	0	518	53	8	63	3	0	5	.099	.134	.122	.256	-27	-90.9	.121	-40	-92.1
16	Bob Gibson B. Gibson	3,117	596	1,328	132	274	44	5	24	144	63	8	13	10	1,489	400	73	72	18	0	13	.206	.243	.301	.545	89	-69.6	.247	49	-86.2
17	Curt Schilling C. Schilling	3,116	402	773	39	117	13	1	0	29	25	0	1	1	901	132	14	102	1	0	8	.151	.178	.171	.348	-16	-127.1	.161	-16	-132.4
18	CC Sabathia	3,093	48	121	7	25	3	0	3	15	2	0	0	0	127	37	6	4	0	0	7	.207	.220	.306	.525	5	-10.3	.229	30	-10.8
19	John Smoltz J. Smoltz	3,084	709	948	77	151	26	2	5	61	79	3	3	2	1,167	196	33	136	1	0	15	.159	.226	.207	.433	23	-117.1	.205	14	-122.4
20	Clayton Kershaw C. Kershaw	3,052	357	698	46	113	11	1	1	40	34	4	1	0	847	129	13	110	1	0	15	.162	.205	.185	.390	1	-97.2	.180	5	-97.2
21	Zack Greinke Z. Greinke	2,979	260	521	49	117	29	1	9	34	26	2	9	1	600	175	39	47	4	0	8	.225	.262	.336	.598	42	-27	.261	59	-29.9
22	Jim Bunning J. Bunning	2,855	601	1,275	82	213	21	4	7	75	34	1	0	2	1,401	263	32	85	6	0	36	.167	.188	.206	.395	12	-141.2	.180	6	-153.9
23	Mickey Lolich M. Lolich	2,832	477	821	63	90	5	2	0	31	105	5	1	1	1,017	99	7	85	1	0	20	.110	.215	.121	.335	6	-99.6	.174	4	-107.7
24	Mike Mussina M. Mussina	2,813	22	52	3	9	1	0	0	5	1	0	0	0	54	10	1	1	0	0	0	.173	.189	.192	.381	0	-7.1	.172	-2	-7.1
25	Cy Young C. Young	2,803	918	2,960	325	623	87	35	18	290	81	10	29		3,101	834	140	50				.210	.234	.282	.516	198	-212.2	.245	45	-238.4