Sean Murphy had his most strikeouts in a game against the Rangers on May 28, 2022, with 4 strikeouts.

Interpreted as:

batters with most strikeouts in a regular-season game seasln

	NAME	SO	DATE	TM		OPP	AB	R	H	2B	3B	HR	RBI	BB	HBP	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP
1	Sean Murphy S. Murphy	4	5/28/2022	OAK	vs	TEX	5	0	0	0	0	0	0	0	0	0	0	5	0	0	0	0	0	0
2	Sean Murphy S. Murphy	3	8/17/2025	ATL	@	CLE	3	0	0	0	0	0	0	1	0	0	0	4	0	0	0	0	0	0
3	Sean Murphy S. Murphy	3	7/10/2025	ATL	@	ATH	4	1	1	1	0	0	1	0	0	0	0	4	2	1	0	0	0	0
4	Sean Murphy S. Murphy	3	7/2/2025	ATL	vs	LAA	4	1	1	0	0	1	3	0	0	0	0	4	4	1	0	0	0	0
5	Sean Murphy S. Murphy	3	6/26/2025	ATL	@	NYM	3	0	0	0	0	0	0	0	0	0	0	3	0	0	0	0	0	0
6	Sean Murphy S. Murphy	3	6/1/2025	ATL	vs	BOS	3	0	0	0	0	0	0	1	0	0	0	4	0	0	0	0	0	0
7	Sean Murphy S. Murphy	3	4/28/2025	ATL	@	COL	5	0	2	0	0	0	1	0	0	0	0	5	2	0	0	0	0	0
8	Sean Murphy S. Murphy	3	4/25/2025	ATL	@	AZ	4	1	1	1	0	0	0	1	0	0	0	5	2	1	0	0	0	0
9	Sean Murphy S. Murphy	3	4/15/2025	ATL	@	TOR	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
10	Sean Murphy S. Murphy	3	4/10/2025	ATL	vs	PHI	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
11	Sean Murphy S. Murphy	3	7/30/2023	ATL	vs	MIL	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
12	Sean Murphy S. Murphy	3	7/7/2023	ATL	@	TBR	4	1	1	0	0	1	2	0	0	0	0	4	4	1	0	0	0	0
13	Sean Murphy S. Murphy	3	5/12/2023	ATL	@	TOR	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
14	Sean Murphy S. Murphy	3	4/16/2023	ATL	@	KCR	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
15	Sean Murphy S. Murphy	3	8/4/2022	OAK	@	LAA	5	1	1	1	0	0	2	0	0	0	0	5	2	1	0	0	0	0
16	Sean Murphy S. Murphy	3	6/4/2022	OAK	vs	BOS	3	0	0	0	0	0	0	0	0	0	0	3	0	0	0	0	0	0
17	Sean Murphy S. Murphy	3	5/22/2022	OAK	@	LAA	4	0	1	0	0	0	0	0	0	0	0	4	1	0	0	0	0	0
18	Sean Murphy S. Murphy	3	4/26/2022	OAK	@	SFG	3	0	0	0	0	0	0	1	0	0	0	4	0	0	0	0	0	0
19	Sean Murphy S. Murphy	3	4/12/2022	OAK	@	TBR	4	1	0	0	0	0	0	1	0	0	0	5	0	0	0	0	0	0
20	Sean Murphy S. Murphy	3	9/1/2021	OAK	@	DET	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
21	Sean Murphy S. Murphy	3	8/27/2021	OAK	vs	NYY	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
22	Sean Murphy S. Murphy	3	8/26/2021	OAK	vs	NYY	4	1	1	0	0	1	1	0	0	0	0	4	4	1	0	0	0	0
23	Sean Murphy S. Murphy	3	4/6/2021	OAK	vs	LAD	4	0	0	0	0	0	0	0	0	0	0	4	0	0	0	0	0	0
24	Sean Murphy S. Murphy	3	9/22/2020	OAK	@	LAD	3	1	0	0	0	0	0	1	0	0	0	4	0	0	0	0	0	0
25	Sean Murphy S. Murphy	3	8/23/2020	OAK	vs	LAA	4	0	1	0	0	0	1	0	0	0	0	4	1	0	0	0	0	0

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Results may be incomplete. StatMuse has complete game-level data for strikeouts going back to the 1916 season.

Some of the information used here was obtained free of charge from Retrosheet.

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Mon 3/30	ATH	@	ATL	7:15 PM
Tue 3/31	ATH	@	ATL	7:15 PM
Wed 4/1	ATH	@	ATL	12:15 PM
Fri 4/3	HOU	@	ATH	9:40 PM
Sat 4/4	HOU	@	ATH	4:05 PM

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Cardinals	2	1	.667	1.0
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Pirates	1	2	.333	2.0
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Dodgers	3	0	1.000
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White Sox	0	3	.000	2.0
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Astros	2	2	.500	0.5
Angels	2	2	.500	0.5
Mariners	2	2	.500	0.5
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