Since June 13, 2025, the Milwaukee Brewers have the highest run differential by a team, with a differential of 150 runs.

	TEAM	DIFF	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Brewers	150	92	.652	60	32	3,185	501	874	172	11	103	468	323	45	695	78	33	3,598	1,377	286	11	34	7	62	.274	.346	.432	.779
2	Phillies	113	94	.606	57	37	3,201	466	838	164	14	141	457	290	36	802	62	17	3,563	1,453	319	9	27	11	53	.262	.328	.454	.781
3	Red Sox	92	92	.598	55	37	3,118	441	791	188	15	98	417	277	39	769	78	24	3,469	1,303	301	8	27	10	64	.254	.320	.418	.738
4	Mariners	86	95	.600	57	38	3,210	475	792	149	5	151	452	305	56	845	96	18	3,610	1,404	305	14	25	24	61	.247	.321	.437	.758
5	Dodgers	74	93	.559	52	41	3,106	444	755	140	9	139	426	321	32	780	46	13	3,499	1,330	288	10	30	18	56	.243	.318	.428	.746
6	Blue Jays	73	94	.596	56	38	3,210	502	871	175	10	121	486	295	43	637	39	14	3,590	1,429	306	19	23	13	81	.271	.339	.445	.784
7	Yankees	57	95	.547	52	43	3,195	483	780	135	9	166	468	365	24	876	83	23	3,618	1,431	310	5	29	29	61	.244	.324	.448	.771
8	Padres	57	95	.547	52	43	3,194	423	818	159	8	95	406	298	41	687	54	17	3,589	1,278	262	31	25	12	62	.256	.325	.400	.725
9	Rangers	56	93	.516	48	45	3,189	429	762	160	9	100	410	303	40	768	72	16	3,563	1,240	269	8	23	15	59	.239	.311	.389	.700
10	Cubs	40	93	.538	50	43	3,097	414	756	141	14	127	400	307	29	727	77	20	3,470	1,306	282	4	33	8	42	.244	.315	.422	.737
11	Athletics	36	92	.543	50	42	3,147	434	793	175	8	135	419	275	29	829	42	20	3,486	1,389	318	14	21	9	53	.252	.316	.441	.757
12	Royals	35	93	.516	48	45	3,107	420	758	181	9	113	411	272	47	621	58	19	3,459	1,296	303	14	19	9	60	.244	.313	.417	.730
13	Diamondbacks	10	94	.489	46	48	3,175	445	789	151	24	116	429	294	51	799	68	24	3,584	1,336	291	25	39	12	60	.249	.319	.421	.739
14	Guardians	8	95	.558	53	42	3,125	378	687	150	12	99	370	281	33	797	75	18	3,484	1,158	261	19	26	20	37	.220	.289	.371	.659
15	Marlins	4	96	.563	54	42	3,293	445	831	161	21	97	423	285	38	709	85	21	3,650	1,325	279	5	29	8	55	.252	.317	.402	.719
16	Reds	2	93	.516	48	45	3,137	405	767	136	16	92	378	287	29	807	46	9	3,488	1,211	244	6	29	8	65	.245	.311	.386	.697
17	Pirates	-9	92	.467	43	49	3,068	356	718	157	8	68	344	294	26	809	50	17	3,415	1,095	233	8	19	9	61	.234	.305	.357	.662
18	Astros	-9	94	.521	49	45	3,225	409	796	148	6	115	391	278	42	784	44	15	3,573	1,301	269	8	20	9	67	.247	.313	.403	.716
19	Rays	-16	94	.436	41	53	3,199	413	817	135	13	111	394	263	25	822	98	29	3,522	1,311	259	12	23	7	66	.255	.315	.410	.725
20	Braves	-20	95	.495	47	48	3,230	451	794	149	13	117	438	345	29	791	46	13	3,636	1,320	279	8	24	7	57	.246	.322	.409	.731
21	Tigers	-21	92	.457	42	50	3,086	423	753	137	23	119	403	288	38	832	36	10	3,446	1,293	279	1	33	6	49	.244	.313	.419	.732
22	Orioles	-26	95	.505	48	47	3,183	417	740	153	10	117	401	293	46	866	71	24	3,544	1,264	280	2	20	11	49	.232	.305	.397	.702
23	Giants	-27	93	.441	41	52	3,109	411	733	137	17	108	392	312	43	796	26	9	3,504	1,228	262	10	30	9	58	.236	.311	.395	.706
24	White Sox	-37	93	.398	37	56	3,131	405	750	137	6	111	394	269	35	772	36	7	3,465	1,232	254	12	18	6	69	.240	.305	.393	.699
25	Mets	-44	93	.409	38	55	3,155	447	787	145	6	135	436	310	41	797	89	9	3,547	1,349	286	12	29	14	59	.249	.322	.428	.749