The New York Yankees have the highest run differential by a team this season, with a differential of 90 runs.

Interpreted as:

best run differntial this regular season

	TEAM	DIFF	SEASON	G	W%	W	L	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	AVG	OBP	SLG	OPS
1	Yankees	90	2025	46	.587	27	19	1,574	266	411	87	6	79	255	192	25	412	33	10	1,810	747	172	1	18	10	26	.261	.347	.475	.822
2	Tigers	87	2025	47	.660	31	16	1,605	253	418	69	7	60	241	161	20	411	20	3	1,803	681	136	4	13	4	30	.260	.333	.424	.757
3	Cubs	70	2025	47	.596	28	19	1,629	270	414	84	13	65	264	182	14	374	59	10	1,846	719	162	5	16	5	20	.254	.331	.441	.773
4	Dodgers	63	2025	47	.617	29	18	1,606	272	436	80	9	77	261	180	15	391	33	9	1,820	765	166	3	16	7	36	.271	.347	.476	.824
5	Mets	56	2025	47	.617	29	18	1,558	212	385	83	11	52	203	172	26	359	34	5	1,775	646	146	2	17	6	40	.247	.329	.415	.743
6	Giants	47	2025	47	.596	28	19	1,559	222	369	75	6	50	212	165	12	404	25	11	1,756	606	131	8	12	4	24	.237	.312	.389	.701
7	Cardinals	38	2025	47	.553	26	21	1,607	224	421	91	1	45	211	161	21	359	31	10	1,808	649	137	5	14	8	38	.262	.334	.404	.738
8	Padres	38	2025	45	.600	27	18	1,496	199	391	66	6	41	181	144	12	308	36	9	1,676	592	113	10	14	5	31	.261	.328	.396	.724
9	Twins	35	2025	47	.553	26	21	1,569	194	380	78	6	45	185	132	27	385	26	9	1,738	605	129	0	10	3	28	.242	.310	.386	.696
10	Reds	30	2025	48	.500	24	24	1,611	220	391	80	3	53	212	169	18	434	52	14	1,809	636	136	3	8	4	27	.243	.320	.395	.715
11	Phillies	24	2025	46	.609	28	18	1,561	216	400	70	7	46	206	175	14	365	41	8	1,764	622	123	4	10	6	31	.256	.335	.398	.733
12	Mariners	23	2025	45	.578	26	19	1,523	216	363	59	2	62	208	179	24	404	45	13	1,745	612	123	8	11	3	26	.238	.326	.402	.728
13	Astros	20	2025	46	.522	24	22	1,520	185	372	66	5	39	176	150	17	355	22	9	1,706	565	110	8	11	5	34	.245	.317	.372	.689
14	Braves	11	2025	47	.511	24	23	1,596	195	394	66	6	50	187	161	14	397	31	9	1,786	622	122	5	10	4	28	.247	.319	.390	.709
15	Red Sox	8	2025	48	.479	23	25	1,672	234	425	88	7	60	224	161	20	437	49	12	1,866	707	155	3	10	10	21	.254	.325	.423	.748
16	Diamondbacks	3	2025	47	.532	25	22	1,586	243	405	98	8	64	236	184	22	351	43	11	1,820	711	170	8	20	6	34	.255	.337	.448	.785
17	Rangers	1	2025	48	.521	25	23	1,548	166	352	59	4	50	163	123	16	373	41	10	1,702	569	113	2	13	2	26	.227	.289	.368	.656
18	Royals	-1	2025	48	.542	26	22	1,600	159	385	80	11	30	157	121	15	332	40	15	1,760	577	121	9	15	8	22	.241	.298	.361	.658
19	Brewers	-7	2025	47	.468	22	25	1,544	198	352	59	4	37	179	157	20	386	59	14	1,743	530	100	11	11	6	24	.228	.305	.343	.649
20	Rays	-9	2025	46	.457	21	25	1,541	179	373	63	3	39	171	139	10	393	57	12	1,705	559	105	0	15	0	33	.242	.306	.363	.669
21	Guardians	-20	2025	46	.543	25	21	1,488	182	346	60	3	51	171	149	18	360	36	12	1,680	565	114	7	18	6	26	.233	.307	.380	.686
22	Blue Jays	-28	2025	46	.478	22	24	1,546	179	385	80	1	40	173	147	16	343	29	9	1,733	587	121	9	15	8	34	.249	.318	.380	.698
23	Nationals	-49	2025	48	.438	21	27	1,594	207	384	73	7	50	196	142	22	387	49	15	1,778	621	130	9	11	1	27	.241	.310	.390	.699
24	White Sox	-53	2025	47	.298	14	33	1,522	157	330	61	1	37	152	146	11	397	37	7	1,694	504	99	5	10	1	27	.217	.288	.331	.619
25	Angels	-59	2025	45	.444	20	25	1,485	181	326	60	5	65	175	115	18	440	19	7	1,631	591	130	3	10	5	28	.220	.282	.398	.680