The Chicago White Sox have the highest run differential by a team in a game this season, with a differential of 21 runs versus the Royals on June 26.
Interpreted as:
biggest win margin in one regular-season game in MLB history in 2026| TEAM | DIFF | DATE | TM | OPP | RESULT | AB | R | H | 2B | 3B | HR | RBI | BB | HBP | SO | SB | CS | PA | TB | XBH | SH | SF | IBB | GIDP | AVG | OBP | SLG | OPS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | White Sox | 21 | 6/26/2026 | vs | W 22-1 | 46 | 22 | 23 | 3 | 0 | 5 | 22 | 7 | 0 | 9 | 0 | 0 | 53 | 41 | 8 | 0 | 0 | 0 | 2 | .500 | .566 | .891 | 1.457 | ||
| 2 |  | Cubs | 20 | 7/1/2026 | vs | W 23-3 | 42 | 23 | 17 | 2 | 0 | 8 | 23 | 7 | 0 | 10 | 1 | 0 | 49 | 43 | 10 | 0 | 0 | 1 | 0 | .405 | .490 | 1.024 | 1.514 | ||
| 3 |  | Nationals | 19 | 7/17/2026 | @ | W 23-4 | 48 | 23 | 21 | 6 | 0 | 4 | 23 | 6 | 0 | 13 | 2 | 0 | 54 | 39 | 10 | 0 | 0 | 0 | 0 | .438 | .500 | .813 | 1.313 | ||
| 4 |  | Padres | 17 | 7/19/2026 | @ | W 19-2 | 46 | 19 | 19 | 3 | 0 | 5 | 19 | 6 | 2 | 4 | 2 | 0 | 55 | 37 | 8 | 0 | 1 | 0 | 0 | .413 | .491 | .804 | 1.295 | ||
| 5 |  | Cardinals | 16 | 7/3/2026 | @ | W 17-1 | 43 | 17 | 17 | 3 | 0 | 3 | 17 | 4 | 3 | 7 | 0 | 0 | 51 | 29 | 6 | 0 | 1 | 0 | 0 | .395 | .471 | .674 | 1.145 | ||
| 6 |  | Red Sox | 16 | 4/25/2026 | @ | W 17-1 | 44 | 17 | 17 | 4 | 1 | 3 | 17 | 5 | 0 | 7 | 2 | 1 | 50 | 32 | 8 | 0 | 1 | 0 | 0 | .386 | .440 | .727 | 1.167 | ||
| 7 |  | Giants | 15 | 6/5/2026 | @ | W 18-3 | 44 | 18 | 19 | 3 | 0 | 7 | 18 | 2 | 1 | 9 | 0 | 0 | 49 | 43 | 10 | 0 | 2 | 0 | 0 | .432 | .449 | .977 | 1.426 | ||
| 8 |  | Braves | 15 | 4/2/2026 | @ | W 17-2 | 43 | 17 | 16 | 5 | 0 | 4 | 17 | 8 | 0 | 6 | 0 | 0 | 52 | 33 | 9 | 0 | 1 | 0 | 0 | .372 | .462 | .767 | 1.229 | ||
| 9 |  | Tigers | 14 | 7/28/2026 | vs | W 14-0 | 41 | 14 | 19 | 3 | 1 | 3 | 14 | 4 | 0 | 7 | 0 | 0 | 46 | 33 | 7 | 0 | 1 | 0 | 1 | .463 | .500 | .805 | 1.305 | ||
| 10 |  | Athletics | 14 | 7/18/2026 | vs | W 15-1 | 36 | 15 | 13 | 3 | 0 | 3 | 15 | 7 | 3 | 6 | 0 | 0 | 46 | 25 | 6 | 0 | 0 | 0 | 1 | .361 | .500 | .694 | 1.194 | ||
| 11 | | Braves | 14 | 7/17/2026 | vs | W 15-1 | 42 | 15 | 19 | 5 | 0 | 3 | 15 | 6 | 1 | 5 | 0 | 0 | 49 | 33 | 8 | 0 | 0 | 0 | 1 | .452 | .531 | .786 | 1.316 | ||
| 12 |  | Royals | 14 | 7/6/2026 | vs | W 15-1 | 44 | 15 | 22 | 2 | 0 | 4 | 14 | 5 | 1 | 5 | 0 | 1 | 50 | 36 | 6 | 0 | 0 | 0 | 0 | .500 | .560 | .818 | 1.378 | ||
| 13 | | Cubs | 14 | 6/19/2026 | vs | W 16-2 | 44 | 16 | 18 | 2 | 1 | 1 | 16 | 11 | 0 | 4 | 4 | 0 | 55 | 25 | 4 | 0 | 0 | 0 | 0 | .409 | .527 | .568 | 1.095 | ||
| 14 |  | Rockies | 14 | 6/14/2026 | @ | W 23-9 | 50 | 23 | 24 | 5 | 2 | 6 | 23 | 5 | 0 | 7 | 0 | 0 | 56 | 51 | 13 | 0 | 1 | 0 | 1 | .480 | .518 | 1.020 | 1.538 | ||
| 15 |  | Brewers | 14 | 6/1/2026 | vs | W 16-2 | 38 | 16 | 18 | 6 | 1 | 0 | 15 | 11 | 0 | 6 | 0 | 0 | 51 | 26 | 7 | 0 | 2 | 0 | 2 | .474 | .569 | .684 | 1.253 | ||
| 16 |  | Yankees | 14 | 5/26/2026 | @ | W 15-1 | 50 | 15 | 24 | 4 | 0 | 6 | 15 | 5 | 0 | 5 | 0 | 0 | 55 | 46 | 10 | 0 | 0 | 0 | 0 | .480 | .527 | .920 | 1.447 | ||
| 17 |  | Reds | 14 | 5/14/2026 | vs | W 15-1 | 37 | 15 | 14 | 3 | 0 | 4 | 15 | 4 | 1 | 9 | 0 | 0 | 42 | 29 | 7 | 0 | 0 | 0 | 1 | .378 | .452 | .784 | 1.236 | ||
| 18 | | Giants | 13 | 7/29/2026 | vs | W 16-3 | 42 | 16 | 17 | 1 | 0 | 2 | 15 | 7 | 1 | 5 | 3 | 1 | 50 | 24 | 3 | 0 | 0 | 0 | 0 | .405 | .500 | .571 | 1.071 | ||
| 19 | | White Sox | 13 | 7/10/2026 | vs | W 14-1 | 38 | 14 | 15 | 7 | 1 | 2 | 14 | 4 | 0 | 9 | 1 | 0 | 43 | 30 | 10 | 0 | 1 | 0 | 0 | .395 | .442 | .789 | 1.231 | ||
| 20 | | Nationals | 13 | 6/5/2026 | @ | W 14-1 | 43 | 14 | 16 | 1 | 0 | 5 | 14 | 7 | 2 | 7 | 1 | 0 | 52 | 32 | 6 | 0 | 0 | 0 | 0 | .372 | .481 | .744 | 1.225 | ||
| 21 | | Giants | 13 | 5/31/2026 | @ | W 19-6 | 50 | 19 | 25 | 9 | 1 | 3 | 18 | 4 | 1 | 9 | 1 | 0 | 57 | 45 | 13 | 0 | 2 | 1 | 0 | .500 | .526 | .900 | 1.426 | ||
| 22 | | White Sox | 13 | 5/27/2026 | vs | W 15-2 | 37 | 15 | 18 | 1 | 0 | 2 | 13 | 7 | 0 | 8 | 2 | 0 | 46 | 25 | 3 | 1 | 1 | 0 | 2 | .486 | .556 | .676 | 1.231 | ||
| 23 |  | Dodgers | 13 | 5/16/2026 | @ | W 15-2 | 36 | 15 | 10 | 1 | 1 | 1 | 13 | 9 | 2 | 9 | 1 | 0 | 48 | 16 | 3 | 0 | 1 | 0 | 1 | .278 | .438 | .444 | .882 | ||
| 24 |  | Blue Jays | 13 | 5/9/2026 | vs | W 14-1 | 44 | 14 | 20 | 2 | 0 | 3 | 13 | 3 | 1 | 2 | 0 | 0 | 49 | 31 | 5 | 0 | 1 | 0 | 0 | .455 | .490 | .705 | 1.194 | ||
| 25 | | Nationals | 13 | 5/6/2026 | vs | W 15-2 | 38 | 15 | 14 | 5 | 1 | 4 | 15 | 5 | 0 | 7 | 3 | 0 | 43 | 33 | 10 | 0 | 0 | 0 | 0 | .368 | .442 | .868 | 1.310 | ||
CWS
KCR
CHC
SDP
WSH
ATH
STL
BOS
BAL
SFG
ATL
AZ
DET
TEX
PHI
TOR
COL
MIL
NYY
CIN
MIN
LAD
LAASome of the information used here was obtained free of charge from Retrosheet.
More MLB News
Payton Tolle pitches 8-inning gem as Red Sox end 5-game skid with 7-0 win over Blue Jays
Washington Nationals pitcher Cade Cavalli's no-hit bid ends after 6 2/3 innings against Cubs
Logan Gilbert pitches 6 strong innings as Mariners stop 6-game skid with 1-0 win over Yankees
Ashcraft throws complete game, Flores has 2 homers, 6 RBIs as Pirates rout Marlins 13-1
Utility player Jorge Mateo signs major-league contract with Rays after Braves release him
Sal Stewart homers as Reds hold off Chicago White Sox for a 9-8 win
More White Sox Stats
Team Batting Leaders 
HR
26
Murakami
RBI
68
Vargas
AVG
.280
Antonacci
Team Pitching Leaders 
W
9
Martin
K
152
Burke
ERA
2.20
Taylor
Team Rankings
HR
157
6th
R
574
8th
SO
1,017
16th
ERA
4.10
14th
Guardians
MLB 2026 Batting Leaders
MLB 2026 Pitching Leaders
MLB Fantasy 2026
MLB 2026 Betting
MLB 2026 Standings
| AL East | W | L | PCT | GB |
|---|---|---|---|---|
74 | 46 | .617 | ||
68 | 53 | .562 | 6.5 | |
65 | 56 | .537 | 9.5 | |
59 | 64 | .480 | 16.5 | |
58 | 63 | .479 | 16.5 | |
| AL Central | W | L | PCT | GB |
62 | 58 | .517 | ||
60 | 61 | .496 | 2.5 | |
60 | 62 | .492 | 3.0 | |
59 | 63 | .484 | 4.0 | |
49 | 73 | .402 | 14.0 | |
| AL West | W | L | PCT | GB |
62 | 60 | .508 | ||
60 | 61 | .496 | 1.5 | |
57 | 65 | .467 | 5.0 | |
47 | 74 | .388 | 14.5 | |
47 | 74 | .388 | 14.5 |
Rays
Astros
Mariners| NL East | W | L | PCT | GB |
|---|---|---|---|---|
73 | 48 | .603 | ||
64 | 58 | .525 | 9.5 | |
62 | 60 | .508 | 11.5 | |
60 | 63 | .488 | 14.0 | |
53 | 69 | .434 | 20.5 | |
| NL Central | W | L | PCT | GB |
74 | 47 | .612 | ||
71 | 51 | .582 | 3.5 | |
61 | 60 | .504 | 13.0 | |
58 | 62 | .483 | 15.5 | |
59 | 64 | .480 | 16.0 | |
| NL West | W | L | PCT | GB |
73 | 48 | .603 | ||
65 | 57 | .533 | 8.5 | |
64 | 58 | .525 | 9.5 | |
50 | 71 | .413 | 23.0 | |
48 | 73 | .397 | 25.0 |
Marlins
Mets
Pirates