| TEAM | R | SEASON | G | W% | W | L | GS | ERA | SO | CG | SHO | SV | IP | H | ER | HR | BB | HBP | IBB | TBF | WP | K/9 | BB/9 | K/BB | HR/9 | K% | BB% | WHIP | BABIP | RA | H/9 | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cubs | 240 | 2020 | 60 | .567 | 34 | 26 | 60 | 3.99 | 523 | 2 | 2 | 16 | 518.1 | 451 | 230 | 74 | 182 | 17 | 7 | 2,153 | 22 | 9.08 | 3.16 | 2.87 | 1.28 | 24.3 | 8.5 | 1.22 | .278 | 4.17 | 7.83 |
| 2 | | Cubs | 839 | 2021 | 162 | .438 | 71 | 91 | 162 | 4.87 | 1,358 | 1 | 0 | 40 | 1412.2 | 1,386 | 765 | 235 | 596 | 98 | 25 | 6,202 | 60 | 8.65 | 3.80 | 2.28 | 1.50 | 21.9 | 9.6 | 1.40 | .294 | 5.35 | 8.83 |
| 3 | | Cubs | 731 | 2022 | 162 | .457 | 74 | 88 | 162 | 4.00 | 1,383 | 0 | 0 | 44 | 1443.2 | 1,342 | 642 | 207 | 540 | 73 | 19 | 6,162 | 53 | 8.62 | 3.37 | 2.56 | 1.29 | 22.4 | 8.8 | 1.30 | .287 | 4.56 | 8.37 |
| 4 | | Cubs | 723 | 2023 | 162 | .512 | 83 | 79 | 162 | 4.08 | 1,377 | 1 | 1 | 35 | 1435.1 | 1,328 | 651 | 179 | 513 | 64 | 5 | 6,085 | 57 | 8.63 | 3.22 | 2.68 | 1.12 | 22.6 | 8.4 | 1.28 | .291 | 4.53 | 8.33 |
| 5 | | Cubs | 669 | 2024 | 162 | .512 | 83 | 79 | 162 | 3.78 | 1,348 | 1 | 0 | 38 | 1432.1 | 1,302 | 602 | 181 | 485 | 48 | 7 | 6,032 | 40 | 8.47 | 3.05 | 2.78 | 1.14 | 22.3 | 8.0 | 1.25 | .282 | 4.20 | 8.18 |
| 6 | | Cubs | 649 | 2025 | 162 | .568 | 92 | 70 | 162 | 3.79 | 1,265 | 0 | 0 | 44 | 1435.0 | 1,284 | 605 | 202 | 405 | 53 | 9 | 5,904 | 29 | 7.93 | 2.54 | 3.12 | 1.27 | 21.4 | 6.9 | 1.18 | .272 | 4.07 | 8.05 |
| Total | 3,851 | 870 | .502 | 437 | 433 | 870 | 4.10 | 7,254 | 5 | 3 | 217 | 7677.1 | 7,093 | 3,495 | 1,078 | 2,721 | 353 | 72 | 32,538 | 261 | 8.50 | 3.19 | 2.67 | 1.26 | 22.3 | 8.4 | 1.28 | .285 | 4.51 | 8.31 |
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