Dylan Cease struck out the most hitters for the White Sox in 2022, with 227 strikeouts.

	NAME	SO	SEASON	TM	G	W	L	W%	GS	ERA	CG	SHO	SV	IP	H	ER	R	HR	BB	HBP	GF	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	ERA-	FIP	FIP-	H/9	PRAA
1	Dylan Cease D. Cease	227	2022	CWS	32	14	8	.636	32	2.20	1	1	0	184.0	126	45	55	16	78	3	0	2	747	7	11.10	3.82	2.91	0.78	30.4	10.4	1.11	.260	2.69	56	3.09	75	6.16	20.1
2	Lucas Giolito L. Giolito	177	2022	CWS	30	11	9	.550	30	4.90	0	0	0	161.2	171	88	92	24	61	4	0	1	698	3	9.85	3.40	2.90	1.34	25.4	8.7	1.44	.340	5.12	125	4.05	99	9.52	1
3	Lance Lynn L. Lynn	124	2022	CWS	21	8	7	.533	21	3.99	0	0	0	121.2	119	54	65	19	19	10	0	0	512	4	9.17	1.41	6.53	1.41	24.2	3.7	1.13	.294	4.81	102	3.81	93	8.80	3.9
4	Michael Kopech M. Kopech	105	2022	CWS	25	5	9	.357	25	3.54	0	0	0	119.1	85	47	53	15	57	3	0	0	494	2	7.92	4.30	1.84	1.13	21.3	11.5	1.19	.223	4.00	91	4.49	110	6.41	-4.8
5	Johnny Cueto J. Cueto	102	2022	CWS	25	8	10	.444	24	3.35	1	0	0	158.1	161	59	66	15	33	6	0	2	651	2	5.80	1.88	3.09	0.85	15.7	5.1	1.23	.295	3.75	86	3.79	92	9.15	5.5
6	Liam Hendriks L. Hendriks	85	2022	CWS	58	4	4	.500	0	2.81	0	0	37	57.2	44	18	22	7	16	2	51	1	235	8	13.27	2.50	5.31	1.09	36.2	6.8	1.04	.296	3.43	72	2.67	65	6.87	8.9
7	Vince Velasquez V. Velasquez	69	2022	CWS	27	3	3	.500	9	4.78	0	0	0	75.1	68	40	42	11	25	2	8	0	319	1	8.24	2.99	2.76	1.31	21.6	7.8	1.23	.269	5.02	122	4.25	104	8.12	-1.1
8	José Ruiz J. Ruiz	68	2022	CWS	63	1	0	1.000	0	4.60	0	0	0	60.2	53	31	32	9	33	0	21	0	265	4	10.09	4.90	2.06	1.34	25.7	12.5	1.42	.284	4.75	117	4.42	108	7.86	-2
9	Kendall Graveman K. Graveman	66	2022	CWS	65	3	4	.429	0	3.18	0	0	6	65.0	65	23	29	5	26	3	14	2	285	3	9.14	3.60	2.54	0.69	23.2	9.1	1.40	.324	4.02	81	3.41	83	9.00	4.8
10	Reynaldo López R. López	63	2022	CWS	61	6	4	.600	1	2.76	0	0	0	65.1	51	20	24	1	11	1	8	1	254	4	8.68	1.52	5.73	0.14	24.8	4.3	0.95	.281	3.31	70	1.93	47	7.03	15.2
11	Joe Kelly J. Kelly	53	2022	CWS	43	1	3	.250	1	6.08	0	0	1	37.0	36	25	26	2	23	3	4	0	170	4	12.89	5.59	2.30	0.49	31.2	13.5	1.59	.382	6.32	155	3.05	75	8.76	4.2
12	Tanner Banks T. Banks	49	2022	CWS	35	2	0	1.000	0	3.06	0	0	0	53.0	42	18	25	5	18	1	15	0	217	2	8.32	3.06	2.72	0.85	22.6	8.3	1.13	.257	4.25	78	3.56	87	7.13	3.1
13	Davis Martin D. Martin	48	2022	CWS	14	3	6	.333	9	4.83	0	0	0	63.1	63	34	36	8	19	3	1	1	269	3	6.82	2.70	2.53	1.14	17.8	7.1	1.29	.288	5.12	123	4.27	104	8.95	-1.1
14	Jimmy Lambert J. Lambert	45	2022	CWS	42	1	2	.333	2	3.26	0	0	0	47.0	40	17	18	4	24	1	7	0	204	5	8.62	4.60	1.88	0.77	22.1	11.8	1.36	.277	3.45	83	3.89	95	7.66	1.1
15	Matt Foster M. Foster	42	2022	CWS	48	1	2	.333	0	4.40	0	0	1	45.0	43	22	25	6	17	0	12	1	193	1	8.40	3.40	2.47	1.20	21.8	8.8	1.33	.289	5.00	112	4.11	100	8.60	0
16	Aaron Bummer A. Bummer	30	2022	CWS	32	2	1	.667	0	2.36	0	0	2	26.2	30	7	11	2	10	2	3	0	117	0	10.13	3.38	3.00	0.68	25.6	8.5	1.50	.384	3.71	60	3.18	78	10.13	2.6
17	Jake Diekman J. Diekman	28	2022	CWS	26	0	3	.000	0	6.52	0	0	0	19.1	25	14	18	4	12	2	2	1	98	2	13.03	5.59	2.33	1.86	28.6	12.2	1.91	.404	8.38	166	5.07	124	11.64	-2
18	Dallas Keuchel D. Keuchel	20	2022	CWS	8	2	5	.286	8	7.88	0	0	0	32.0	49	28	33	6	20	0	0	2	164	3	5.63	5.63	1.00	1.69	12.2	12.2	2.16	.364	9.28	201	6.17	151	13.78	-7
19	Kyle Crick K. Crick	19	2022	CWS	14	2	0	1.000	0	4.02	0	0	0	15.2	10	7	7	0	11	2	3	0	66	0	10.91	6.32	1.73	0.00	28.8	16.7	1.34	.294	4.02	103	3.17	77	5.74	1.6
20	Bennett Sousa B. Sousa	12	2022	CWS	25	3	0	1.000	0	8.41	0	0	1	20.1	25	19	20	3	10	1	2	1	96	4	5.31	4.43	1.20	1.33	12.5	10.4	1.72	.314	8.85	215	5.47	133	11.07	-2.9
21	Anderson Severino A. Severino	9	2022	CWS	6	0	0		0	6.14	0	0	0	7.1	7	5	5	0	4	2	4	0	34	2	11.05	4.91	2.25	0.00	26.5	11.8	1.50	.368	6.14	157	3.11	76	8.59	0.8
22	Ryan Burr R. Burr	7	2022	CWS	8	1	1	.500	0	6.00	0	0	0	9.0	8	6	7	3	4	0	2	0	39	0	7.00	4.00	1.75	3.00	17.9	10.3	1.33	.200	7.00	153	7.22	176	8.00	-3
23	Josh Harrison J. Harrison	2	2022	CWS	3	0	0		0	18.00	0	0	0	3.0	9	6	6	1	2	0	3	0	18	0	6.00	6.00	1.00	3.00	11.1	11.1	3.67	.615	18.00	460	8.11	198	27.00	-1.3