Gerrit Cole has a 12-4 record with an ERA of 2.43 and 132 strikeouts in 18 appearances against the Cubs in his career.
| NAME | DATE | TM | OPP | DEC | GS | ERA | SO | CG | SHO | SV | IP | H | ER | R | HR | BB | HBP | GF | IBB | TBF | WP | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | G. Cole | 9/14/2013 | vs | W | 1 | 1.29 | 7 | 0 | 0 | 0 | 7.0 | 5 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 28 | 0 | ||
| 2 | | G. Cole | 9/24/2013 | @ | W | 1 | 3.00 | 6 | 0 | 0 | 0 | 6.0 | 7 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 24 | 0 | ||
| 3 | | G. Cole | 4/10/2014 | @ | W | 1 | 4.50 | 10 | 0 | 0 | 0 | 6.0 | 5 | 3 | 4 | 0 | 2 | 1 | 0 | 0 | 25 | 1 | ||
| 4 | | G. Cole | 9/7/2014 | @ | W | 1 | 4.50 | 8 | 0 | 0 | 0 | 6.0 | 9 | 3 | 4 | 0 | 0 | 1 | 0 | 0 | 27 | 1 | ||
| 5 | | G. Cole | 9/12/2014 | vs | W | 1 | 4.50 | 6 | 0 | 0 | 0 | 6.0 | 5 | 3 | 3 | 2 | 1 | 1 | 0 | 0 | 25 | 0 | ||
| 6 | | G. Cole | 4/21/2015 | vs | ||||||||||||||||||||
| 7 | | G. Cole | 4/29/2015 | @ | W | 1 | 0.00 | 8 | 0 | 0 | 0 | 6.0 | 3 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 20 | 0 | ||
| 8 | | G. Cole | 5/16/2015 | @ | L | 1 | 3.00 | 8 | 0 | 0 | 0 | 6.0 | 7 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 25 | 0 | ||
| 9 | | G. Cole | 9/15/2015 | vs | 1 | 4.26 | 8 | 0 | 0 | 0 | 6.1 | 6 | 3 | 4 | 0 | 0 | 1 | 0 | 0 | 26 | 0 | |||
| 10 | | G. Cole | 9/25/2015 | @ | W | 1 | 1.29 | 8 | 0 | 0 | 0 | 7.0 | 4 | 1 | 1 | 0 | 2 | 0 | 0 | 0 | 26 | 0 | ||
| 11 | | G. Cole | 5/2/2016 | vs | L | 1 | 9.64 | 6 | 0 | 0 | 0 | 4.2 | 6 | 5 | 6 | 0 | 4 | 1 | 0 | 0 | 25 | 0 | ||
| 12 | | G. Cole | 5/15/2016 | @ | W | 1 | 0.00 | 7 | 0 | 0 | 0 | 8.0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27 | 0 | ||
| 13 | | G. Cole | 4/14/2017 | @ | W | 1 | 3.00 | 5 | 0 | 0 | 0 | 6.0 | 6 | 2 | 2 | 0 | 1 | 0 | 0 | 0 | 25 | 0 | ||
| 14 | | G. Cole | 4/25/2017 | vs | L | 1 | 0.00 | 8 | 0 | 0 | 0 | 7.0 | 2 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 24 | 0 | ||
| 15 | | G. Cole | 9/6/2017 | vs | 1 | 0.00 | 8 | 0 | 0 | 0 | 8.0 | 2 | 0 | 0 | 0 | 4 | 0 | 0 | 0 | 29 | 0 | |||
| 16 |  | G. Cole | 5/27/2019 | vs | W | 1 | 3.00 | 12 | 0 | 0 | 0 | 6.0 | 3 | 2 | 2 | 1 | 1 | 0 | 0 | 0 | 22 | 0 | ||
| 17 |  | G. Cole | 7/8/2023 | vs | W | 1 | 3.68 | 5 | 0 | 0 | 0 | 7.1 | 5 | 3 | 3 | 1 | 1 | 0 | 0 | 0 | 28 | 1 | ||
| 18 | | G. Cole | 9/8/2024 | @ | L | 1 | 0.00 | 7 | 0 | 0 | 0 | 6.0 | 3 | 0 | 2 | 0 | 1 | 0 | 0 | 0 | 23 | 0 | ||
| 19 | | G. Cole | 8/2/2026 | @ | W | 1 | 1.59 | 5 | 0 | 0 | 0 | 5.2 | 4 | 1 | 1 | 0 | 3 | 0 | 0 | 0 | 23 | 0 | ||
| Total | 18 | 2.43 | 132 | 0 | 0 | 0 | 115.0 | 85 | 31 | 39 | 4 | 26 | 6 | 0 | 0 | 452 | 3 |
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