The Colorado Rockies have given up the most runs by a team this season, with 425 runs.

Interpreted as:

given up the most runs team this regular season

	TEAM	R	SEASON	G	W%	W	L	GS	ERA	SO	CG	SHO	SV	IP	H	ER	HR	BB	HBP	IBB	TBF	WP	K/9	BB/9	K/BB	HR/9	K%	BB%	WHIP	BABIP	RA	H/9
1	Rockies	425	2025	68	.191	13	55	68	5.63	457	0	0	10	591.1	695	370	88	242	22	8	2,669	32	6.96	3.68	1.89	1.34	17.1	9.1	1.58	.326	6.47	10.58
2	Athletics	419	2025	70	.371	26	44	70	5.63	559	0	0	15	620.0	670	388	104	273	38	10	2,803	15	8.11	3.96	2.05	1.51	19.9	9.7	1.52	.309	6.08	9.73
3	Marlins	357	2025	66	.379	25	41	66	5.06	523	0	0	12	585.0	596	329	81	235	25	8	2,563	20	8.05	3.62	2.23	1.25	20.4	9.2	1.42	.303	5.49	9.17
4	Diamondbacks	350	2025	68	.500	34	34	68	4.77	577	0	0	22	607.0	585	322	89	232	30	10	2,621	14	8.56	3.44	2.49	1.32	22.0	8.9	1.35	.293	5.19	8.67
5	Orioles	345	2025	67	.403	27	40	67	5.00	541	0	0	15	586.1	614	326	94	219	20	3	2,557	25	8.30	3.36	2.47	1.44	21.2	8.6	1.42	.309	5.30	9.42
6	Nationals	340	2025	68	.441	30	38	68	4.88	535	0	0	19	597.0	590	324	69	231	45	1	2,607	33	8.07	3.48	2.32	1.04	20.5	8.9	1.38	.302	5.13	8.89
7	Angels	335	2025	67	.493	33	34	67	4.76	501	0	0	18	590.1	611	312	86	270	22	18	2,601	28	7.64	4.12	1.86	1.31	19.3	10.4	1.49	.305	5.11	9.32
8	Red Sox	327	2025	70	.486	34	36	70	4.08	587	0	0	17	630.1	611	286	70	234	32	10	2,708	15	8.38	3.34	2.51	1.00	21.7	8.6	1.34	.303	4.67	8.72
9	Dodgers	313	2025	69	.594	41	28	69	4.16	614	0	0	21	616.0	564	285	86	247	29	13	2,624	31	8.97	3.61	2.49	1.26	23.4	9.4	1.32	.290	4.57	8.24
10	Mariners	305	2025	67	.493	33	34	67	4.06	544	0	0	19	607.0	600	274	78	209	26	14	2,599	20	8.07	3.10	2.60	1.16	20.9	8.0	1.33	.300	4.52	8.90
11	White Sox	300	2025	69	.333	23	46	69	4.19	501	0	0	7	594.2	577	277	74	248	41	10	2,590	16	7.58	3.75	2.02	1.12	19.3	9.6	1.39	.291	4.54	8.73
12	Cardinals	299	2025	69	.522	36	33	69	3.98	484	1	1	17	612.2	599	271	57	187	21	8	2,591	19	7.11	2.75	2.59	0.84	18.7	7.2	1.28	.294	4.39	8.80
13	Phillies	295	2025	68	.574	39	29	68	4.00	638	0	0	20	610.0	588	271	72	208	19	6	2,592	19	9.41	3.07	3.07	1.06	24.6	8.0	1.30	.312	4.35	8.68
14	Blue Jays	292	2025	68	.559	38	30	68	4.06	610	0	0	23	607.2	539	274	95	202	30	7	2,534	16	9.03	2.99	3.02	1.41	24.1	8.0	1.22	.278	4.32	7.98
15	Brewers	283	2025	70	.529	37	33	70	3.80	576	0	0	17	620.1	555	262	73	253	23	12	2,637	16	8.36	3.67	2.28	1.06	21.8	9.6	1.30	.282	4.11	8.05
16	Pirates	280	2025	70	.400	28	42	70	3.78	521	1	0	15	621.0	535	261	58	208	25	10	2,574	19	7.55	3.01	2.50	0.84	20.2	8.1	1.20	.271	4.06	7.75
17	Guardians	279	2025	67	.522	35	32	67	3.89	569	0	0	19	591.2	564	256	73	242	19	7	2,532	21	8.66	3.68	2.35	1.11	22.5	9.6	1.36	.301	4.24	8.58
18	Reds	278	2025	69	.507	35	34	69	3.77	553	1	1	19	611.0	522	256	78	206	27	5	2,540	21	8.15	3.03	2.68	1.15	21.8	8.1	1.19	.265	4.09	7.69
19	Cubs	275	2025	69	.609	42	27	69	3.68	537	0	0	16	616.2	571	252	73	194	23	6	2,569	13	7.84	2.83	2.77	1.07	20.9	7.6	1.24	.286	4.01	8.33
20	Twins	273	2025	68	.529	36	32	68	3.83	591	0	0	14	599.0	548	255	73	179	32	4	2,520	14	8.88	2.69	3.30	1.10	23.5	7.1	1.21	.289	4.10	8.23
21	Braves	263	2025	67	.433	29	38	67	3.73	595	1	0	10	591.1	505	245	75	218	27	10	2,459	19	9.06	3.32	2.73	1.14	24.2	8.9	1.22	.278	4.00	7.69
22	Yankees	259	2025	67	.627	42	25	67	3.67	626	0	0	21	593.0	486	242	68	223	16	2	2,470	20	9.50	3.38	2.81	1.03	25.3	9.0	1.20	.272	3.93	7.38
23	Padres	255	2025	67	.567	38	29	67	3.44	581	2	2	24	596.0	500	228	66	226	26	7	2,494	16	8.77	3.41	2.57	1.00	23.3	9.1	1.22	.272	3.85	7.55
24	Rays	254	2025	68	.529	36	32	68	3.54	543	1	0	16	609.1	534	240	90	178	26	5	2,489	8	8.02	2.63	3.05	1.33	21.8	7.2	1.17	.269	3.75	7.89
25	Royals	252	2025	69	.493	34	35	69	3.40	561	0	0	22	614.2	541	232	67	203	19	9	2,550	29	8.21	2.97	2.76	0.98	22.0	8.0	1.21	.279	3.69	7.92