Babe Ruth has the best batting average with 50+ home runs in a season, with an average of .378 in 1921.

Interpreted as:

highest ba by a player in a 50 or more home run season

	NAME	AVG	HR	SEASON	TM	G	AB	R	H	2B	3B	RBI	BB	HBP	SO	SB	CS	PA	TB	XBH	SH	SF	IBB	GIDP	OBP	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Babe Ruth B. Ruth	.378	59	1921	NYY	152	540	177	204	44	16	168	145	4	81	17	13	693	457	119	4				.512	.846	1.359	214	127.8	.575	224	118.7
2	Babe Ruth B. Ruth	.376	54	1920	NYY	142	458	158	172	36	9	135	150	3	80	14	14	616	388	99	5				.532	.847	1.379	191	120.9	.597	237	110.5
3	Jimmie Foxx J. Foxx	.364	58	1932	PHA	154	585	151	213	33	9	169	116	0	96	3	7	701	438	100	0				.469	.749	1.218	193	105.6	.522	198	95.8
4	Hack Wilson H. Wilson	.356	56	1930	CHC	155	585	146	208	35	6	191	105	1	84	3		709	423	97	18				.454	.723	1.177	189	89	.497	171	78.9
5	Babe Ruth B. Ruth	.356	60	1927	NYY	151	540	158	192	29	8	165	137	0	89	7	6	691	417	97	14				.486	.772	1.258	195	109.9	.545	212	104.8
6	Mickey Mantle M. Mantle	.353	52	1956	NYY	150	533	132	188	22	5	130	112	2	99	10	1	652	376	79	1	4	6	4	.464	.705	1.169	164	88.9	.498	202	84.6
7	Jimmie Foxx J. Foxx	.349	50	1938	BSA	149	565	139	197	33	9	175	119	0	76	5	4	685	398	92	1				.462	.704	1.166	178	91.7	.508	173	74.2
8	Aaron Judge A. Judge	.331	53	2025	NYY	152	541	137	179	30	2	114	124	7	160	12	5	679	372	85	0	7	36	16	.457	.688	1.144	163	82.5	.463	203	82.7
9	Barry Bonds B. Bonds	.328	73	2001	SFG	153	476	129	156	32	2	137	177	9	93	13	3	664	411	107	0	2	35	5	.515	.863	1.379	200	117.7	.537	234	116.6
10	Sammy Sosa S. Sosa	.328	64	2001	CHC	160	577	146	189	34	5	160	116	6	153	0	2	711	425	103	0	12	37	6	.437	.737	1.174	171	82.7	.465	186	79.8
11	Luis Gonzalez L. Gonzalez	.325	57	2001	ARI	162	609	128	198	36	7	142	100	14	83	1	1	728	419	100	0	5	24	14	.429	.688	1.117	168	77.8	.454	173	69.4
12	Babe Ruth B. Ruth	.323	54	1928	NYY	154	536	163	173	29	8	146	137	3	87	4	5	684	380	91	8				.463	.709	1.172	174	90.6	.510	201	89.3
13	Aaron Judge A. Judge	.322	58	2024	NYY	158	559	122	180	36	1	144	133	9	171	10	0	703	392	95	0	2	20	22	.458	.701	1.159	176	93.7	.476	219	95.5
14	George Foster G. Foster	.320	52	1977	CIN	158	615	124	197	31	2	149	61	5	107	6	4	689	388	85	0	8	10	17	.382	.631	1.013	139	58.4	.430	165	54.1
15	Sammy Sosa S. Sosa	.320	50	2000	CHC	156	604	106	193	38	1	138	91	2	168	7	4	705	383	89	0	8	19	12	.406	.634	1.040	146	53.4	.428	154	51.8
16	Willie Mays W. Mays	.319	51	1955	NYG	152	580	123	185	18	13	127	79	4	60	24	4	670	382	82	0	7	13	12	.400	.659	1.059	143	65.3	.450	171	59.7
17	Alex Rodriguez A. Rodriguez	.318	52	2001	TEX	162	632	133	201	34	1	135	75	16	131	18	3	732	393	87	0	9	6	17	.399	.622	1.021	151	60.3	.425	159	54.3
18	Willie Mays W. Mays	.317	52	1965	SFG	157	558	118	177	21	3	112	76	0	71	9	4	638	360	76	2	2	16	11	.398	.645	1.043	136	68.2	.448	186	62.7
19	Mickey Mantle M. Mantle	.317	54	1961	NYY	153	514	131	163	16	6	128	126	0	112	12	1	646	353	76	1	5	9	2	.448	.687	1.135	156	79.6	.478	197	78.8
20	Albert Belle A. Belle	.317	50	1995	CLE	143	546	121	173	52	1	126	73	6	80	5	2	629	377	103	0	4	5	24	.401	.690	1.091	143	64.3	.456	173	59.9
21	Hank Greenberg H. Greenberg	.315	58	1938	DET	155	556	143	175	23	4	147	119	3	92	7	5	681	380	85	3				.438	.683	1.122	166	80.3	.489	162	62
22	Alex Rodriguez A. Rodriguez	.314	54	2007	NYY	158	583	143	183	31	0	156	95	21	120	24	4	708	376	85	0	9	11	15	.422	.645	1.067	155	67.5	.445	175	66.2
23	Ralph Kiner R. Kiner	.313	51	1947	PIT	152	565	118	177	23	4	127	98	2	81	1		666	361	78	1			12	.417	.639	1.055	145	69.5	.472	169	58.2
24	Ryan Howard R. Howard	.313	58	2006	PHI	159	581	104	182	25	1	149	108	9	181	0	0	704	383	84	0	6	37	7	.425	.659	1.084	151	63	.436	162	57.5
25	Mark McGwire M. McGwire	.312	52	1996	OAK	130	423	104	132	21	0	113	116	8	112	0	0	548	309	73	0	1	16	14	.467	.730	1.198	142	71.8	.489	190	68.5