Rogers Hornsby has the highest career on-base percentage by a second baseman, with an on-base percentage of .455.

Interpreted as:

highest career obp with a minimum of 3000 PA for a second baseman

	NAME	OBP	PA	G	AB	R	H	2B	3B	HR	RBI	BB	HBP	SO	SB	CS	TB	XBH	SH	SF	IBB	GIDP	AVG	SLG	OPS	WRC	WRAA	WOBA	WRC+	BRAA
1	Rogers Hornsby R. Hornsby	.455	7,098	1,649	6,060	1,292	2,283	457	117	272	1,295	842	27	478	76		3,790	846	169				.377	.625	1.080	1668	787.3	.484	182	756.9
2	Eddie Collins E. Collins	.425	11,984	2,794	9,902	1,818	3,303	438	186	47	1,298	1,497	77	461	740		4,254	671	508				.334	.430	.855	2028	694.9	.410	144	621.4
3	Max Bishop M. Bishop	.423	5,779	1,338	4,494	966	1,216	236	35	41	379	1,156	31	452	40		1,645	312	98				.271	.366	.789	904	176.3	.383	113	104.4
4	Jackie Robinson J. Robinson	.418	3,241	749	2,743	539	885	165	34	80	453	408	43	155	120	15	1,358	279	47			66	.323	.495	.913	588	207.1	.421	145	181
5	Cupid Childs C. Childs	.416	6,766	1,457	5,622	1,214	1,721	205	101	20	743	991	63	228	269		2,188	326	90				.306	.389	.805	1303	293.6	.396	123	243.3
6	Eddie Stanky E. Stanky	.410	5,435	1,259	4,301	811	1,154	185	35	29	364	996	35	374	48	5	1,496	249	103			62	.268	.348	.758	766	152.8	.371	117	114
7	Charlie Gehringer C. Gehringer	.404	10,237	2,323	8,860	1,775	2,839	574	146	184	1,427	1,186	50	372	181		4,257	904	141			27	.320	.480	.884	1797	516.6	.405	124	350
8	Buddy Myer B. Myer	.395	6,460	1,492	5,540	963	1,683	286	107	34	690	811	25	362	105		2,285	427	84			12	.304	.412	.808	996	180.5	.377	113	117.9
9	Yank Robinson Y. Robinson	.394	3,096	720	2,469	506	593	111	29	13	343	559	53	51	261		801	153					.240	.324	.718	569	108.3	.363	114	65.6
10	Joe Morgan J. Morgan	.392	11,329	2,649	9,277	1,650	2,517	449	96	268	1,133	1,865	40	1,015	689	162	3,962	813	51	96	76	105	.271	.427	.819	1717	490	.372	135	447.2
11	George Grantham G. Grantham	.387	3,814	899	3,224	580	953	188	58	68	452	468	13	359	96		1,461	314	109				.296	.453	.840	614	129.3	.386	119	101.3
12	Chuck Knoblauch C. Knoblauch	.386	6,449	1,415	5,545	1,025	1,646	293	61	83	549	718	121	625	350	105	2,310	437	13	52	20	101	.297	.417	.803	954	163.5	.361	114	122.4
13	Rod Carew R. Carew	.383	4,948	1,172	4,450	640	1,458	212	52	46	473	399	15	547	172	81	1,912	310	57	27	51	108	.328	.430	.812	723	206.9	.367	131	171.4
14	Miller Huggins M. Huggins	.382	6,800	1,586	5,558	948	1,474	146	50	9	318	1,003	47	556	324		1,747	205	192				.265	.314	.696	873	162.4	.350	111	88.5
15	Tony Lazzeri T. Lazzeri	.380	7,160	1,686	6,177	965	1,808	329	115	173	1,171	847	21	834	148		2,886	617	115			3	.293	.467	.847	1156	253.6	.387	122	211
16	Nap Lajoie N. Lajoie	.379	9,352	2,224	8,554	1,325	2,874	585	132	67	1,370	474	118	296	340		3,924	784	206				.336	.459	.838	1564	532.9	.399	145	486.2
17	Tom Daly T. Daly	.376	4,633	1,092	4,030	747	1,178	202	73	35	604	500	39	378	267		1,631	310	64				.292	.405	.781	784	115.7	.374	113	93
18	Willie Randolph W. Randolph	.373	9,462	2,202	8,018	1,239	2,210	316	65	54	687	1,243	38	675	271	94	2,818	435	99	64	37	219	.276	.351	.724	1181	119.4	.335	110	108.3
19	Billy Goodman B. Goodman	.373	3,049	729	2,675	396	800	142	23	9	233	307	11	126	17	17	1,015	174	49	7	4	41	.299	.379	.752	396	45.1	.348	100	1.3
20	Bobby Grich B. Grich	.373	7,328	1,786	6,124	925	1,632	292	41	204	777	983	78	1,113	83	70	2,618	537	101	42	43	142	.266	.427	.800	1062	250.3	.364	130	245.9
21	Quilvio Veras Q. Veras	.372	3,293	767	2,780	469	750	129	15	32	239	427	38	462	183	83	1,005	176	29	19	4	44	.270	.362	.734	422	5.9	.336	103	11.9
22	Roberto Alomar R. Alomar	.371	10,400	2,379	9,073	1,508	2,724	504	80	210	1,134	1,032	50	1,140	474	114	4,018	794	148	97	62	206	.300	.443	.814	1526	275.7	.359	118	230.8
23	Craig Biggio C. Biggio	.371	9,216	2,058	7,948	1,432	2,262	503	44	228	897	901	232	1,300	328	97	3,537	775	68	67	51	117	.285	.445	.816	1361	224.9	.360	119	221.1
24	Frankie Frisch F. Frisch	.370	8,398	1,928	7,552	1,265	2,380	399	105	82	1,019	634	27	212	315		3,235	586	185				.315	.428	.799	1222	174.5	.369	111	127.4
25	Snuffy Stirnweiss S. Stirnweiss	.368	3,407	815	2,934	495	807	130	57	28	219	428	6	352	105	0	1,135	215	39			52	.275	.387	.755	447	59.5	.360	112	38.9